BrainRegionLAC FD HT MPO

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Median Preoptic Nucleus

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This page covers biological details of component Median Preoptic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Median Preoptic Nucleus (LAC.FD.HT.MPO) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Autonomous Control Area
  • Role: relay
  • Function: generates thirst
  • Notes to function: Drinking decreases noradrenaline release in median preoptic nucleus

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Components

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  • no child items defined

Connectivity

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LAC.FD.HT.MPO.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.MPD Medial Posterior Dorsal Amygdaloid Nucleus inhibitory-gaba Role for serotonin in moral behavior (AMY -> HYP, abstract)
FMM FMM.FT.HC.CA1D Distal CA1 of Hippocampus excitatory-glu Feeling (HC -> HT, abstract)
LAC LAC.FD.HT.PRM Premammillary Nucleus excitatory-glu (unknown reference)
LAC.HL.TGS.PE5 Peritrigeminal Nucleus excitatory-glu (unknown reference)
LPC LPC.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.TH.PT Paratenial Nucleus of Thalamus excitatory-glu (unknown reference)
LAC LAC.FD.HT.AH Anterior Hypothalamic Nucleus excitatory-glu Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> AH, abstract)
LAC.FD.HT.PV Paraventricular Nucleus excitatory-glu Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> PA, abstract)
LAC.FD.HT.SO Supraoptic Nucleus excitatory-glu Intrahypothalamic connections important for neural control of food intake and energy balance (MPOA -> SON, abstract)
LMC LMC.HL.RP.OB Raphe Obscurus Nucleus excitatory-glu (unknown reference)

Thirdparty Circuits

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References

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