BrainRegionLMC HT TG LDT

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Laterodorsal Tegmental Nucleus

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This page covers biological details of component Laterodorsal Tegmental Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Metencephalon -> Pontine Tegmental Nuclei (HT.TG) -> Laterodorsal Tegmental Nucleus (LMC.HT.TG.LDT) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: processor.autonomic
  • Function: Modulating sustained attention or in mediating alerting responses
  • Notes to function: sleep, waking, motor function, learning and reward

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Components

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Component items:

  • Lateral Tegmental Nucleus
  • Dorsal Tegmental Nucleus (LMC.HT.TG.DTG): accurate landmark navigation
    • Dorsal Tegmental Nucleus Pars Dorsalis
    • Dorsal Tegmental Nucleus Pars Ventralis

Connectivity

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LMC.HT.TG.LDT.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu Regulation of the rapid eye movement (REM) sleep by habenular projection (LHbM -> DTG)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach Head Direction Cell Circuit (IPD -> DTN)
FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus excitatory-glu Head Direction Cell Circuit (LMB -> DTN)
LAC LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus excitatory-glu Simplified NREM sleep-promoting pathway (VLPO -> LDTg)
LRC LRC.HL.NPH Prepositus Nucleus excitatory-glu (unknown reference)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach (unknown reference)
FMM FMM.FD.MB.LMB Lateral Mammillary Nucleus modulatory-ach Hippocampal Formation (DTN -> LMam)
LAC LAC.HL.SAL.ISL Inferior Salivatory Nucleus modulatory-ach (unknown reference)
LAC.HL.SAL.SSL Superior Salivatory Nucleus modulatory-ach (unknown reference)
LRC LRC.HL.NPH Prepositus Nucleus modulatory-ach Head Direction Cell Circuit (DTN -> NPRP)
NSA NSA.FD.TH.SG Suprageniculate Nucleus of Thalamus modulatory-ach Head Direction Cell Circuit (DTN -> SUPGEN)

Thirdparty Circuits

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References

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