BrainRegionLMC MM VTA

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Ventral Tegmental Area

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_VTA


This page covers biological details of component Ventral Tegmental Area. Region is part of aHuman target integrated biological model.

  • *Top-down path to region*: Midbrain Mesencephalon -> Ventral Tegmental Area (LMC.MM.VTA) (see Mind Maps)
  • *Type*: nucleus
  • *Brain area*: Lower Brain - Modulatory Contol Area
  • *Role*: relay
  • *Function*: Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues

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Components

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  • Component items*:
  • *Medial Ventral Tegmental Area*
  • *Parabrachial Pigmented Area*
  • *Paranigral Nucleus*
  • *Parafasciculus Retroflexus Area*
  • *Raphe Nucleus Linearis* (*LMC.HP.RP.LI*): Release of 5-HT was only obtained on stimulation of this nucleus
* *Rostral Linear Nucleus*

Connectivity

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LMC.MM.VTA.dot.png

  • Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FT_BNST FAM.FT.BNST || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference) || || FEC || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || Nucleus Accumbens Core || inhibitory-gaba || [Reward circuit of human brain (NACC -> VTA, abstract)] || || LMC || BrainRegionLMC_HP_TG_VTG LMC.HP.TG.VTG || Ventral Tegmental Nucleus || excitatory-glu || (unknown reference) ||

  • Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FT_AM_CEC FAM.FT.AM.CEC || Central Amygdaloid Nucleus, capsular subdivision || modulatory-da || [Reward circuit of human brain (VTA -> AM, abstract)] || || FEC || BrainRegionFEC_FT_ACC_SH FEC.FT.ACC.SH || Nucleus Accumbens Shell || modulatory-da || [Craving (VTA -> NACC, abstract)] || || FMM || BrainRegionFMM_FD_MB_MMB FMM.FD.MB.MMB || Medial Mammillary Nucleus || modulatory-da || [Mammillary bodies: two memory systems in one (VTN -> MMB)] || || || FMM.FT.HC.CA1D || Distal CA1 of Hippocampus || modulatory-da || [Reward circuit of human brain (VTA -> HC, abstract)] || || || FMM.NC.PH.LEC || Lateral Entorhinal Cortex || modulatory-da || [Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)] || || LAC || BrainRegionLAC_FD_HT_PO LAC.FD.HT.PO || Preoptic Nucleus || modulatory-da || [Physiology and pathophysiology of lower urinary tract (VTA -> MPOA)] || || || LAC.FD.HT.PRM || Premammillary Nucleus || modulatory-da || (unknown reference) || || || LAC.FD.HT.PV || Paraventricular Nucleus || modulatory-da || [Physiology and pathophysiology of lower urinary tract (VTA -> PVN)] || || NDM || BrainRegionNDM_NC_AL_DACG NDM.NC.AL.DACG || Dorsal Anterior Cingulate Area || modulatory-da || (unknown reference) || || || NDM.NC.AL.FPC || Lateral Frontopolar Cortex || modulatory-da || [Reward circuit of human brain (VTA -> PFC, abstract)] ||

Thirdparty Circuits

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References

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