BrainRegionNCP NC INS PIC

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Posterior Insular Cortex

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This page covers biological details of component Posterior Insular Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) -> Posterior Insular Cortex (NCP.NC.INS.PIC) (see Mind Maps)
  • Type: cortex
  • Quality: L0
  • Brain area: Neocortical Brain - Conscious Personality Area (NCP)
  • Area circuit: Body Self (BSF)
  • Brodmann ID: 13
  • Role: cortex.sensory.primary
  • Function: Awareness and sensation of pain

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Components

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  • no child items defined

Connectivity

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NCP.NC.INS.PIC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
LPC LPC.HT.PRF.PB Parabrachial Nucleus excitatory-glu Gustatory sensory system of rat and macaque (PB -> Gud, abstract)
NCP NCP.FD.TH.VPI Ventral Posteroinferior Nucleus excitatory-glu Pain matrix (TH.VPI -> INS)
NCP.FD.TH.VPM Ventral Posteromedial Nucleus excitatory-glu Amygdalar disruption of prefrontal cortex (TH -> INS, abstract)
NCP.NC.SPL.SA Somatosensory Association Cortex feedforward-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus excitatory-glu Afferent pain pathways (Insula -> AMY, abstract)
NCP NCP.NC.INS.AIC Anterior Insular Cortex feedforward-glu Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)
NCP.NC.INS.PPC Peripaleocortical Claustral feedforward-glu Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract)

Thirdparty Circuits

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EnP=Endopiriform Nucleus,FAM.FT.EPF
Gud=Insular Cortex,NC.INS
Gug=Insular Cortex,NC.INS
HF=Hippocampal Formation,FMM.FT.HF
IadIap=Insular Cortex,NC.INS
Iav=Insular Cortex,NC.INS
NST=Solitary Nucleus,LPC.HL.SOL
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PiR=Piriform Cortex,NSA.NC.PH.PIR
PrC=Perirhinal Cortex,FMM.NC.PH.PER
VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM

ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
AMY=Amygdala,FAM.FT.AM
BG=Basal Ganglia,FEC.FT.BG
Cerebellum=Cerebellar Complex,LLC.HT.CRC
Insula=Insular Cortex,NC.INS
PAG=Periaqueductal Gray Matter,LMC.MM.PAG
PB=Parabrachial Nucleus,LPC.HT.PRF.PB
PFC=Prefrontal Cortex,NC.AL.PFC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2
SC=Posterior/Dorsal Horn,BMA.SC.PH
Thalamus=Sensory Thalamus,FD.TH.SR

INS=Posterior Insular Cortex,NCP.NC.INS.PIC
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI
TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM


References

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