Difference between revisions of "BrainRegionLAC FD HT VLPO"

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| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || (unknown reference)
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> VLPO, abstract)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Eating and sleeping to survive (DMH -> VLPO)]
 
|-
 
|-
−
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (TMN -> VLPO, abstract)]
+
|  || [[BrainRegionLAC_FD_HT_SCN|LAC.FD.HT.SCN]] || Suprachiasmatic Nucleus || excitatory-glu || (unknown reference)
 +
|-
 +
|  || [[BrainRegionLAC_FD_HT_TBM|LAC.FD.HT.TBM]] || Tuberomammillary Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (TMN -> VLPO)]
 
|-
 
|-
 
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference)
 
|  || [[BrainRegionLAC_FD_HT_VM|LAC.FD.HT.VM]] || Ventromedial Hypothalamic Nucleus || excitatory-glu || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO, abstract)]
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (LC -> VLPO)]
 
|-
 
|-
 
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_NC_PH_PRP|NSA.NC.PH.PRP]] || Prepyriform Cortex || excitatory-glu || (unknown reference)
 
| [[BrainAreaNSA|NSA]] || [[BrainRegionNSA_NC_PH_PRP|NSA.NC.PH.PRP]] || Prepyriform Cortex || excitatory-glu || (unknown reference)
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| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
 
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] || Lateral Habenula Lateral Part || excitatory-glu || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
 
|-
 
|-
−
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
+
|  || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LPO -> LHbM)]
 
|-
 
|-
 
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || excitatory-glu || (unknown reference)
 
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || excitatory-glu || (unknown reference)
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || Laterodorsal Tegmental Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg, abstract)]
+
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_TG_LDT|LMC.HT.TG.LDT]] || Laterodorsal Tegmental Nucleus || excitatory-glu || [http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html Simplified NREM sleep-promoting pathway (VLPO -> LDTg)]
 
|}
 
|}
  
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<img src="http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg" alt="unavailable" style="max-width: 100%;">
 
<img src="http://www.nature.com/neuro/journal/v5/n10/images/nn913-F1.jpg" alt="unavailable" style="max-width: 100%;">
 +
 +
* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference]
 +
 +
<img src="http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg" alt="unavailable" style="max-width: 100%;">
  
 
* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
 
* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
  
 
<img src="http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg" alt="unavailable" style="max-width: 100%;">
 
<img src="http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg" alt="unavailable" style="max-width: 100%;">
 +
 +
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference]
 +
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<img src="http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg" alt="unavailable" style="max-width: 100%;">
  
  
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* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 
* http://www.nature.com/neuro/journal/v5/n10/fig_tab/nn913_F1.html
 +
* http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
 
* http://www.scholarpedia.org/article/Habenula
 
* http://www.scholarpedia.org/article/Habenula
 +
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217

Revision as of 23:10, 4 November 2015

Ventrolateral Preoptic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_VLPO

This page covers biological details of component Ventrolateral Preoptic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Preoptic Nucleus (LAC.FD.HT.PO) -> Ventrolateral Preoptic Nucleus (LAC.FD.HT.VLPO) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Autonomous Control Area
  • Role: processor.autonomic
  • Function: mediates non-REM sleep onset
  • Notes to function: lesions in VLPO result in insomnia

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Components

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  • no child items defined

Connectivity

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LAC.FD.HT.VLPO.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.AM.MEA Medial Anterior Amygdaloid Nucleus excitatory-glu Role for serotonin in moral behavior (AMY -> HYP, abstract)
FAM.FT.SEP.LT Lateral Septal Nucleus inhibitory-gaba Cingulate Gyrus (SEP -> HT, abstract)
FEC FEC.HT.PPN.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba (unknown reference)
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu Eating and sleeping to survive (DMH -> VLPO)
LAC.FD.HT.SCN Suprachiasmatic Nucleus excitatory-glu (unknown reference)
LAC.FD.HT.TBM Tuberomammillary Nucleus excitatory-glu Simplified NREM sleep-promoting pathway (TMN -> VLPO)
LAC.FD.HT.VM Ventromedial Hypothalamic Nucleus excitatory-glu (unknown reference)
LMC LMC.HT.LC Locus Coeruleus modulatory-ne Simplified NREM sleep-promoting pathway (LC -> VLPO)
NSA NSA.NC.PH.PRP Prepyriform Cortex excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FD.LHB.LT Lateral Habenula Lateral Part excitatory-glu Habenula Connections (LPO -> LHb, abstract)
FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LPO -> LHbM)
LAC LAC.FD.HT.SUM Supramammillary Nucleus excitatory-glu (unknown reference)
LMC LMC.HT.TG.LDT Laterodorsal Tegmental Nucleus excitatory-glu Simplified NREM sleep-promoting pathway (VLPO -> LDTg)

Thirdparty Circuits

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References

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