Revision as of 09:28, 31 December 2015

Medial Habenula

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This page covers biological details of component Medial Habenula. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Habenula (FAM.FD.HB) -> Medial Habenula (FAM.FD.MHB) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Affective Motivations Area
Role: processor.affective
Function: Encoding negative feedback, indirect
Notes to function: affects VTA, dorsal raphe but via interpeduncular nucleus

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Components

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FAM.FD.MHB.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.SEP.BAC	Bed Nucleus of Anterior Commissure	excitatory-glu	Connectivity map of the habenula (Septum -> M, abstract)
	FAM.FT.SEP.DBB	Diagonal Band of Broca	inhibitory-gaba	Habenula Connections (DBB -> MHb)
	FAM.FT.SEP.MED	Medial Septal Nucleus	modulatory-ach	Both LHb and MHb control the dopaminergic and serotonergic systems (MS -> MHb)
	FAM.FT.SEP.SF	Septofimbrial Nucleus	inhibitory-gaba	Connectivity map of the habenula (Septum -> M, abstract)
	FAM.FT.SEP.TR	Triangular Septal Nucleus	inhibitory-gaba	Connectivity map of the habenula (Septum -> M, abstract)
FEC	FEC.FT.ACC.SH	Nucleus Accumbens Shell	inhibitory-gaba	Connectivity map of the habenula (NAc -> M, abstract)
LMC	LMC.HT.LC	Locus Coeruleus	modulatory-ne	Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> MHB)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	Connectivity map of the habenula (M -> L, abstract)
FEC	FEC.HT.TG.IPD	Interpeduncular Nucleus	excitatory-glu	Connectivity map of the habenula (M -> IPN)
TEA	TARGET.TEA.ENDOCRINE	Endocrine Glands	endocrine-pineal-gland	Habenula Connections (MHb -> PB)

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 | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> L, abstract)]
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-| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_PPN_IPD|FEC.HT.PPN.IPD]] || Interpeduncular Nucleus || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> IPN)]
+| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_HT_TG_IPD|FEC.HT.TG.IPD]] || Interpeduncular Nucleus || excitatory-glu || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> IPN)]
 |-
 | [[BrainAreaTEA|TEA]] || [[BrainRegionTARGET_TEA_ENDOCRINE|TARGET.TEA.ENDOCRINE]] || Endocrine Glands || endocrine-pineal-gland || [http://www.scholarpedia.org/article/Habenula Habenula Connections (MHb -> PB)]