Revision as of 09:51, 10 September 2015

Ventromedial Hypothalamic Nucleus

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This page covers biological details of component Ventromedial Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Autonomous Control Area
Role: relay
Function: Satiety, control of eating
Notes to function: medial of tuberculum

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Components

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LAC.FD.HT.VM.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FT.AM.MPV	Medial Posterior Ventral Amygdaloid Nucleus	inhibitory-gaba	Role for serotonin in moral behavior (AMY -> HYP, abstract)
FMM	FMM.FT.HF.SUBP	Proximal Subiculum	excitatory-glu	(unknown reference)
LAC	LAC.FD.HT.AH	Anterior Hypothalamic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> VMN)
	LAC.FD.HT.AR	Arcuate Nucleus of Hypothalamus	excitatory-glu	Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH)
	LAC.FD.HT.PRM	Premammillary Nucleus	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FT.BNST	Bed Nucleus of Stria Terminalis	excitatory-glu	(unknown reference)
FEC	FEC.FD.STN.CD	Subthalamic Nucleus Caudal	excitatory-glu	(unknown reference)
	FEC.FT.ACC.SH	Nucleus Accumbens Shell	excitatory-glu	Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract)
LAC	LAC.FD.HT.DM	Dorsomedial Hypothalamic Nucleus	excitatory-glu	Intrahypothalamic connections important for neural control of food intake and energy balance (VMN -> DMN)
	LAC.FD.HT.LTN	Lateral Hypothalamic Nucleus	excitatory-glu	Glucose-sensing neural network (VMH -> LHA)
	LAC.FD.HT.PV	Paraventricular Nucleus	excitatory-glu	Glucose-sensing neural network (VMH -> PVH)
	LAC.FD.HT.VLPO	Ventrolateral Preoptic Nucleus	excitatory-glu	(unknown reference)
LMC	LMC.MM.PAG	Periaqueductal Gray Matter	excitatory-glu	Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)
LPC	LPC.HL.SOL	Solitary Nucleus	excitatory-glu	Bowels control brain: gut hormones and obesity (VMN -> NTS)

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 |-
 |  || [[BrainRegionLAC_FD_HT_LTN|LAC.FD.HT.LTN]] || Lateral Hypothalamic Nucleus || excitatory-glu || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> LHA)]
-|-
-|  || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || excitatory-glu || (unknown reference)
 |-
 |  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || [http://ajpregu.physiology.org/content/302/2/R215 Glucose-sensing neural network (VMH -> PVH)]
+|-
+|  || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || (unknown reference)
 |-
 | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_MM_PAG|LMC.MM.PAG]] || Periaqueductal Gray Matter || excitatory-glu || [http://www.jneurosci.org/content/20/4/1589/F9.expansion Spine induction on short primary dendrites in the ventrolateral VMH (VMH -> PAG)]