BrainRegionFEC FT GPE MED

Globus Pallidus External Medial

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This page covers biological details of component Globus Pallidus External Medial. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus External (FEC.FT.GPE) -> Globus Pallidus External Medial (FEC.FT.GPE.MED) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Forebrain - Execution Control Area (FEC)
• Area circuit: Motor Extensor Loop (FECME)
• Role: basal.ganglia.pallidum
• Function: Extensor loop
• Notes to function:
  • Body extensor movements, trunk and girdles

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FD.STN.MED	Subthalamic Nucleus Medial	excitatory-glu	Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey (STN -> GPe, abstract)
	FEC.FT.CN.HD	Caudate Nucleus Head	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (CN.PU -> GP, abstract)
	FEC.FT.PU.MED	Dorsal Putamen Medial	inhibitory-gaba	Basal Ganglia Activity (PU -> GPo, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.GPI.MED	Globus Pallidus Internal Medial	inhibitory-gaba	(unknown reference)
	FEC.FT.SNR.DL	Substantia Nigra Pars Reticulata Dorsolateral	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)

Thirdparty Circuits

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• Prefrontal Cortex (PFC) in motor behavior - see Reference (CM.PFC-MOTOR)

CN.PU=Striatum,FEC.FT.ST (see Basal Ganglia)
CR=Cerebellar Complex,LLC.HT.CRC
GP=Globus Pallidus,FEC.FT.GP (see Basal Ganglia)
LPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
MC=Motor Cortex,NMA.NC.MC
PMC=Premotor Cortex,NC.PMC
PN=Pontine Nuclear Complex,HT.PN (see Metencephalic Sensory Nuclei)
SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia)
TH=Ventral Thalamus,FD.TH.VTH (see Motor Thalamus)

• Basal Ganglia Activity - see Reference (CM.BASAL-GANGLIA-ACTIVITY)

GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
GPo=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia)
M1=Motor Cortex,NMA.NC.MC
PMC=Premotor Cortex,NC.PMC
PU=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
SMC=Supplementary Motor Cortex,NMA.NC.SMC
SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia)
STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
VLo=Ventral Lateral Nucleus,NMA.FD.TH.VL

References

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• https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988
• http://thebrain.mcgill.ca/flash/a/a_06/a_06_cr/a_06_cr_mou/a_06_cr_mou.html