BrainRegionNMA NC PMC F7

Dorsal Rostral Premotor Cortex

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This page covers biological details of component Dorsal Rostral Premotor Cortex. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) -> Dorsal Premotor Cortex (MCA.NC.DPMC) -> Dorsal Rostral Premotor Cortex (NMA.NC.PMC.F7) (see Mind Maps)
• Type: cortex
• Quality: L0
• Brain area: Neocortical Brain - Motor Aggregation Area (NMA)
• Area circuit: Extensor Motor (XTM)
• Brodmann ID: 06
• Role: cortex.motor.extensor
• Function: Associate arbitrary sensory stimuli with specific eye movements
• Notes to function:
  • 6DR
  • Can evoke eye movements
  • strong afferents from DLPFC
  • convey inputs to caudal concerning motivation, long term plans, memory of past actions
  • integrates sensory and internally driven inputs for planning of goal-directed actions

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
NCP	NCP.NC.SPL.SA	Somatosensory Association Cortex	feedforward-glu	uncertain	3 Visual Cortex Paths (SPL -> dPM, abstract)
NDM	NDM.NC.AL.DACG	Dorsal Anterior Cingulate Area	feedforward-glu	uncertain	(unknown reference)
	NDM.NC.AL.DLPFCR	Rostral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	uncertain	Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
NPE	NPE.NC.IPS.LIP	Lateral Intraparietal Sulcus	feedforward-glu	uncertain	Global visual system (ParietalCortex -> FrontalCortex, abstract)
	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	feedforward-glu	uncertain	(unknown reference)
NSA	NSA.NC.TTG.A1	Primary Auditory Cortex	feedforward-glu	uncertain	Dual Auditory Processing (A1 -> DLPFC, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
NMA	NMA.NC.PMC.F2	Dorsal Caudal Premotor Cortex	feedforward-glu	uncertain	(unknown reference)

Thirdparty Circuits

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• Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

• Cortico-Cortical Connectivity - see Reference (CL.CORTICO-CORTICAL-CONNECTIVITY)

A1=Primary Auditory Cortex,NSA.NC.TTG.A1
AA=Wernicke's area A3,NSA.NC.STG.A3
M1=Motor Cortex,NMA.NC.MC
MA=Premotor Cortex,NC.PMC
PFC=Prefrontal Cortex,NC.AL.PFC
PTHA=Inferior Parietal Lobule,NC.IPL
S1=Primary Somatosensory Cortex,NCP.NC.PG.S1
SA=Somatosensory Association Cortex,NCP.NC.SPL.SA
V1=Primary Visual Cortex,NSA.NC.OCC.V1
VA=Secondary Visual Cortex,NSA.NC.OCC.V2 (see Occipital Lobe)

References

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• http://www.sciencedirect.com/science/article/pii/S0959438808001566
• http://www.sciencedirect.com/science/article/pii/S1053810011000080