BrainCenterNC AL LPFC
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Lateral Prefrontal Cortex
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This page covers biological details of component group Lateral Prefrontal Cortex. Component group is part of aHuman target integrated biological model.
- Top-down path to center: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Lateral Prefrontal Cortex (NC.AL.LPFC) (see Mind Maps)
- Function: High-level Rational Thinking Functions
(generated)
Components
(generated)
Component items:
- Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFC): Temporal Integration and working memory
- Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR): Cognitive control and monitoring to resolve conflict in information processing and competing response plans
- Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL): Cognitive control related to stimulus processing and selection of relevant information for behavior
- Ventrolateral Prefrontal Cortex (NC.AL.VLPFC)
- Inferior Prefrontal Gyrus (NDM.NC.AL.IPG): Processing of syntax in oral and sign languages
- Broca's Area (NPE.NC.PFC.BRA): Speech Engine
- Broca's Area Pars Opercularis (NPE.NC.BRA.PO): Speech Engine
- Broca's Area Pars Triangularis (NPE.NC.BRA.PT): Language production and prefrontal associational integration, propositional language comprehension
Connectivity
(generated)
Internal Regions Connections:
| Source Region | Target Region | Reference |
| Inferior Prefrontal Gyrus (NDM.NC.AL.IPG) | Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL) | Directed Effort Network (fPole -> DLPFC, abstract) |
External Connections:
External Inbound Center Connections:
| Source Center | Reference |
| Thalamus (FD.TH) | Saccadic Vision (Thalamus -> FrontalCortex, abstract) |
| Cerebellar Complex (LLC.HP.CRC) | (unknown reference) |
| Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) | Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract) |
| Insular Cortex (NC.INS) | Directed Effort Network (Insula -> fPole, abstract) |
| Inferior Parietal Lobule (NC.IPL) | Cortico-Cortical Connectivity (PTHA -> PFC, abstract) |
| Occipital Lobe (NC.LOBE.OCC) | Cortico-Cortical Connectivity (VA -> PFC, abstract) |
| Medial Parietal Lobule (NC.MPL) | Prefrontal Cortex (PFC) in emotional behavior (PCA -> LPFC, abstract) |
| Premotor Cortex (NC.PMC) | Cortico-Cortical Connectivity (MA -> PFC, abstract) |
| Superior Temporal Gyrus (NC.STG) | Language-Related Regions (TC -> vIFC) |
| Inferotemporal Area (NSA.NC.IT) | 3 Visual Cortex Paths (IT -> LPC, abstract) |
External Outbound Center Connections:
| Target Center | Reference |
| Basal Ganglia (BGA.FT.BG) | Global visual system (FrontalCortex -> BGA, abstract) |
| Thalamus (FD.TH) | Prefrontal Cortex (PFC) in motor behavior (LPFC -> TH, abstract) |
| Pontine Reticular Formation (HP.RF) | Vocal Control (Broca -> RF, abstract) |
| Anterior Cingulate Area (NC.ACG) | Prefrontal Cortex (PFC) in emotional behavior (LPFC -> ACG, abstract) |
| Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) | (unknown reference) |
| Inferior Parietal Lobule (NC.IPL) | Cortical Auditory System (IFC44 -> IPL40, abstract) |
| Premotor Cortex (NC.PMC) | Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract) |
| Supplementary Motor Cortex (NMA.NC.SMC) | 3 Visual Cortex Paths (LPC -> pre-SMA, abstract) |
