BrainRegionLRC MM PT PON

Pretectal Olivary Nucleus

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This page covers biological details of component Pretectal Olivary Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Reflexes Nuclei of Midbrain Mesencephalon (MM.REF) -> Visual Reflexes Nuclei of Midbrain Mesencephalon (MM.REF.VIS) -> Pretectum (MM.PT) -> Pretectal Olivary Nucleus (LRC.MM.PT.PON) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Motor Reflex Area
• Role: processor.automatic
• Function: Pupillary light reflex and modulating subcortical nuclei involved in circadian rhythms
• Notes to function:
  • Primary visual centre, involved in the pupillary light reflex, receives retinal input

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.FD.RT	Retinal Nucleus	excitatory-glu	Effect of light on pupil diameter (RET -> OPN)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LAC	LAC.MM.EWN	Edinger-Westphal Nucleus	excitatory-glu	Effect of light on pupil diameter (OPN -> EW)
NSA	NSA.FD.LGN	Lateral Geniculate Nucleus	excitatory-glu	(unknown reference)

Thirdparty Circuits

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• Effect of light on pupil diameter - see Reference (CP.PUPIL-REFLEX)

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
EW=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
GC=Ciliary Ganglion,LAC.PN.PSYM.CLG
IML=Ciliospinal Center,LAC.SC.IZ.CSC
LC=Locus Coeruleus,LMC.HT.LC
OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
RET=Retinal Nucleus,LPC.FD.RT
SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

References

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• http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full