BrainRegionLAC MM EWN
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Edinger-Westphal Nucleus
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This page covers biological details of component Edinger-Westphal Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Perhipheral Nuclei of Midbrain Mesencephalon (MM.PER) -> Edinger-Westphal Nucleus (LAC.MM.EWN) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Autonomous Control Area (LAC)
- Area circuit: Vision Autonomic Control (LAV)
- Role: parasympathetic.nucleus
- Function: Change Eye Pupil
- Notes to function:
- Parasympathetic nucleus, parvocellular extention of OCN
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| LRC | LRC.MM.DSCH | Darkschewitsch Nucleus | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (SupraOculomotor -> EWN, abstract) |
| LRC.MM.PT.PON | Pretectal Olivary Nucleus | excitatory-glu | uncertain | Effect of light on pupil diameter (OPN -> EW) | |
| LRC.MM.PT.PR | Principal Pretectal Nucleus | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract) | |
| LRC.MM.PT.SL | Sublentiform Nucleus | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (Pretectum -> EWN, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| LAC | LAC.PN.PSYM.CLG | Ciliary Ganglion | excitatory-glu | uncertain | Autonomic nervous system (EWN -> CLG) |
| LAC.PN.PSYM.EPG | Episcleral Ganglion | excitatory-glu | uncertain | Autonomic nervous system (EWN -> EPG) |
Thirdparty Circuits
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- Autonomic nervous system - see Reference (CM.AUTONOMIC-MUSCLES)
CLG=Ciliary Ganglion,LAC.PN.PSYM.CLG DM=Vagus Nucleus,LAC.HL.VGN EPG=Episcleral Ganglion,LAC.PN.PSYM.EPG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE ISL=Inferior Salivatory Nucleus,LAC.HL.SAL.ISL OTG=Otic Ganglion,LAC.PN.PSYM.OTG SMG=Submandibular Ganglion,LAC.PN.PSYM.SXG SPG=Sphenopalatine Ganglion,LAC.PN.PSYM.SPG SSL=Superior Salivatory Nucleus,LAC.HL.SAL.SSL
- Vision Components - see Reference (CP.VISION-COMPONENTS)
CG=Ciliary Ganglion,LAC.PN.PSYM.CLG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE LGN=Lateral Geniculate Nucleus,NSA.FD.LGN OCN=Oculomotor Nucleus,LPC.MM.OCN RT=Retinal Ganglion,LPC.PN.SG.RT SOA=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon) STN=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR VAC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) VC=Occipital Lobe,NC.LOBE.OCC
- Eye blink reflex and pupillary light reflex - see Reference (CP.SACCADIC-MOTOR-CONTROL)
Abducens=Abducens Nucleus,LPC.HT.ABD Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE Facial=Facial Motor Nucleus,LPC.HT.FCM Oculomotor=Oculomotor Nucleus,LPC.MM.OCN Pretectum=Pretectum,MM.PT (see Reflexes Nuclei of Midbrain Mesencephalon) PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR RF=Pontine Reticular Formation,HT.RF SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon) VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
- Effect of light on pupil diameter - see Reference (CP.PUPIL-REFLEX)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM EW=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE GC=Ciliary Ganglion,LAC.PN.PSYM.CLG IML=Ciliospinal Center,LAC.SC.IZ.CSC LC=Locus Coeruleus,LMC.HT.LC OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON PVN=Paraventricular Nucleus,LAC.FD.HT.PV RET=Retinal Nucleus,LPC.FD.RT SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Sympathetic and parasympathetic eye pathways - see Reference (CP.EYE-SYM-PATHWAYS)
CC=Ciliospinal Center,LAC.SC.IZ.CSC CLG=Ciliary Ganglion,LAC.PN.PSYM.CLG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE PHT=Posterior Hypothalamic Nucleus,LAC.FD.HT.PN SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG
References
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