BrainRegionLPC HT ABD
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Abducens Nucleus
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This page covers biological details of component Abducens Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Hindbrain Metencephalon -> Metencephalic Motor Nuclei (HT.MN) -> Abducens Nucleus (LPC.HT.ABD) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Peripheral Control Area (LPC)
- Area circuit: Vision Motor (AVM)
- Role: flexor.nucleus
- Function: Conjugated movements of both eyes
- Notes to function:
- Motoneurons - to muscle, interneurons - to OCN
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| LPC | LPC.HT.FCM | Facial Motor Nucleus | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (Facial -> Abducens) |
| LPC.HT.MVBN | Medial Vestibular Nucleus | excitatory-glu | uncertain | (unknown reference) | |
| LRC | LRC.HT.PRF.RPO | Oral Pontine Reticular Nucleus | excitatory-glu | uncertain | Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract) |
| LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | uncertain | Retina and superior colliculus targets (SC -> Abducens, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| LPC | LPC.MM.OCN | Oculomotor Nucleus | excitatory-glu | uncertain | Vestibulo-ocular reflex (VOR) (Abducens -> Oculomotor) |
| TSA | TARGET.TSA.EYE | Eye | eye-muscle-rotate-vestibular | (none) | Eye blink reflex and pupillary light reflex (Abducens -> EYE) |
Thirdparty Circuits
(generated)
- Extraocular eye muscles - see Reference (CX.EYE-EXTRAOCULAR-MUSCLES)
ABD=Abducens Nucleus,LPC.HT.ABD EYE=Eye,TARGET.TSA.EYE OCN=Oculomotor Nucleus,LPC.MM.OCN TRC=Trochlear Nucleus,LPC.MM.TRH
- Vestibulo-ocular reflex (VOR) - see Reference (CP.VESTIBULO-OCULAR-REFLEX)
Abducens=Abducens Nucleus,LPC.HT.ABD FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) Oculomotor=Oculomotor Nucleus,LPC.MM.OCN PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN
- Eye blink reflex and pupillary light reflex - see Reference (CP.SACCADIC-MOTOR-CONTROL)
Abducens=Abducens Nucleus,LPC.HT.ABD Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE Facial=Facial Motor Nucleus,LPC.HT.FCM Oculomotor=Oculomotor Nucleus,LPC.MM.OCN Pretectum=Pretectum,MM.PT (see Reflexes Nuclei of Midbrain Mesencephalon) PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR RF=Pontine Reticular Formation,HT.RF SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon) VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
- Retina and superior colliculus targets - see Reference (CP.RETINA-SUPERIOR-COLLICULUS)
Abducens=Abducens Nucleus,LPC.HT.ABD LGB=Lateral Geniculate Nucleus,NSA.FD.LGN OCC=Occipital Lobe,NC.LOBE.OCC Oculomotor=Oculomotor Nucleus,LPC.MM.OCN Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus) Retina=Retinal Nucleus,LPC.FD.RT SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) Trochlear=Trochlear Nucleus,LPC.MM.TRH
References
(generated)
