BrainRegionLLC MM RD MG

Magnocellular Part of Red Nucleus

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This page covers biological details of component Magnocellular Part of Red Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Red Nucleus (LLC.MM.RD) -> Magnocellular Part of Red Nucleus (LLC.MM.RD.MG) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Locomotion Control Area (LLC)
• Area circuit: Spinocerebellar Locomotion (LLS)
• Role: subcortical.motor.flexor
• Function: Automatic limbs control by projection to spinal cord L6 interneurons
• Notes to function:
  • excite flexors, inhibit extensors
  • limb control, primarily upper limbs, but no control of fingers
  • 150–200 giant or large-sized neurons in humans
  • facilitating flexor alpha motor neurons and inhibiting extensor alpha motor neurons

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Role	Reference
FEC	FEC.FT.SNC.LT	Substantia Nigra Pars Compacta Lateral	modulatory-da	uncertain	(unknown reference)
LLC	LLC.HT.CR.EN	Emboliform Nucleus	excitatory-glu	uncertain	Cerebellum functional divisions (IP -> RD, abstract)
	LLC.HT.CR.GN	Globose Nucleus	excitatory-glu	uncertain	Cerebellum functional divisions (IP -> RD, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Role	Reference
LPC	LPC.SC.PH.CL	Clarke Nucleus	excitatory-glu	uncertain	(unknown reference)
	LPC.SC.VH.PL	Posterolateral Nucleus	excitatory-glu	uncertain	Motor neurons control (RD -> FAMN, abstract)

Thirdparty Circuits

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• Motor neurons control - see Reference (CM.CR-MN)

CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN

References

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• http://openagrosrl.com/www/page/292/