BrainCenterMM RF

Mesencephalic Reticular Formation

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This page covers biological details of component group Mesencephalic Reticular Formation. Component group is part of aHuman target integrated biological model.

• Top-down path to center: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) (see Mind Maps)
• Function:
• Notes to function: Saccades, fixation, gaze holding and vergence. Space-time coordinated rapid eye movements

(generated)

Components

(generated)

Component items:

• Mesencephalic Reticular Formation, Medial Column (MM.RF.MED)
  • Cuneiform Nucleus: Passive coping strategy to novel, painful or threatening stimuli
  • Subcuneiform Nucleus: Initiation of gait, feedback control of saccade accuracy
• Mesencephalic Reticular Formation, Midline Column (MM.RF.MID)
  • Superior Central Raphe Nucleus: Block or temporarily suspend mnemonic processes in the hippocampus; Hallucinations
  • Dorsal Raphe Nucleus: Regulation of sleep and mood
  • Raphe Interpositus Nucleus: Premotor network for saccades

Connectivity

(generated)

Internal Regions Connections:

Source Region	Target Region	Reference
Raphe Interpositus Nucleus	Subcuneiform Nucleus	(unknown reference)

External Connections: External Inbound Center Connections:

Source Center ID	Source Center Name	Reference
BMA.SC.PH	Posterior/Dorsal Horn	(unknown reference)
FAM.FD.HB	Habenula	Habenula Connections (LHb -> MR, abstract)
FD.TH	Thalamus	(unknown reference)
HM.RF	Medullary Reticular Formation	(unknown reference)
HMC.MN	Myelencephalic Motor Nuclei	(unknown reference)
MM.REF	Reflexes Nuclei of Midbrain Mesencephalon	Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract)
NMA.NC.SMC	Supplementary Motor Cortex	Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)

External Outbound Center Connections:

Target Center ID	Target Center Name	Reference
BGA.FD.STA	Subthalamus Area	(unknown reference)
FAM.FD.HB	Habenula	(unknown reference)
FAM.FT.EXTAM	Extended Amygdala	(unknown reference)
FD.TH	Thalamus	(unknown reference)
HM.RF	Medullary Reticular Formation	(unknown reference)
HMC.MPS	Myelencephalic Parasympathetic Nuclei	(unknown reference)
HMT.MN	Metencephalic Motor Nuclei	(unknown reference)
HP.RF	Pontine Reticular Formation	(unknown reference)
HTA.FD.HT	Hypothalamus	(unknown reference)