BrainRegionFAM FT SEP MED
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Medial Septal Nucleus
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This page covers biological details of component Medial Septal Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Septal Nuclei (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Medial Septal Group (FAM.FT.SEP.MG) -> Medial Septal Nucleus (FAM.FT.SEP.MED) (see Mind Maps)
- Type: nucleus
- Brain area: Forebrain - Affective Motivations Area
- Role: relay
- Function: affect HC for spatial learning, generation of theta waves
- Notes to function: output nucleus; projections from AM and HC overlap; control theta rythm and exprolatory behavior; from/to MFB to fornix fimbria
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Components
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Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | Attractor Network in Hippocampus (CA1 -> SEP, abstract) |
LAC | LAC.FD.HT.SUM | Supramammillary Nucleus | excitatory-glu | Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
FEC | FEC.FD.TH.PF | Parafascicular Nucleus of Thalamus | modulatory-ach | (unknown reference) |
FMM | FMM.FD.MB.LMB | Lateral Mammillary Nucleus | modulatory-ach | Cingulate Gyrus (SEP -> HT, abstract) |
FMM.FD.MB.MMB | Medial Mammillary Nucleus | inhibitory-gaba | Cingulate Gyrus (SEP -> HT, abstract) | |
NCP | NCP.NC.MPL.RSC | Retrosplenial Cortex | modulatory-ach | Medial mammillary nucleus and theta rhythm (SEP -> RSP, abstract) |
NDM | NDM.FD.TH.MDM | Medial Mediodorsal Nucleus of Thalamus | modulatory-ach | Thalamocortical relationships (s1MD -> MD, abstract) |
Thirdparty Circuits
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References
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