Substantia Nigra Pars Compacta Lateral

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This page covers biological details of component Substantia Nigra Pars Compacta Lateral. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Substantia Nigra (BGA.FT.SN) -> Substantia Nigra Pars Compacta (LMC.FT.SNC) -> Substantia Nigra Pars Compacta Lateral (FEC.FT.SNC.LT) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: relay
Function: executive loop
Notes to function: DP, dorsal circuits

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Components

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Connectivity

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FEC.FT.SNC.LT.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	excitatory-glu	Habenula Connections (LHb -> SNc, abstract)
	FAM.HP.PPN.IPD	Interpeduncular Nucleus	modulatory-ach	(unknown reference)
FEC	FEC.FT.CN.HD	Caudate Nucleus Head	inhibitory-gaba	Saccades and smooth movements (CN -> SN, abstract)
	FEC.FT.GPI.DS	Globus Pallidus Internal Dorsal	inhibitory-gaba	Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)
	FEC.FT.SNR.RM	Substantia Nigra Pars Reticulata Rostromedial	inhibitory-gaba	(unknown reference)
LRC	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Global visual system (SCi -> SNc, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FT.PU.LT	Dorsal Putamen Lateral	modulatory-da	Physiology and pathophysiology of lower urinary tract (SNC -> PU)
	FEC.FT.PU.MED	Dorsal Putamen Medial	modulatory-da	Basal Ganglia Activity (SN -> PU, abstract)
LLC	LLC.HP.CR.CC	Cerebrocerebellum	modulatory-da	Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)
	LLC.MM.RD	Red Nucleus	modulatory-da	(unknown reference)