Diagonal Band of Broca

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This page covers biological details of component Diagonal Band of Broca. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Extended Amygdala (FAM.FT.EXTAM) -> Septal Nuclei (FAM.FT.SEP) -> Dorsal Septal Nucleus (FAM.FT.SEP.DS) -> Medial Septal Group (FAM.FT.SEP.MG) -> Diagonal Band of Broca (FAM.FT.SEP.DBB) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Affective Motivations Area
Role: processor.affective.memory
Function: involved in generation of theta waves in hippocampus
Notes to function: ACh and GABA; ventral group - from stria terminalis to/from MFB

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Components

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Connectivity

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FAM.FT.SEP.DBB.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LAC	LAC.FD.HT.SUM	Supramammillary Nucleus	excitatory-glu	Medial mammillary nucleus and theta rhythm (SupraMM -> SEP, abstract)
LMC	LMC.HT.LC	Locus Coeruleus	modulatory-ne	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	inhibitory-gaba	Both LHb and MHb control the dopaminergic and serotonergic systems (DBB -> LHbM)
	FAM.FD.MHB	Medial Habenula	inhibitory-gaba	Habenula Connections (DBB -> MHb)
FMM	FMM.FD.MB.MMB	Medial Mammillary Nucleus	inhibitory-gaba	Cingulate Gyrus (SEP -> HT, abstract)
	FMM.FT.HC.CA2	Dorsolateral Cornu Ammonis of Hippocampus	inhibitory-gaba	Medial mammillary nucleus and theta rhythm (SEP -> HF, abstract)
NDM	NDM.NC.AL.VMPFC	Ventromedial Prefrontal Cortex	inhibitory-gaba	(unknown reference)