Ventral Pallidum Ventromedial

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This page covers biological details of component Ventral Pallidum Ventromedial. Region is part of aHuman target integrated biological model.

Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Ventral Pallidum (FEC.FT.VP) -> Ventral Pallidum Ventromedial (FEC.FT.VP.VM) (see Mind Maps)
Type: nucleus
Brain area: Forebrain - Execution Control Area
Role: basal.ganglia.pallidum
Function: motivational loop, NAcc-shell
Notes to function: projects to VTA, MD; circuit - VP-VM-medial, VMPFC, NAcc-medial-shell, MD-rostral-medial; circuit - VP-VM-lateral, VINS, NAcc-VL, MD-central

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Components

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Connectivity

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FEC.FT.VP.VM.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FD.STN.DL	Subthalamic Nucleus Dorsolateral	excitatory-glu	Functional subdivisions of the subthalamic nucleus (STN -> VP, abstract)
	FEC.FT.ACC.SH	Nucleus Accumbens Shell	inhibitory-gaba	Craving (NACC -> VPAL, abstract)
	FEC.FT.IPAC.LT	Lateral Interstitial Anterior Commissural Nucleus	inhibitory-gaba	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FAM	FAM.FD.LHB.MED	Lateral Habenula Medial Part	inhibitory-gaba	Both LHb and MHb control the dopaminergic and serotonergic systems (VP -> LHbM, abstract)
	FAM.FD.TH.PT	Paratenial Nucleus of Thalamus	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)
FEC	FEC.HT.TG.PPN	Pedunculopontine Tegmental Nuclei	inhibitory-gaba	Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VPAL -> PPTG, abstract)
	FEC.HT.TG.RMTG	Rostromedial Tegmental Nucleus	inhibitory-gaba	(unknown reference)
LMC	LMC.MM.VTA	Ventral Tegmental Area	inhibitory-gaba	Craving (VPAL -> VTA, abstract)
NCP	NCP.FD.TH.MDC	Central Mediodorsal Nucleus of Thalamus	inhibitory-gaba	Saccadic Vision (BG -> Thalamus, abstract)