BrainRegionLPC SC PH CL

Clarke Nucleus

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This page covers biological details of component Clarke Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Spinal Cord -> Posterior/Dorsal Horn (BMA.SC.PH) -> Lamina V, VI (BMA.SC.PH.L56) -> Clarke Nucleus (LPC.SC.PH.CL) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: processor.automatic
• Function: Unconscious Proprioception
• Notes to function: To CR

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Components

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Component items:

• Clarke's Nucleus of Lumbar Spinal Cord
• Clarke's Nucleus of Thoracic Spinal Cord

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.PN.SG.LDRG	Lower Dorsal Root Ganglion	excitatory-glu	(unknown reference)
	LPC.PN.SG.UDRG	Upper Dorsal Root Ganglion	excitatory-glu	(unknown reference)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LLC	LLC.HL.ARC	Arcuate Nucleus of Medulla	excitatory-glu	(unknown reference)
	LLC.HT.CR.PV	Cerebellar Paravermis	excitatory-glu	Afferent pain pathways (SC -> Cerebellum, abstract)
	LLC.HT.PN.PBB	Pontobulbar Body	excitatory-glu	(unknown reference)
LRC	LRC.MM.CNF	Cuneiform Nucleus	excitatory-glu	(unknown reference)

Thirdparty Circuits

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• Afferent pain pathways - see Reference

• Cerebellum functional divisions - see Reference

References

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• http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
• http://instruct.uwo.ca/anatomy/530/cblm.htm