BrainRegionFEC FT ACC CORE

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Nucleus Accumbens Core

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This page covers biological details of component Nucleus Accumbens Core. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (BGA.FT.BG) -> Striatum (BGA.FT.ST) -> Ventral Striatum (BGA.FT.VST) -> Accumbens Nucleus (FEC.FT.ACC) -> Nucleus Accumbens Core (FEC.FT.ACC.CORE) (see Mind Maps)
  • Type: nucleus
  • Brain area: Forebrain - Execution Control Area
  • Role: relay
  • Function: cognitive processing of motor function related to reward and reinforcement; encodes new motor programs which facilitate acquisition of given reward in future

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Components

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Connectivity

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FEC.FT.ACC.CORE.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.TH.PT Paratenial Nucleus of Thalamus excitatory-glu (unknown reference)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu Amygdala and its network (BLN -> NACC, abstract)
FMM FMM.FD.TH.RH Rhomboidal Nucleus of Thalamus excitatory-glu (unknown reference)
FMM.FT.HF.SUBD Distal Subiculum excitatory-glu Nucleus Accumbens (SUB -> NACC, abstract)
FMM.FT.HF.SUBP Proximal Subiculum excitatory-glu Nucleus Accumbens (SUB -> NACC, abstract)
FMM.NC.PH.LEC Lateral Entorhinal Cortex excitatory-glu Nucleus Accumbens (EC -> NACC, abstract)
FMM.NC.PH.PAS Parasubiculum excitatory-glu Nucleus Accumbens (PAS -> NACC, abstract)
FMM.NC.PH.PER Perirhinal Cortex excitatory-glu Nucleus Accumbens (PRR -> NACC, abstract)
LPC LPC.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu (unknown reference)
NDM NDM.NC.AL.FPC Lateral Frontopolar Cortex excitatory-glu Affective basal ganglia circuit (OMPFC -> NACC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FEC FEC.FT.SNC.MED Substantia Nigra Pars Compacta Medial inhibitory-gaba (unknown reference)
FEC.FT.SNR.MED Substantia Nigra Pars Reticulata Medial inhibitory-gaba Craving (NACC -> SNr, abstract)
FEC.FT.VP.DL Ventral Pallidum Dorsolateral inhibitory-gaba Craving (NACC -> VPAL, abstract)
LMC LMC.MM.VTA Ventral Tegmental Area inhibitory-gaba Reward circuit of human brain (NACC -> VTA, abstract)

Thirdparty Circuits

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References

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