BrainRegionFMM NC PH LEC

Lateral Entorhinal Cortex

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This page covers biological details of component Lateral Entorhinal Cortex. Region is part of aHuman target integrated biological model.

• *Top-down path to region*: Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Lateral Entorhinal Cortex (FMM.NC.PH.LEC) (see Mind Maps)
• *Type*: cortex
• *Brain area*: Forebrain - Memory Management Area
• *Brodmann ID*: 28
• *Role*: processor
• *Function*: Memory consolidation, emotioncal aspects
• *Notes to function*: non-spatial input to HC; process information about individual items and locations based on a local frame of reference, primarily using external sensory input; it provides the hippocampus with information about content of experience

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Components

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Connectivity

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• Inbound Region Connections:*

|| *Source Area* || *Source Region* || *Source Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FD_TH_PT FAM.FD.TH.PT || Paratenial Nucleus of Thalamus || excitatory-glu || [Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)] || || || FAM.FT.AM.BP || Parvicellular Basal Amygdaloid Nucleus || excitatory-glu || [Principal Connections of Hippocampus (AM -> EC, abstract)] || || FMM || BrainRegionFMM_FT_HF_SUBD FMM.FT.HF.SUBD || Distal Subiculum || excitatory-glu || [Attractor Network in Hippocampus (SUB -> EC, abstract)] || || || FMM.NC.PH.PER || Perirhinal Cortex || feedforward-glu || [Visual Path to Hippocampus (PRPH -> ER, abstract)] || || LMC || BrainRegionLMC_MM_VTA LMC.MM.VTA || Ventral Tegmental Area || modulatory-da || [Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)] || || LPC || BrainRegionLPC_FD_TH_PV LPC.FD.TH.PV || Paraventricular Nucleus of Thalamus || excitatory-glu || [Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)] || || NSA || BrainRegionNSA_NC_IT_TE NSA.NC.IT.TE || Inferotemporal Cortex || feedforward-glu || [McNaughton Spatial Processing Network (ITCortex -> EnthCortex, abstract)] || || || NSA.NC.PH.PIR || Piriform Cortex || feedforward-glu || [KIV model of cortico-hippocampal formation with subcortical projections for motor actions (PC -> EC, abstract)] || || || NSA.NC.STG.A3 || Wernicke's area A3 || feedforward-glu || (unknown reference) || || || NSA.NC.STG.A4 || Wernicke's area A4 || feedforward-glu || (unknown reference) ||

• Outbound Region Connections:*

|| *Target Area* || *Target Region* || *Target Name* || *Type* || *Reference* || || FAM || BrainRegionFAM_FT_AM_AB FAM.FT.AM.AB || Accessory Basal Amygdaloid Nucleus || excitatory-glu || [Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)] || || FEC || BrainRegionFEC_FT_ACC_CORE FEC.FT.ACC.CORE || Nucleus Accumbens Core || excitatory-glu || [Nucleus Accumbens (EC -> NACC, abstract)] || || FMM || BrainRegionFMM_FT_HC_CA1D FMM.FT.HC.CA1D || Distal CA1 of Hippocampus || excitatory-glu || [Neuronal projections in the hippocampus (ET -> CA1, abstract)] || || || FMM.FT.HC.CA2 || Dorsolateral Cornu Ammonis of Hippocampus || excitatory-glu || [Amygdala and its network (EC -> HC, abstract)] || || || FMM.FT.HC.DG || Dentate Gyrus || excitatory-glu || [Neuronal projections in the hippocampus (ET -> DG, abstract)] || || || FMM.FT.HF.SUBP || Proximal Subiculum || excitatory-glu || [Visual Path to Hippocampus (ER -> H, abstract)] || || NDM || BrainRegionNDM_FD_TH_MDM NDM.FD.TH.MDM || Medial Mediodorsal Nucleus of Thalamus || excitatory-glu || [Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)] ||

Thirdparty Circuits

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References

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