BrainRegionNSA NC STG A4

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Wernicke's area A4

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This page covers biological details of component Wernicke's area A4. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Superior Temporal Gyrus (NC.STG) -> Wernicke's area A4 (NSA.NC.STG.A4) (see Mind Maps)
  • Type: cortex
  • Quality: L0
  • Brain area: Neocortical Brain - Sensory Aggregation Area (NSA)
  • Area circuit: Neocortical Audition Aggregation (NAA)
  • Brodmann ID: 22
  • Role: cortex.generic
  • Function: Coordinate the activation or deactivation of grammar areas
  • Notes to function:
    • 22b, Grammatical areas, phonemic sequences, word comprehension




  • no child items defined



Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
NSA NSA.NC.OCC.MT Middle Temporal Area feedforward-glu uncertain Category-Selectivity Paradigm (IOG -> STS, abstract)
NSA.NC.TTG.A1 Primary Auditory Cortex feedforward-glu uncertain Vocal Control (A1 -> Wernike)
NSA.NC.TTG.A2 Auditory Association Area feedforward-glu uncertain Cortical Auditory System (Belt42 -> AC22)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
FMM FMM.NC.PH.LEC Lateral Entorhinal Cortex feedforward-glu uncertain (unknown reference)
NMA NMA.NC.PMC.F4 Ventral Caudal Premotor Cortex feedforward-glu uncertain Language-Related Regions (pSTC -> PMC, abstract)
NPE NPE.NC.BRA.PT Broca's Area Pars Triangularis feedforward-glu uncertain Language-Related Regions (pSTC -> BA44, abstract)
NPE.NC.IPL.SMW Supramarginal Wernike Cortex feedforward-glu uncertain Cortical Auditory System (AC22 -> IPL40, abstract)
NSA NSA.NC.STG.A3 Wernicke's area A3 feedforward-glu uncertain Cortical Auditory System (AC22 -> STS22)

Thirdparty Circuits


BA44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
BA45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IFG=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
MTG21=Preoccipital Inferotemporal Area,NSA.NC.IT.TEO
PMC=Premotor Cortex,NC.PMC
STG22a=Wernicke's area A3,NSA.NC.STG.A3
STG22b=Wernicke's area A4,NSA.NC.STG.A4
TC=Temporopolar Cortex,NCP.NC.TPC
pSTC=Wernicke's area A4,NSA.NC.STG.A4
vIFC=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG

AC22=Wernicke's area A4,NSA.NC.STG.A4
ACA=Auditory Association Area,NSA.NC.TTG.A2
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
Insula=Insular Cortex,NC.INS
OPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex)
PPC=Inferior Parietal Lobule,NC.IPL
dACC=Dorsal Anterior Cingulate Area,NDM.NC.AL.DACG
fPole=Inferior Prefrontal Gyrus,NDM.NC.AL.IPG
tPole=Temporopolar Cortex,NCP.NC.TPC
vACC=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG

AC22=Wernicke's area A4,NSA.NC.STG.A4
Belt42=Auditory Association Area,NSA.NC.TTG.A2
Core41=Primary Auditory Cortex,NSA.NC.TTG.A1
IFC44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IFC45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IPL40=Supramarginal Gyrus,NC.IPL.SMG (see Inferior Parietal Lobule)
PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)
PMC8=Anterior Frontal Eye Field,NPE.NC.PMC.AFEF
STS22=Wernicke's area A3,NSA.NC.STG.A3

A1=Primary Auditory Cortex,NSA.NC.TTG.A1
Broca=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
M2=Supplementary Motor Cortex,NMA.NC.SMC
MotorV=Trigeminal Motor Nucleus,LPC.HT.TRM
MotorVII=Facial Motor Nucleus,LPC.HT.FCM
NucleusAmbiguus=Ambiguus Nucleus,LPC.HL.AMB
NucleusXII=Hypoglossal Motor Nucleus,LPC.HL.HYG
Premotor24=Ventral Anterior Cingulate Area,NDM.NC.AL.VACG
RF=Pontine Reticular Formation,HT.RF
Wernike=Wernicke's area A4,NSA.NC.STG.A4