Anterior Frontal Eye Field

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This page covers biological details of component Anterior Frontal Eye Field. Region is part of aHuman target integrated biological model.

Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Premotor Cortex (NC.PMC) -> Frontal Eye Field (NMA.NC.PMC.FEF) -> Anterior Frontal Eye Field (NPE.NC.PMC.AFEF) (see Mind Maps)
Type: cortex
Brain area: Neocortical Brain - Unimodal Execution Area
Brodmann ID: 08
Role: cortex.generic
Function: Head and eye movements toward auditory stimuli
Notes to function: longer saccades, dorsomedial - 8A (8Ac, 8Am), but not 8Ar; 8Ac - saccades

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Components

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Connectivity

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NPE.NC.PMC.AFEF.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NDM	NDM.NC.AL.DLPFCL	Lateral Mid-Dorsolateral Prefrontal Cortex	feedforward-glu	Prefrontal Cortex (PFC) in motor behavior (LPFC -> PMC, abstract)
NMA	NMA.FD.TH.MDL	Lateral Mediodorsal Nucleus of Thalamus	excitatory-glu	Oculomotor decision-making (Thalamus -> FEF, abstract)
NPE	NPE.NC.BRA.PO	Broca's Area Pars Opercularis	feedforward-glu	Cortical Auditory System (IFC44 -> PMC8, abstract)
	NPE.NC.PMC.CFEF	Caudal Frontal Eye Field	feedforward-glu	(unknown reference)
	NPE.NC.SMC.SEF	Supplementary Eye Field	feedforward-glu	Summary of eye movement control (SEF -> FEF, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FD.STN.MED	Subthalamic Nucleus Medial	excitatory-glu	Functional subdivisions of the subthalamic nucleus (FEF -> STN, abstract)
	FEC.FT.CN.BD	Caudate Nucleus Body	excitatory-glu	Global visual system (FrontalCortex -> BGA, abstract)
LRC	LRC.HL.PRF.GCR	Gigantocellular Reticular Nucleus	excitatory-glu	Motor neurons control (CTX -> MRF, abstract)
	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
	LRC.MM.CJ	Cajal Nucleus	excitatory-glu	Summary of eye movement control (FEF -> riMLF, abstract)
	LRC.MM.DSCH	Darkschewitsch Nucleus	excitatory-glu	(unknown reference)
	LRC.MM.SC.INT	Intermediate Superior Colliculus	excitatory-glu	Summary of eye movement control (FEF -> SC, abstract)
NMA	NMA.NC.PMC.F5	Ventral Rostral Premotor Cortex	feedforward-glu	Cortical Auditory System (PMC8 -> PMC6, abstract)
	NMA.NC.PMC.F7	Dorsal Rostral Premotor Cortex	feedforward-glu	(unknown reference)