Revision as of 18:59, 28 November 2018

Abducens Nucleus

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This page covers biological details of component Abducens Nucleus. Region is part of aHuman target integrated biological model.

Top-down path to region: Hindbrain Metencephalon -> Metencephalic Motor Nuclei (HT.MN) -> Abducens Nucleus (LPC.HT.ABD) (see Mind Maps)
Type: nucleus
Brain area: Lower Brain - Peripheral Control Area
Role: flexor.nucleus
Function: Conjugated movements of both eyes
Notes to function: Motoneurons - to muscle, interneurons - to OCN

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Components

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no child items defined

Connectivity

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LPC.HT.ABD.dot.png

Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.HT.FCM	Facial Motor Nucleus	excitatory-glu	Eye blink reflex and pupillary light reflex (Facial -> Abducens)
	LPC.HT.MVBN	Medial Vestibular Nucleus	excitatory-glu	(unknown reference)
LRC	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	excitatory-glu	Vestibulo-ocular reflex (VOR) (PPRF -> Abducens, abstract)
	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Retina and superior colliculus targets (SC -> Abducens, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LPC	LPC.MM.OCN	Oculomotor Nucleus	excitatory-glu	Vestibulo-ocular reflex (VOR) (Abducens -> Oculomotor)
TSA	TARGET.TSA.EYE	Eye	eye-muscle-rotate-vestibular	Eye blink reflex and pupillary light reflex (Abducens -> EYE)

Thirdparty Circuits

(generated)

Extraocular eye muscles - see Reference

map: 
ABD=Abducens Nucleus,LPC.HT.ABD
EYE=Eye,TARGET.TSA.EYE
OCN=Oculomotor Nucleus,LPC.MM.OCN
TRC=Trochlear Nucleus,LPC.MM.TRH

Vestibulo-ocular reflex (VOR) - see Reference

map: 
Abducens=Abducens Nucleus,LPC.HT.ABD
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation)
VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB
VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN

Eye blink reflex and pupillary light reflex - see Reference

map: 
Abducens=Abducens Nucleus,LPC.HT.ABD
Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG
EWN=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
Facial=Facial Motor Nucleus,LPC.HT.FCM
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
Pretectum=Pretectum,MM.PT (see Reflexes Nuclei of Midbrain Mesencephalon)
PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
RF=Pontine Reticular Formation,HT.RF
SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR
SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon)
VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)

Retina and superior colliculus targets - see Reference

map: 
Abducens=Abducens Nucleus,LPC.HT.ABD
LGB=Lateral Geniculate Nucleus,NSA.FD.LGN
OCC=Occipital Lobe,NC.LOBE.OCC
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
Retina=Retinal Nucleus,LPC.FD.RT
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
Trochlear=Trochlear Nucleus,LPC.MM.TRH

References

(generated)

@@ Line 1: / Line 1: @@
 <pre style="color: green">Abducens Nucleus</pre>
 @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLPC]] -> [[BrainRegionLPC_HT_ABD]]
@@ Line 55: / Line 54: @@
 * [http://what-when-how.com/wp-content/uploads/2012/04/tmp15F38_thumb.jpg Extraocular eye muscles] - see [http://what-when-how.com/neuroscience/the-cranial-nerves-organization-of-the-central-nervous-system-part-4 Reference]
-map: ABD=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]], EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]], OCN=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]], TRC=[[BrainRegionLPC_MM_TRH|Trochlear Nucleus,LPC.MM.TRH]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/28b978f291b0306f8db2e1f3c7bfaf69.jpg" alt="unavailable" style="max-width: 100%;" height=400 width=400>
+ ABD=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]]
+ EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]]
+ OCN=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]]
+ TRC=[[BrainRegionLPC_MM_TRH|Trochlear Nucleus,LPC.MM.TRH]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/28b978f291b0306f8db2e1f3c7bfaf69.jpg" alt=alt="unavailable" style="max-width: 100%;" height=400 width=400>
 * [http://www.neuroanatomy.wisc.edu/virtualbrain/Images/13R.jpg Vestibulo-ocular reflex (VOR)] - see [http://www.neuroanatomy.wisc.edu/virtualbrain/BrainStem/13VNAN.html Reference]
-map: Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]], FEF=Frontal Eye Field,NMA.NC.PMC.FEF ([[BrainRegionNPE_NC_PMC_CFEF|Caudal Frontal Eye Field]] (NPE.NC.PMC.CFEF), [[BrainRegionNPE_NC_PMC_AFEF|Anterior Frontal Eye Field]] (NPE.NC.PMC.AFEF)), Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]], PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF ([[BrainRegionLRC_HT_PRF_RPO|Oral Pontine Reticular Nucleus]] (LRC.HT.PRF.RPO), [[BrainRegionLRC_HT_PRF_CRF|Caudal Pontine Reticular Nucleus]] (LRC.HT.PRF.CRF), [[BrainRegionLRC_HT_PRF_PVR|Parvocellular Reticular Nucleus]] (LRC.HT.PRF.PVR)), VestibularGanglion=[[BrainCenter|Vestibular Ganglion,LPC.PN.SG.VB]], VestibularNuclei=[[BrainRegionLPC_HT_IVBN|Inferior Vestibular Nuclei,LPC.HT.IVBN]]
+ map:
-<img src="http://www.neuroanatomy.wisc.edu/virtualbrain/Images/13R.jpg" alt="unavailable" style="max-width: 100%;">
+ Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]]
+ FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see [[BrainCenterNC_PMC|Premotor Cortex]])
+ Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]]
+ PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see [[BrainCenterHT_RF|Pontine Reticular Formation]])
+ VestibularGanglion=[[BrainCenterLPC_PN_SG_VB|Vestibular Ganglion,LPC.PN.SG.VB]]
+ VestibularNuclei=[[BrainRegionLPC_HT_IVBN|Inferior Vestibular Nuclei,LPC.HT.IVBN]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/c6c3159e2ee23b093b79c4f69c99a61a.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/oculomotor.jpg Eye blink reflex and pupillary light reflex] - see [http://neuroscience.uth.tmc.edu/s3/chapter07.html Reference]
-map: Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]], Ciliary=[[BrainRegionLAC_PN_PSYM_CLG|Ciliary Ganglion,LAC.PN.PSYM.CLG]], EWN=[[BrainRegionLAC_MM_EWN|Edinger-Westphal Nucleus,LAC.MM.EWN]], EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]], Facial=[[BrainRegionLPC_HT_FCM|Facial Motor Nucleus,LPC.HT.FCM]], Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]], Pretectum=Pretectum,MM.PT ([[BrainRegionLRC_MM_PT_PTA|Anterior Pretectum Nucleus]] (LRC.MM.PT.PTA), [[BrainRegionLRC_MM_PT_NOT|Nucleus of Optic Tract]] (LRC.MM.PT.NOT), [[BrainRegionLRC_MM_PT_PON|Pretectal Olivary Nucleus]] (LRC.MM.PT.PON), [[BrainRegionLRC_MM_PT_PR|Principal Pretectal Nucleus]] (LRC.MM.PT.PR), [[BrainRegionLRC_MM_PT_SL|Sublentiform Nucleus]] (LRC.MM.PT.SL)), PrincipalTrigeminal=[[BrainRegionLPC_HT_PN_PTR|Principal Trigeminal Nucleus,LPC.HT.PN.PTR]], RF=[[BrainCenter|Pontine Reticular Formation,HT.RF]], SpinalTrigeminal=[[BrainRegionLPC_HL_TGS_STR|Spinal Trigeminal Nucleus,LPC.HL.TGS.STR]], SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA ([[BrainRegionLRC_MM_CJ|Cajal Nucleus]] (LRC.MM.CJ), [[BrainRegionLRC_MM_RIMLF|Rostral Interstitial Nucleus of MLF]] (LRC.MM.RIMLF), [[BrainRegionLRC_MM_DSCH|Darkschewitsch Nucleus]] (LRC.MM.DSCH)), VAC=Associative Visual Cortex,NPE.NC.OCC.V3 ([[BrainRegionNPE_NC_OCC_V3D|Dorsal Associative Visual Cortex]] (NPE.NC.OCC.V3D), [[BrainRegionNPE_NC_OCC_V3V|Ventral Associative Visual Cortex]] (NPE.NC.OCC.V3V))
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/5fa88e17ecb33cc14ac9fd42f88cea9f.jpg" alt="unavailable" style="max-width: 100%;">
+ Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]]
+ Ciliary=[[BrainRegionLAC_PN_PSYM_CLG|Ciliary Ganglion,LAC.PN.PSYM.CLG]]
+ EWN=[[BrainRegionLAC_MM_EWN|Edinger-Westphal Nucleus,LAC.MM.EWN]]
+ EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]]
+ Facial=[[BrainRegionLPC_HT_FCM|Facial Motor Nucleus,LPC.HT.FCM]]
+ Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]]
+ Pretectum=Pretectum,MM.PT (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
+ PrincipalTrigeminal=[[BrainRegionLPC_HT_PN_PTR|Principal Trigeminal Nucleus,LPC.HT.PN.PTR]]
+ RF=[[BrainCenterHT_RF|Pontine Reticular Formation,HT.RF]]
+ SpinalTrigeminal=[[BrainRegionLPC_HL_TGS_STR|Spinal Trigeminal Nucleus,LPC.HL.TGS.STR]]
+ SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
+ VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see [[BrainCenterNC_LOBE_OCC|Occipital Lobe]])
+<img src="http://ahuman.org/svn/ahwiki/images/ext/5fa88e17ecb33cc14ac9fd42f88cea9f.jpg" alt=alt="unavailable" style="max-width: 100%;">
 * [http://2.bp.blogspot.com/-mjoruMnWeaU/TVp_YcF7meI/AAAAAAAAAsQ/8oZIVJrZVnw/s1600/Gray722.png Retina and superior colliculus targets] - see [http://unifiedtao-en.blogspot.ru/2011/03/what-we-see-of-tao.html Reference]
-map: Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]], LGB=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]], OCC=[[BrainCenter|Occipital Lobe,NC.LOBE.OCC]], Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]], Pulvinar=Pulvinar,FD.PV ([[BrainRegionNSA_FD_TH_IPV|Inferior Pulvinar]] (NSA.FD.TH.IPV), [[BrainRegionNSA_FD_TH_LPV|Lateral Pulvinar]] (NSA.FD.TH.LPV), [[BrainRegionNPE_FD_TH_MPV|Medial Pulvinar]] (NPE.FD.TH.MPV), [[BrainRegionNPE_FD_TH_OPV|Oral Pulvinar]] (NPE.FD.TH.OPV)), Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]], SC=Superior Colliculus,MM.SC ([[BrainRegionLRC_MM_SC_SUP|Superficial Superior Colliculus]] (LRC.MM.SC.SUP), [[BrainRegionLRC_MM_SC_INT|Intermediate Superior Colliculus]] (LRC.MM.SC.INT), [[BrainRegionLRC_MM_SC_DEEP|Deep Superior Colliculus]] (LRC.MM.SC.DEEP)), Trochlear=[[BrainRegionLPC_MM_TRH|Trochlear Nucleus,LPC.MM.TRH]]
+ map:
-<img src="http://ahuman.org/svn/ahwiki/images/ext/1e47f3d4848f280932c3d1141f94c3fb.png" alt="unavailable" style="max-width: 100%;">
+ Abducens=[[BrainRegionLPC_HT_ABD|Abducens Nucleus,LPC.HT.ABD]]
+ LGB=[[BrainRegionNSA_FD_LGN|Lateral Geniculate Nucleus,NSA.FD.LGN]]
+ OCC=[[BrainCenterNC_LOBE_OCC|Occipital Lobe,NC.LOBE.OCC]]
+ Oculomotor=[[BrainRegionLPC_MM_OCN|Oculomotor Nucleus,LPC.MM.OCN]]
+ Pulvinar=Pulvinar,FD.PV (see [[BrainCenterFD_TH_SR|Sensory Thalamus]])
+ Retina=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]]
+ SC=Superior Colliculus,MM.SC (see [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]])
+ Trochlear=[[BrainRegionLPC_MM_TRH|Trochlear Nucleus,LPC.MM.TRH]]
+<img src="http://ahuman.org/svn/ahwiki/images/ext/1e47f3d4848f280932c3d1141f94c3fb.png" alt=alt="unavailable" style="max-width: 100%;">

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Revision as of 18:59, 28 November 2018

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Thirdparty Circuits

References

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