BrainRegionLPC MM OCN

Oculomotor Nucleus

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This page covers biological details of component Oculomotor Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Perhipheral Nuclei of Midbrain Mesencephalon (MM.PER) -> Oculomotor Nucleus (LPC.MM.OCN) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Peripheral Control Area
• Role: flexor.nucleus
• Function: Change Eye Direction
• Notes to function: Muscle nucleus

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Components

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Component items:

• Anterior Median Oculomotor Nucleus
• Central Oculomotor Nucleus
• Caudal Central Oculomotor Nucleus
• Dorsal Oculomotor Nucleus
• Intermediate Oculomotor Nucleus
• Medial Oculomotor Nucleus
• Ventral Oculomotor Nucleus

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LPC	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	excitatory-glu	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> Oculomotor)
	LPC.HT.ABD	Abducens Nucleus	excitatory-glu	Vestibulo-ocular reflex (VOR) (Abducens -> Oculomotor)
	LPC.HT.MVBN	Medial Vestibular Nucleus	excitatory-glu	(unknown reference)
	LPC.HT.SVBN	Superior Vestibular Nucleus	excitatory-glu	(unknown reference)
LRC	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	excitatory-glu	Global visual system (RF -> OPN, abstract)
	LRC.MM.CJ	Cajal Nucleus	excitatory-glu	Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract)
	LRC.MM.PT.SL	Sublentiform Nucleus	excitatory-glu	(unknown reference)
	LRC.MM.RIMLF	Rostral Interstitial Nucleus of MLF	excitatory-glu	Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract)
	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Retina and superior colliculus targets (SC -> Oculomotor, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
TSA	TARGET.TSA.EYE	Eye	eye-muscle-rotate-major-inferior-oblique	Eye blink reflex and pupillary light reflex (Oculomotor -> EYE)

Thirdparty Circuits

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• Eye blink reflex and pupillary light reflex - see Reference (CP.SACCADIC-MOTOR-CONTROL)

Abducens=Abducens Nucleus,LPC.HT.ABD
Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG
EWN=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
Facial=Facial Motor Nucleus,LPC.HT.FCM
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
Pretectum=Pretectum,MM.PT (see Reflexes Nuclei of Midbrain Mesencephalon)
PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
RF=Pontine Reticular Formation,HT.RF
SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR
SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon)
VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)

• Extraocular eye muscles - see Reference (CX.EYE-EXTRAOCULAR-MUSCLES)

ABD=Abducens Nucleus,LPC.HT.ABD
EYE=Eye,TARGET.TSA.EYE
OCN=Oculomotor Nucleus,LPC.MM.OCN
TRC=Trochlear Nucleus,LPC.MM.TRH

• Vision Components - see Reference (CP.VISION-COMPONENTS)

CG=Ciliary Ganglion,LAC.PN.PSYM.CLG
EWN=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OCN=Oculomotor Nucleus,LPC.MM.OCN
RT=Retinal Ganglion,LPC.PN.SG.RT
SOA=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon)
STN=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR
VAC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus)
VC=Occipital Lobe,NC.LOBE.OCC

• Vestibulo-ocular reflex (VOR) - see Reference (CP.VESTIBULO-OCULAR-REFLEX)

Abducens=Abducens Nucleus,LPC.HT.ABD
FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex)
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation)
VestibularGanglion=Vestibular Ganglion,LPC.PN.SG.VB
VestibularNuclei=Inferior Vestibular Nuclei,LPC.HT.IVBN

• Retina and superior colliculus targets - see Reference (CP.RETINA-SUPERIOR-COLLICULUS)

Abducens=Abducens Nucleus,LPC.HT.ABD
LGB=Lateral Geniculate Nucleus,NSA.FD.LGN
OCC=Occipital Lobe,NC.LOBE.OCC
Oculomotor=Oculomotor Nucleus,LPC.MM.OCN
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
Retina=Retinal Nucleus,LPC.FD.RT
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
Trochlear=Trochlear Nucleus,LPC.MM.TRH

• Global visual system - see Reference (CP.GLOBAL-VISUAL-SYSTEM)

ATH=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
BGA=Basal Ganglia,FEC.FT.BG
FrontalCortex=Anterior Lobe,NC.LOBE.ANT
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
OPN=Oculomotor Nucleus,LPC.MM.OCN
ParietalCortex=Parietal Lobe,NC.LOBE.PAR
Pulvinar=Pulvinar,FD.PV (see Sensory Thalamus)
RF=Pontine Reticular Formation,HT.RF
Retina=Retinal Nucleus,LPC.FD.RT
SCi=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SCs=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
SNc=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT
SNr=Substantia Nigra Pars Reticulata Dorsolateral,FEC.FT.SNR.DL
SpinalCord=Lamina IX,SC.VH.L9 (see Anterior/Ventral Horn)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
VisualCortex=Occipital Lobe,NC.LOBE.OCC

References

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• http://neuroscience.uth.tmc.edu/s3/chapter07.html
• http://what-when-how.com/neuroscience/the-cranial-nerves-organization-of-the-central-nervous-system-part-4
• http://www.neuroanatomy.wisc.edu/virtualbrain/BrainStem/13VNAN.html
• http://unifiedtao-en.blogspot.ru/2011/03/what-we-see-of-tao.html
• http://www.sciencedirect.com/science/article/pii/S0959438808001566