BrainRegionLMC MM RP DRN
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Dorsal Raphe Nucleus
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This page covers biological details of component Dorsal Raphe Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> Dorsal Raphe Nucleus (LMC.MM.RP.DRN) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Modulatory Contol Area
- Role: processor.autonomic
- Function: Regulation of sleep and mood
- Notes to function: Major source of 5HT; inhibitory nucleus
(generated)
Components
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Component items:
- Serotonergic cell group B7
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FD.LHB.MED | Lateral Habenula Medial Part | excitatory-glu | Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN) |
| FEC | FEC.HT.TG.IPD | Interpeduncular Nucleus | modulatory-ach | Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> DRN) |
| FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> DRN) | |
| LLC | LLC.FD.TH.SF | Subfascicular Nucleus of Thalamus | inhibitory-gaba | (unknown reference) |
| LMC | LMC.HP.RP.LI | Raphe Nucleus Linearis | modulatory-5ht | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| LPC | LPC.FD.TH.PV | Paraventricular Nucleus of Thalamus | modulatory-5ht | (unknown reference) |
Thirdparty Circuits
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References
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