BrainRegionLRC MM RP RIP

Raphe Interpositus Nucleus

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This page covers biological details of component Raphe Interpositus Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Midbrain Mesencephalon -> Mesencephalic Reticular Formation (MM.RF) -> Mesencephalic Reticular Formation, Midline Column (MM.RF.MID) -> Raphe Interpositus Nucleus (LRC.MM.RP.RIP) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Motor Reflex Area
• Role: processor.automatic
• Function: Premotor network for saccades
• Notes to function: Gate activity of burst neurons for vertical and horizontal saccades; omnipause neurons, part of PPRF

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LRC	LRC.MM.SC.SUP	Superficial Superior Colliculus	excitatory-glu	Horizontal saccades and smooth pursuit movements (SC -> RIP, abstract)
NPE	NPE.NC.SMC.SEF	Supplementary Eye Field	excitatory-glu	Horizontal saccades and smooth pursuit movements (FEFSEF -> RIP, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LRC	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	excitatory-glu	Horizontal saccades and smooth pursuit movements (RIP -> PPRF, abstract)
	LRC.MM.SCNF	Subcuneiform Nucleus	excitatory-glu	(unknown reference)

Thirdparty Circuits

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• Horizontal saccades and smooth pursuit movements - see Reference (CP.VISION-SACCADES)

Bechterew=Pontine Reticulotegmental Nucleus,LLC.HT.PRF.RTMG
CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
FEFSEF=Anterior Lobe,NC.LOBE.ANT
LGB=Lateral Geniculate Nucleus,NSA.FD.LGN
PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation)
PrimaryVisual=Primary Visual Cortex,NSA.NC.OCC.V1
RIP=Raphe Interpositus Nucleus,LRC.MM.RP.RIP
SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
Striatum=Striatum,FEC.FT.ST (see Basal Ganglia)
Vestibular=Superior Vestibular Nucleus,LPC.HT.SVBN
VisualAssociation=Caudal Precuneus,NPE.NC.SPL.PG

References

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• http://www.sciencedirect.com/science/article/pii/S0006899301025987