BrainRegionLRC HL NPH

Prepositus Nucleus

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This page covers biological details of component Prepositus Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Hindbrain Myelencephalon -> Myelencephalic Motor Nuclei (HL.MN) -> Prepositus Nucleus (LRC.HL.NPH) (see Mind Maps)
• Type: nucleus
• Quality: L0
• Brain area: Lower Brain - Motor Reflex Area
• Role: processor.automatic
• Function: Integrate PPRF phasic signal to provide tonic signal of abducens
• Notes to function:
  • Part of horizontal gaze holding system

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
LMC	LMC.HT.TG.LDT	Laterodorsal Tegmental Nucleus	modulatory-ach	Head Direction Cell Circuit (DTN -> NPRP)
LPC	LPC.HT.MVBN	Medial Vestibular Nucleus	excitatory-glu	Head Direction Cell Circuit (MVSN -> NPRP)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LMC	LMC.HT.TG.LDT	Laterodorsal Tegmental Nucleus	excitatory-glu	(unknown reference)
LRC	LRC.HL.INM	Intercalated Nucleus of Medulla	excitatory-glu	(unknown reference)
	LRC.MM.PT.NOT	Nucleus of Optic Tract	excitatory-glu	(unknown reference)
	LRC.MM.SCNF	Subcuneiform Nucleus	excitatory-glu	(unknown reference)
NSA	NSA.FD.TH.SG	Suprageniculate Nucleus of Thalamus	excitatory-glu	Head Direction Cell Circuit (NPRP -> SUPGEN)

Thirdparty Circuits

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• Head Direction Cell Circuit - see Reference (CT.HEAD-DIRECTION)

AD=Anterodorsal Nucleus,FMM.FD.TH.AD
DTN=Laterodorsal Tegmental Nucleus,LMC.HT.TG.DTG
EC=Entorhinal Cortex,FMM.NC.PH.ET (see Rhinal Cortex)
HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation)
IPD=Interpeduncular Nucleus,FEC.HT.TG.IPD
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LHAB=Habenula,FAM.FD.HB
LMB=Lateral Mammillary Nucleus,FMM.FD.MB.LMB
MVSN=Medial Vestibular Nucleus,LPC.HT.MVBN
NPRP=Prepositus Nucleus,LRC.HL.NPH
PC=Parietal Lobe,NC.LOBE.PAR
PRHC=Postrhinal Cortex,FMM.NC.PH.POR
PSUB=Postsubiculum,FMM.NC.PH.POS
RSP=Retrosplenial Cortex,NCP.NC.MPL.RSC
SUPGEN=Suprageniculate Nucleus of Thalamus,NSA.FD.TH.SG
VC=Occipital Lobe,NC.LOBE.OCC

References

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• http://www.scholarpedia.org/article/Head_direction_cells