Revision as of 10:06, 10 July 2016

Cerebellar Complex

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This page covers biological details of component group Cerebellar Complex. Component group is part of aHuman target integrated biological model.

Top-down path to center: Hindbrain Metencephalon -> Cerebellar Complex (LLC.HT.CRC) (see Mind Maps)
Function:

(generated)

Components

(generated)

Component items:

Cerebellum (LLC.HT.CR): Motor coordination
- Cerebellar Flocconodular Lobe (LRC.HT.CR.FN): regulates balance
- Cerebellar Lateral Lobe (LLC.HT.CR.CC): planning movement that is about to occur, evaluating sensory information for action, handles intentions
- Spinocerebellum (LLC.HT.CR.SC)
  - Cerebellar Paravermis (LLC.HT.CR.PV): fine-tune body and limb movements
  - Cerebellar Vermis (LRC.HT.CR.VM): balance and spatial orientation, gait
Deep Cerebellar Nuclei (LLC.HT.CR.DCN)
- Dentate Nucleus (LLC.HT.CR.DN): planning, initiation and control of voluntary movements
- Interposed Nucleus (LLC.HT.CR.IP): coordinating agonist/antagonist muscle pairs
  - Emboliform Nucleus (LLC.HT.CR.EN): Modulate motor functions of Red Nucleus
  - Globose Nucleus (LLC.HT.CR.GN): Modulate motor functions of Red Nucleus
- Fastigual Nucleus (LRC.HT.CR.FG): rostral - interprets body motion and places it on spatial planes to estimate movement of body through space; caudal - saccadic eye movements
Basilar Pontine Nuclei (LLC.HT.BPN): convey information from motor cortex to cerebellum regarding intended movements of contralateral arm and leg

Connectivity

(generated)

Internal Regions Connections:

unavailable

Source Region	Target Region	Reference
Basilar Pontine Nuclei (LLC.HT.BPN)	Cerebellar Lateral Lobe (LLC.HT.CR.CC)	Cerebellum functional divisions (PNN -> CRP)
Cerebellar Lateral Lobe (LLC.HT.CR.CC)	Dentate Nucleus (LLC.HT.CR.DN)	Cerebellum functional divisions (CRP -> DN)
Dentate Nucleus (LLC.HT.CR.DN)	Globose Nucleus (LLC.HT.CR.GN)	(unknown reference)
Emboliform Nucleus (LLC.HT.CR.EN)	Globose Nucleus (LLC.HT.CR.GN)	(unknown reference)
Cerebellar Paravermis (LLC.HT.CR.PV)	Emboliform Nucleus (LLC.HT.CR.EN)	Cerebellum functional divisions (CRS -> IP, abstract)
	Globose Nucleus (LLC.HT.CR.GN)	Cerebellum functional divisions (CRS -> IP, abstract)
	Fastigual Nucleus (LRC.HT.CR.FG)	Cerebellum functional divisions (CRS -> FG)
Cerebellar Vermis (LRC.HT.CR.VM)	Fastigual Nucleus (LRC.HT.CR.FG)	Cerebellum functional divisions (CRV -> FG)

External Connections:

unavailable

External Inbound Center Connections:

Source Center	Sample Link	Reference
Posterior/Dorsal Horn (BMA.SC.PH)	LPC.SC.PH.CL -> LLC.HT.CR.PV	Afferent pain pathways (SC -> Cerebellum, abstract)
Basal Ganglia (FEC.FT.BG)	FEC.FT.SNC.LT -> LLC.HT.CR.CC	Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)
Medullary Reticular Formation (HL.RF)	LLC.HL.RF.MLRN -> LLC.HT.CR.PV	(unknown reference)
Myelencephalic Sensory Nuclei (HL.SN)	LLC.HL.IO -> LLC.HT.CR.CC	Cerebellum functional divisions (IO -> CRP)
Pontine Reticular Formation (HT.RF)	LRC.HT.PRF.RPO -> LLC.HT.CR.CC	Saccades and smooth movements (DLPN -> CR, abstract)
Metencephalic Sensory Nuclei (HT.SN)	LLC.HT.PN.RSP -> LLC.HT.CR.DN	Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)
Vestibular Nuclei (LPC.HT.VBN)	LPC.HT.IVBN -> LRC.HT.CR.FN	(unknown reference)
Vestibular Ganglion (LPC.PN.SG.VB)	LPC.PN.SG.SVB -> LRC.HT.CR.FN	(unknown reference)
Motor Cortex (NMA.NC.MC)	NMA.NC.MC -> LLC.HT.BPN	Cerebellum functional divisions (CTX -> PNN, abstract)
Intermediate Zone (SC.IZ)	LPC.SC.IZ.CCV -> LLC.HT.CR.PV	Cerebellum functional divisions (CCV -> CRS)

External Outbound Center Connections:

Target Center	Sample Link	Reference
Cognitive Thalamus (FD.TH.CR)	LLC.HT.CR.DN -> NCP.FD.TH.RIL	(unknown reference)
Motor Thalamus (FD.TH.MR)	LLC.HT.CR.DN -> NMA.FD.TH.VL	Thalamocortical relationships (s1VL -> VL)
Pontine Reticular Formation (HT.RF)	LRC.HT.CR.FG -> LRC.HT.PRF.CRF	Cerebellum functional divisions (FG -> RF, abstract)
Red Nucleus (LLC.MM.RD)	LLC.HT.CR.DN -> LLC.MM.RD	Motor neurons control (LT -> RD)
Vestibular Nuclei (LPC.HT.VBN)	LRC.HT.CR.FG -> LPC.HT.LVBN	Cerebellum functional divisions (FG -> VB, abstract)
Reflexes Nuclei of Midbrain Mesencephalon (MM.REF)	LLC.HT.BPN -> LRC.MM.SC.INT	(unknown reference)
Lateral Prefrontal Cortex (NC.AL.LPFC)	LLC.HT.CR.DN -> NDM.NC.AL.DLPFCL	(unknown reference)

@@ Line 16: / Line 16: @@
 '''Component items''':
 * '''Cerebellum''' (LLC.HT.CR): Motor coordination
-** [[BrainRegionLLC_HT_CR_CC|Cerebrocerebellum]] (LLC.HT.CR.CC): planning movement that is about to occur, evaluating sensory information for action, handles intentions
+** [[BrainRegionLRC_HT_CR_FN|Cerebellar Flocconodular Lobe]] (LRC.HT.CR.FN): regulates balance
-** [[BrainRegionLLC_HT_CR_SC|Spinocerebellum]] (LLC.HT.CR.SC): fine-tune body and limb movements
+** [[BrainRegionLLC_HT_CR_CC|Cerebellar Lateral Lobe]] (LLC.HT.CR.CC): planning movement that is about to occur, evaluating sensory information for action, handles intentions
-** [[BrainRegionLLC_HT_CR_VC|Vestibulocerebellum]] (LLC.HT.CR.VC): balance and spatial orientation, gait
+** '''Spinocerebellum''' (LLC.HT.CR.SC)
+*** [[BrainRegionLLC_HT_CR_PV|Cerebellar Paravermis]] (LLC.HT.CR.PV): fine-tune body and limb movements
+*** [[BrainRegionLRC_HT_CR_VM|Cerebellar Vermis]] (LRC.HT.CR.VM): balance and spatial orientation, gait
 * '''Deep Cerebellar Nuclei''' (LLC.HT.CR.DCN)
 ** [[BrainRegionLLC_HT_CR_DN|Dentate Nucleus]] (LLC.HT.CR.DN): planning, initiation and control of voluntary movements
@@ Line 24: / Line 26: @@
 *** [[BrainRegionLLC_HT_CR_EN|Emboliform Nucleus]] (LLC.HT.CR.EN): Modulate motor functions of Red Nucleus
 *** [[BrainRegionLLC_HT_CR_GN|Globose Nucleus]] (LLC.HT.CR.GN): Modulate motor functions of Red Nucleus
-** [[BrainRegionLLC_HT_CR_FN|Fastigual Nucleus]] (LLC.HT.CR.FN): rostral - interprets body motion and places it on spatial planes to estimate movement of body through space; caudal - saccadic eye movements
+** [[BrainRegionLRC_HT_CR_FG|Fastigual Nucleus]] (LRC.HT.CR.FG): rostral - interprets body motion and places it on spatial planes to estimate movement of body through space; caudal - saccadic eye movements
+* [[BrainRegionLLC_HT_BPN|Basilar Pontine Nuclei]] (LLC.HT.BPN): convey information from motor cortex to cerebellum regarding intended movements of contralateral arm and leg
 = Connectivity =
@@ Line 38: / Line 41: @@
 | '''Source Region''' || '''Target Region''' || '''Reference'''
 |-
-| [[BrainRegionLLC_HT_CR_CC|Cerebrocerebellum]] (LLC.HT.CR.CC) || [[BrainRegionLLC_HT_CR_DN|Dentate Nucleus]] (LLC.HT.CR.DN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRP -> DN)]
+| [[BrainRegionLLC_HT_BPN|Basilar Pontine Nuclei]] (LLC.HT.BPN) || [[BrainRegionLLC_HT_CR_CC|Cerebellar Lateral Lobe]] (LLC.HT.CR.CC) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (PNN -> CRP)]
+|-
+| [[BrainRegionLLC_HT_CR_CC|Cerebellar Lateral Lobe]] (LLC.HT.CR.CC) || [[BrainRegionLLC_HT_CR_DN|Dentate Nucleus]] (LLC.HT.CR.DN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRP -> DN)]
 |-
 | [[BrainRegionLLC_HT_CR_DN|Dentate Nucleus]] (LLC.HT.CR.DN) || [[BrainRegionLLC_HT_CR_GN|Globose Nucleus]] (LLC.HT.CR.GN) || (unknown reference)
@@ Line 44: / Line 49: @@
 | [[BrainRegionLLC_HT_CR_EN|Emboliform Nucleus]] (LLC.HT.CR.EN) || [[BrainRegionLLC_HT_CR_GN|Globose Nucleus]] (LLC.HT.CR.GN) || (unknown reference)
 |-
-| [[BrainRegionLLC_HT_CR_SC|Spinocerebellum]] (LLC.HT.CR.SC) || [[BrainRegionLLC_HT_CR_EN|Emboliform Nucleus]] (LLC.HT.CR.EN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRS -> IP, abstract)]
+| [[BrainRegionLLC_HT_CR_PV|Cerebellar Paravermis]] (LLC.HT.CR.PV) || [[BrainRegionLLC_HT_CR_EN|Emboliform Nucleus]] (LLC.HT.CR.EN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRS -> IP, abstract)]
 |-
 |  || [[BrainRegionLLC_HT_CR_GN|Globose Nucleus]] (LLC.HT.CR.GN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRS -> IP, abstract)]
 |-
-| [[BrainRegionLLC_HT_CR_VC|Vestibulocerebellum]] (LLC.HT.CR.VC) || [[BrainRegionLLC_HT_CR_FN|Fastigual Nucleus]] (LLC.HT.CR.FN) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRV -> FG)]
+|  || [[BrainRegionLRC_HT_CR_FG|Fastigual Nucleus]] (LRC.HT.CR.FG) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRS -> FG)]
+|-
+| [[BrainRegionLRC_HT_CR_VM|Cerebellar Vermis]] (LRC.HT.CR.VM) || [[BrainRegionLRC_HT_CR_FG|Fastigual Nucleus]] (LRC.HT.CR.FG) || [http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CRV -> FG)]
 |}
@@ Line 60: / Line 67: @@
 | '''Source Center''' || '''Sample Link''' || '''Reference'''
 |-
-| [[BrainCenterBMA_SC_PH|Posterior/Dorsal Horn]] (BMA.SC.PH) || [[BrainRegionLPC_SC_PH_CL|LPC.SC.PH.CL]] -> [[BrainRegionLLC_HT_CR_SC|LLC.HT.CR.SC]]||[http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Cerebellum, abstract)]
+| [[BrainCenterBMA_SC_PH|Posterior/Dorsal Horn]] (BMA.SC.PH) || [[BrainRegionLPC_SC_PH_CL|LPC.SC.PH.CL]] -> [[BrainRegionLLC_HT_CR_PV|LLC.HT.CR.PV]]||[http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html Afferent pain pathways (SC -> Cerebellum, abstract)]
 |-
 | [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) || [[BrainRegionFEC_FT_SNC_LT|FEC.FT.SNC.LT]] -> [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (SN -> CR, abstract)]
 |-
-| [[BrainCenterHL_RF|Medullary Reticular Formation]] (HL.RF) || [[BrainRegionLLC_HL_RF_MLRN|LLC.HL.RF.MLRN]] -> [[BrainRegionLLC_HT_CR_SC|LLC.HT.CR.SC]]||(unknown reference)
+| [[BrainCenterHL_RF|Medullary Reticular Formation]] (HL.RF) || [[BrainRegionLLC_HL_RF_MLRN|LLC.HL.RF.MLRN]] -> [[BrainRegionLLC_HT_CR_PV|LLC.HT.CR.PV]]||(unknown reference)
 |-
-| [[BrainCenterHL_SN|Myelencephalic Sensory Nuclei]] (HL.SN) || [[BrainRegionLLC_HL_IO|LLC.HL.IO]] -> [[BrainRegionLLC_HT_CR_GN|LLC.HT.CR.GN]]||(unknown reference)
+| [[BrainCenterHL_SN|Myelencephalic Sensory Nuclei]] (HL.SN) || [[BrainRegionLLC_HL_IO|LLC.HL.IO]] -> [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (IO -> CRP)]
 |-
 | [[BrainCenterHT_RF|Pontine Reticular Formation]] (HT.RF) || [[BrainRegionLRC_HT_PRF_RPO|LRC.HT.PRF.RPO]] -> [[BrainRegionLLC_HT_CR_CC|LLC.HT.CR.CC]]||[http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/saccades.jpg Saccades and smooth movements (DLPN -> CR, abstract)]
@@ Line 72: / Line 79: @@
 | [[BrainCenterHT_SN|Metencephalic Sensory Nuclei]] (HT.SN) || [[BrainRegionLLC_HT_PN_RSP|LLC.HT.PN.RSP]] -> [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]]||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (PN -> CR, abstract)]
 |-
-| [[BrainCenterLPC_HT_VBN|Vestibular Nuclei]] (LPC.HT.VBN) || [[BrainRegionLPC_HT_IVBN|LPC.HT.IVBN]] -> [[BrainRegionLLC_HT_CR_VC|LLC.HT.CR.VC]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (VB -> CRV, abstract)]
+| [[BrainCenterLPC_HT_VBN|Vestibular Nuclei]] (LPC.HT.VBN) || [[BrainRegionLPC_HT_IVBN|LPC.HT.IVBN]] -> [[BrainRegionLRC_HT_CR_FN|LRC.HT.CR.FN]]||(unknown reference)
+|-
+| [[BrainCenterLPC_PN_SG_VB|Vestibular Ganglion]] (LPC.PN.SG.VB) || [[BrainRegionLPC_PN_SG_SVB|LPC.PN.SG.SVB]] -> [[BrainRegionLRC_HT_CR_FN|LRC.HT.CR.FN]]||(unknown reference)
+|-
+| [[BrainRegionNMA_NC_MC|Motor Cortex]] (NMA.NC.MC) || [[BrainRegionNMA_NC_MC|NMA.NC.MC]] -> [[BrainRegionLLC_HT_BPN|LLC.HT.BPN]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CTX -> PNN, abstract)]
 |-
-| [[BrainCenterSC_IZ|Intermediate Zone]] (SC.IZ) || [[BrainRegionLPC_SC_IZ_CBS|LPC.SC.IZ.CBS]] -> [[BrainRegionLLC_HT_CR_SC|LLC.HT.CR.SC]]||(unknown reference)
+| [[BrainCenterSC_IZ|Intermediate Zone]] (SC.IZ) || [[BrainRegionLPC_SC_IZ_CCV|LPC.SC.IZ.CCV]] -> [[BrainRegionLLC_HT_CR_PV|LLC.HT.CR.PV]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (CCV -> CRS)]
 |}
@@ Line 82: / Line 93: @@
 | '''Target Center''' || '''Sample Link''' || '''Reference'''
 |-
-| [[BrainCenterFD_TH_CR|Cognitive Thalamus]] (FD.TH.CR) || [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]] -> [[BrainRegionFEC_FD_TH_RIL|FEC.FD.TH.RIL]]||(unknown reference)
+| [[BrainCenterFD_TH_CR|Cognitive Thalamus]] (FD.TH.CR) || [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]] -> [[BrainRegionNCP_FD_TH_RIL|NCP.FD.TH.RIL]]||(unknown reference)
 |-
 | [[BrainCenterFD_TH_MR|Motor Thalamus]] (FD.TH.MR) || [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]] -> [[BrainRegionNMA_FD_TH_VL|NMA.FD.TH.VL]]||[http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/ Thalamocortical relationships (s1VL -> VL)]
 |-
-| [[BrainCenterHT_RF|Pontine Reticular Formation]] (HT.RF) || [[BrainRegionLLC_HT_CR_FN|LLC.HT.CR.FN]] -> [[BrainRegionLRC_HT_PRF_CRF|LRC.HT.PRF.CRF]]||(unknown reference)
+| [[BrainCenterHT_RF|Pontine Reticular Formation]] (HT.RF) || [[BrainRegionLRC_HT_CR_FG|LRC.HT.CR.FG]] -> [[BrainRegionLRC_HT_PRF_CRF|LRC.HT.PRF.CRF]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (FG -> RF, abstract)]
 |-
-| [[BrainRegionLLC_MM_RD|Red Nucleus]] (LLC.MM.RD) || [[BrainRegionLLC_HT_CR_EN|LLC.HT.CR.EN]] -> [[BrainRegionLLC_MM_RD|LLC.MM.RD]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (IP -> RD, abstract)]
+| [[BrainRegionLLC_MM_RD|Red Nucleus]] (LLC.MM.RD) || [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]] -> [[BrainRegionLLC_MM_RD|LLC.MM.RD]]||[http://openagrosrl.com/www/page/292/ Motor neurons control (LT -> RD)]
 |-
-| [[BrainCenterLPC_HT_VBN|Vestibular Nuclei]] (LPC.HT.VBN) || [[BrainRegionLLC_HT_CR_FN|LLC.HT.CR.FN]] -> [[BrainRegionLPC_HT_LVBN|LPC.HT.LVBN]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (FG -> VB, abstract)]
+| [[BrainCenterLPC_HT_VBN|Vestibular Nuclei]] (LPC.HT.VBN) || [[BrainRegionLRC_HT_CR_FG|LRC.HT.CR.FG]] -> [[BrainRegionLPC_HT_LVBN|LPC.HT.LVBN]]||[http://instruct.uwo.ca/anatomy/530/cblm.htm Cerebellum functional divisions (FG -> VB, abstract)]
 |-
-| [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]] (MM.REF) || [[BrainRegionLLC_HT_CR_FN|LLC.HT.CR.FN]] -> [[BrainRegionLRC_MM_PT_PR|LRC.MM.PT.PR]]||(unknown reference)
+| [[BrainCenterMM_REF|Reflexes Nuclei of Midbrain Mesencephalon]] (MM.REF) || [[BrainRegionLLC_HT_BPN|LLC.HT.BPN]] -> [[BrainRegionLRC_MM_SC_INT|LRC.MM.SC.INT]]||(unknown reference)
 |-
 | [[BrainCenterNC_AL_LPFC|Lateral Prefrontal Cortex]] (NC.AL.LPFC) || [[BrainRegionLLC_HT_CR_DN|LLC.HT.CR.DN]] -> [[BrainRegionNDM_NC_AL_DLPFCL|NDM.NC.AL.DLPFCL]]||(unknown reference)
 |}

Difference between revisions of "BrainCenterLLC HT CRC"

Revision as of 10:06, 10 July 2016

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