Revision as of 10:51, 16 June 2015

Peripheral Brain Research

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This page is intended to create model of peripheral part of biological human brain. It contain muscles, nerves, spinal cord nuclei, cranial nerve nuclei and linked upper brain regions.

Peripheral Brain Details

See also:

• Human Nerves
• Human Muscles
• Spinal Cord

INNER REGIONS

(generated)

• nucleus*: nucleus:
• Autonomic Nuclei
  • ISL: Inferior Salivatory Nucleus,LAC.HM.SAL.ISL - facilitate digestion - produce watery saliva (preganglionic parasympathetic nucleus; project to otic ganglion to parotid and lingual (von Ebner) salivatory glands; posterior pulmonary plexus - motor fibers are derived from inferior salivatory nucleus; glossopharyngeal nerve); TRACTS={}
  • SSL: Superior Salivatory Nucleus,LAC.HM.SAL.SSL - facilitate respiration - produce thiker saliva (preganglionic parasympathetic nucleus; project to submaxillary (submandibular) ganglion to submandibular/sublingual salivatory glands; to sphenopalatine ganglion to superior maxillary nerve as vasodilator and secretory fibers to the mucous membrane of the nose, soft palate, tonsils, uvula, roof of the mouth, upper lips and gums, parotid and orbital glands; facial nerve); TRACTS={}
  • VGN: Vagus Nucleus,LAC.HM.VGN - Parasympathetic vagal functions in the gastrointestinal tract, lungs (Dorsal Motor Nucleus, Cardioinhibitory Center; preganglionic nucleus); TRACTS={}
  • EWN: Edinger-Westphal Nucleus,LAC.MM.EWN - Change Eye Pupil (Parasympathetic nucleus, parvocellular extention of OCN); TRACTS={}
  • CSC: Ciliospinal Center,LAC.SC.IZ.CSC - Control of iris dilator muscle (Budge's Center, intermediolateral cell column); TRACTS={}
  • IML: Intermediolateral Nucleus,LAC.SC.IZ.IML - Mediate entire sympathetic innervation of body (from Lamina VII, visceral sensory); TRACTS={}
  • SPS: Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS - parasympathetic impulses pass via postganglionic fibers to the urinary bladder, erectile tissues, and the smooth muscles and glands in the colon and rectum (from Lamina VII, visceral parasympathetic); TRACTS={}
• Cranial Mechanoreception and Proprioception
  • COND: Dorsal Cochlear Nucleus,LPC.HM.DCOCH - Analyzes quality of sound, picks apart tiny frequency differences between close sounds; TRACTS={}
  • SOL: Solitary Nucleus,LPC.HM.SOL - Carry taste buds, thoracic and abdominal viscera (c.n. VII, IX, X); TRACTS={spinosolitary tract}
  • CONV: Ventral Cochlear Nucleus,LPC.HM.VCOCH - determine direction sound came from, time-sensitive localization; TRACTS={}
  • PTR: Principal Trigeminal Nucleus,LPC.HP.PTP.PTR - Facial Somatic Sensations (Upper, maxillary, ophthalmic); TRACTS={dorsal trigeminal tract}
• Cranial Motor
  • AMB: Ambiguus Nucleus,LPC.HM.AMB - Control muscles of the soft palate, pharynx, and larnyx (On par with VGM, speech; speech and swallowing); TRACTS={corticobulbar tract}
  • HYG: Hypoglossal Motor Nucleus,LPC.HM.HYG - Control of tongue; TRACTS={corticobulbar tract}
  • ABD: Abducens Nucleus,LPC.HP.ABD - Conjugated movements of both eyes (Motoneurons - to muscle, interneurons - to OCN); TRACTS={}
  • FCM: Facial Motor Nucleus,LPC.HP.FCM - Control of face (Pons); TRACTS={corticobulbar tract}
  • TRM: Trigeminal Motor Nucleus,LPC.HP.PTP.TRM - Muscles of first branchial arch (Pontine Nuclei, lower face and jaw control, Motor Nucleus of V n.); TRACTS={corticobulbar tract}
  • OCM: Oculomotor Nucleus,LPC.MM.OCN - Change Eye Direction (Muscle nucleus); TRACTS={}
  • TRH: Trochlear Nucleus,LPC.MM.TRH - Control superior oblique muscles of eyes (Muscle nucleus, change eye direction); TRACTS={}
  • RAM: Retroambigualis Nucleus,LRC.HM.RA - Groups of premotor interneurons producing detailed motor actions (Different combination of activation of these premotor neurons determines vocalization, vomiting, coughing, sneezing, mating posture, or child delivery; ventral respiratory group); TRACTS={}
• Cranial Pain and Temperature
  • PE5: Peritrigeminal Nucleus,LAC.HM.TGM.PE5 - Thermoregulation (Project to thermosensitive neurons of medial preoptic area); TRACTS={}
  • STR: Spinal Trigeminal Nucleus,LPC.HM.TGM.STR - Discriminative sensation and light touch of face, conscious proprioception (Pontine Nuclei, part of cranial nerve nuclei, ear); TRACTS={anterior trigeminothalamic tract}
  • PA5: Paratrigeminal Nucleus,LRC.HM.TGM.PA5 - Orofacial nociceptive sensory processing (Somatosensory reflex, site for nociceptive inputs from sciatic innervation field); TRACTS={}
• Spinal Lateral Motor Nuclei (distal muscles motor neurons)
  • PLN: Posterolateral Nucleus,LPC.SC.VH.PL - Innervation of limb muscles (Upper and lower proximal muscles); TRACTS={lateral corticospinal tract; rubrospinal tract}
  • RPL: Retroposterolateral Nucleus,LPC.SC.VH.RPL - Innervation of limbs muscles (Fingers); TRACTS={lateral corticospinal tract; rubrospinal tract}
  • SAN: Spinal Accessory Nucleus,LPC.SC.VH.SAN - Control of neck (Rotate head, continuus from AMB); TRACTS={corticobulbar tract}
  • VLN: Ventrolateral Nucleus,LPC.SC.VH.VL - Innervation of limb muscles (Upper and lower); TRACTS={anterior corticospinal tract}
• Spinal Mechanoreception and Proprioception
  • CCN: Central Cervical Nucleus,LLC.SC.IZ.CCV - Coordinate voluntary movements, maintain balance, and learn motor skills (Receive neck and vestibular input and project to CR and vestibular nuclei); TRACTS={rostral spinocerebellar tract; spinoolivary tract; spinovestibular tract}
  • ACN: Accessory Cuneate Nucleus,LPC.HM.ACU - receives input from cervical spinal nerves and transmits that information to cerebellum (upper extremity equivalent of Clarke's column); TRACTS={cuneocerebellar tract}
  • CUN: Cuneate Nucleus,LPC.HM.CU - Carry fine touch and proprioceptive information from upper body; TRACTS={fasciculus cuneatus tract; tract of Lissauer}
  • GRN: Gracile Nucleus,LPC.HM.GR - Carry epicritic, kinesthetic, and conscious proprioceptive information from lower body; TRACTS={fasciculus gracilis tract; tract of Lissauer}
  • CBN: Centrobasalis Nucleus,LPC.SC.IZ.CBS - Unconscious proprioception to CR (Upper extremity, relay motor feedback to CR, major site of termination for dorsal root fibers); TRACTS={}
  • IMM: Intermediomedial Nucleus,LPC.SC.IZ.IMM - Visceral sensory (ventral spinocerebellar tract; to vermis); TRACTS={spinomedulloreticular tract; spinopontoreticular tract; ventral spinocerebellar tract}
  • LCN: Lateral Cervical Nucleus,LPC.SC.LH.LCV - Relay Low-threshold Mechanoreceptors to CR (From Lamina V); TRACTS={spinocervical tract}
  • CLN: Clarke Nucleus,LPC.SC.PH.CL - Unconscious Proprioception (To CR); TRACTS={dorsal spinocerebellar tract}
• Spinal Medial Motor Nuclei (axial muscles motor neurons)
  • ONN: Onuf's Nucleus,LPC.SC.VH.ONF - Maintenance of urination and defecation, muscular contraction during orgasm (From Barrington's Nucleus); TRACTS={}
  • PHN: Phrenic Nucleus,LPC.SC.VH.PHR - Innervation of diaphragm (Projections from Nucleus Solitarius); TRACTS={}
  • PMN: Posteromedial Nucleus,LPC.SC.VH.PM - Innervation of trunk muscles (Upper and lower); TRACTS={lateral corticospinal tract; rubrospinal tract}
  • VMN: Ventromedial Nucleus,LPC.SC.VH.VM - Innervation of trunk muscles (Upper and lower); TRACTS={anterior corticospinal tract}
• Spinal Pain and Temperature
  • DCN: Dorsal Commissural Nucleus,LAC.SC.CC.DCN - Relay of sensory information from pelvic viscera (Includes nociception); TRACTS={}
  • LSN: Lateral Spinal Nucleus,LAC.SC.LH.LSN - Integrate autonomic and homeostatic functions (Projects to HT and lateral globus pallidus; integrative nucleus for autonomic and homeostatic functions, and related motivational and affective responses to autonomic function); TRACTS={spinohypothalamic tract; spinosolitary tract; tract of Lissauer}
  • LMG: Lower Marginal Nucleus,LPC.SC.PH.LMG - Relay information related to pain and temperature sensation - T7-T12,L1-L5,S1-S5,CX; TRACTS={lateral spinothalamic tract; spinomesencephalic tract; tract of Lissauer}
  • LSG: Lower Substantia Gelatinosa,LPC.SC.PH.LSG - Relay for C-fibers of slowly conducting, poorly localized pain sensation - T7-T12,L1-L5,S1-S5,CX; TRACTS={anterior spinothalamic tract; lateral spinothalamic tract}
  • NPR: Proprius Nucleus,LPC.SC.PH.NP - Relay light touch, pain and temperature information (With Clarke's Nucleus sensing fine touch and proprioception); TRACTS={spinocervical tract; spinoolivary tract; spinotectal tract}
  • UMG: Upper Marginal Nucleus,LPC.SC.PH.UMG - Relay information related to pain and temperature sensation - C1-C8,T1-T6; TRACTS={lateral spinothalamic tract; spinomesencephalic tract; tract of Lissauer}
  • USG: Upper Substantia Gelatinosa,LPC.SC.PH.USG - Relay for C-fibers of slowly conducting, poorly localized pain sensation - C1-C8,T1-T6; TRACTS={anterior spinothalamic tract; lateral spinothalamic tract}

Peripheral Brain Connectivity

LINKED SENSORY REGIONS

(generated)

• Forebrain Diencephalon
  • Hypothalamus,HTA.FD.HT
    • Anterior Hypothalamus Area,HTA.FD.HT.AHT
      • Chiasmatic Area,HTA.FD.HT.CHS
        • Supraoptic Nucleus,LAC.FD.HT.SO: Blood volume or blood pressure, vasopressin release; TRACTS={spinohypothalamic tract}
        • Suprachiasmatic Nucleus,LAC.FD.HT.SCN: Regulate the circadian cycle, 24-hour rhythms; TRACTS={spinohypothalamic tract}
      • Tuberal Area,HTA.FD.HT.TUB
        • Anterior Hypothalamic Nucleus,LAC.FD.HT.AH: Thermoregulation, panting, sweating; TRACTS={spinohypothalamic tract}
    • Posterior Hypothalamic Area,HTA.FD.HT.POS: Blood pressure, pupillary dilation
      • Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM: Blood pressure, heart rate; TRACTS={spinohypothalamic tract}
    • Lateral Hypothalamic Area,HTA.FD.HT.LT: Thirst and hunger; TRACTS={spinohypothalamic tract}
  • Thalamus,FD.TH
    • Intralaminar and Midline Nuclei of Thalamus,BGA.FD.TH.IML
      • Intralaminar Nuclear Group of Thalamus,BGA.FD.TH.IL: Projects from SC LVII,LVIII and Spinal Trigeminal Nucleus to striatum
        • Caudal Intralaminar Nucleus of Thalamus,FEC.FD.TH.CIL: Stimulate memory-guided response
          • Parafascicular Nucleus of Thalamus,FEC.FD.TH.PF: Stimulation of acetylcholine release in dorsal striata; TRACTS={dorsal trigeminal tract}
    • Mediodorsal Nucleus of Thalamus,FCA.FD.TH.MD: Attention, planning, organization, abstract thinking, multi-tasking, and active memory; TRACTS={dorsal trigeminal tract; lateral spinothalamic tract}
    • Ventral Thalamus,FD.TH.VTH
      • Ventral Posterior Nucleus,SMA.FD.TH.VP
        • Ventral Posteroinferior Nucleus,NSA.FD.TH.VPI: Relays pain and temperature from body to insula; TRACTS={dorsal trigeminal tract; lateral spinothalamic tract}
        • Ventral Posterolateral Nucleus,NSA.FD.TH.VPL: Relays somatic information from body to S1; TRACTS={anterior spinothalamic tract; fasciculus cuneatus tract; fasciculus gracilis tract; spinocervical tract; tract of Lissauer}
        • Ventral Posteromedial Nucleus,NSA.FD.TH.VPM: Relays somatic information from face to S1; TRACTS={anterior trigeminothalamic tract; fasciculus cuneatus tract; tract of Lissauer}
• Hindbrain Myelencephalon
  • Inferior Olivary Nucleus,LLC.HM.IO: Proprioception Relay from Spinal Cord to Cerebellum; TRACTS={spinoolivary tract}
  • Medullary Reticular Formation,HM.RF
    • Medullary Reticular Formation, Medial Column,HM.RF.MED
      • Central Medullary Reticular Nucleus,LRC.HM.RF.MED: Somatic motor control, cardiovascular control, pain modulation, sleep and consciousness, habituation; TRACTS={spinomedulloreticular tract}
• Hindbrain Metencephalon
  • Cerebellum,LLC.HP.CR: Motor coordination; TRACTS={cuneocerebellar tract; dorsal spinocerebellar tract; rostral spinocerebellar tract; ventral spinocerebellar tract}
  • Pontine Reticular Formation,HP.RF
    • Pontine Reticular Formation, Medial Column,HP.RF.MED; TRACTS={spinopontoreticular tract}
    • Pontine Reticular Formation, Lateral Column,HP.RF.LAT
      • Parabrachial Nucleus,LPC.HP.PB: Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception; TRACTS={spinosolitary tract}
  • Vestibular Nucleus,LPC.HP.VBN: Equilibrium, Postural Reflexes
    • Inferior Vestibular Nuclei,LPC.HP.IVBN: maintain balance, coordinating postural adjustments; TRACTS={spinovestibular tract}
• Midbrain Mesencephalon
  • Reflexes Nuclei of Midbrain Mesencephalon,MM.REF
    • Visual Reflexes Nuclei of Midbrain Mesencephalon,MM.REF.VIS
      • Superior Colliculus,MM.SC: Direct behavioral responses toward specific points in egocentric space, induce saccadic eye movement
        • Deep Superior Colliculus,LRC.MM.SC.DEEP: Head and eye attention to non-visual stimuli; TRACTS={spinotectal tract}
  • Periaqueductal Gray Matter,LMC.MM.PAG: Descending modulation of pain and in defensive behaviour; TRACTS={spinocervical tract; spinomesencephalic tract}

LINKED MOTOR REGIONS

(generated)

• Cortex
  • Anterior Lobe,NC.LOBE.ANT
    • Motor Cortex,NMA.NC.MC: Execution of required voluntary movements; TRACTS={corticobulbar tract; lateral corticospinal tract}
    • Premotor Cortex,NC.PMC: Selection of appropriate motor plans for voluntary movements
      • Dorsal Premotor Cortex,MCA.NC.DPMC
        • Dorsal Caudal Premotor Cortex,NMA.NC.PMC.F2: Guiding reaching; TRACTS={anterior corticospinal tract}
    • Supplementary Motor Cortex,NMA.NC.SMC: Process sequences of movements and coordinate bilateral movements
      • Supplementary Motor Area,NMA.NC.SMC.F3: Movement execution; Numerical and verbal mental-operation tasks; TRACTS={anterior corticospinal tract}
• Midbrain Mesencephalon
  • Red Nucleus,LLC.MM.RD: Motor coordination; TRACTS={rubrospinal tract}

LINKED RECIPROCAL REGIONS

(generated)

LINKED GANGLIA

(generated)

• Peripheral Nervous System
  • Sensory Ganglia,PN.SG
    • Trigeminal Ganglion,LPC.PN.SG.TRG: Integration of external auditory meatus (auricular branch), cranial meninges (meningeal branch), and external surface of tympanic membrane; TRACTS={anterior trigeminothalamic tract; dorsal trigeminal tract}
    • Geniculate Ganglion,LPC.PN.SG.GNG: Trophic support for survival; TRACTS={anterior trigeminothalamic tract}
    • Jugular Ganglion,LPC.PN.SG.JUG: Integration of external auditory meatus (auricular branch), cranial meninges (meningeal branch), and external surface of tympanic membrane; TRACTS={anterior trigeminothalamic tract}
    • Nodose Ganglion,LPC.PN.SG.NOD: Integration of afferent signaling from viscera; TRACTS={anterior trigeminothalamic tract}
    • Dorsal Root Ganglion,AVA.PN.SG.DRG: Integration of afferent signaling from somatic viscera
      • Upper Dorsal Root Ganglion,LPC.PN.SG.UDRG: Integration of afferent signaling from cervical and upper thoracic somatic and viscera; TRACTS={anterior spinothalamic tract; cuneocerebellar tract; dorsal spinocerebellar tract; fasciculus cuneatus tract; lateral spinothalamic tract; rostral spinocerebellar tract; spinohypothalamic tract; spinomedulloreticular tract; spinomesencephalic tract; spinoolivary tract; spinopontoreticular tract; spinosolitary tract; spinotectal tract; spinovestibular tract; tract of Lissauer; ventral spinocerebellar tract}
      • Lower Dorsal Root Ganglion,LPC.PN.SG.LDRG: Integration of afferent signaling from lower thoracic and lumbosacral somatic and viscera; TRACTS={anterior spinothalamic tract; dorsal spinocerebellar tract; fasciculus gracilis tract; spinocervical tract; spinohypothalamic tract; spinomedulloreticular tract; spinomesencephalic tract; spinopontoreticular tract; spinosolitary tract; tract of Lissauer; ventral spinocerebellar tract}