Difference between revisions of "BrainRegionLMC MM VTA"

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'''Component items''':
 
'''Component items''':
−
* '''Medial Ventral Tegmental Area'''
+
* '''Ventral Tegmental Nucleus''' ('''LMC.MM.VTG'''): moderates hippocampal-driven rhythmic firing frequency in medial mammillary
 
* '''Parabrachial Pigmented Area'''
 
* '''Parabrachial Pigmented Area'''
 
* '''Paranigral Nucleus'''
 
* '''Paranigral Nucleus'''
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| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
 
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
 
|-
 
|-
−
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference)
+
| [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] || Lateral Habenula Medial Part || excitatory-glu || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)]
 +
|-
 +
|  || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference)
 
|-
 
|-
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || inhibitory-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)]
 
| [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || inhibitory-gaba || [http://neurowiki2012.wikispaces.com/Presynaptic+Mechanisms+of+Synaptic+Plasticity Reward circuit of human brain (NACC -> VTA, abstract)]
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|  || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VPAL -> VTA, abstract)]
 
|  || [[BrainRegionFEC_FT_VP_VM|FEC.FT.VP.VM]] || Ventral Pallidum Ventromedial || inhibitory-gaba || [http://www.impulsecontroldisorders.org/html/cravings.html Craving (VPAL -> VTA, abstract)]
 
|-
 
|-
−
|  || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (RMTG -> VTA)]
+
|  || [[BrainRegionFEC_HT_PPN_IPD|FEC.HT.PPN.IPD]] || Interpeduncular Nucleus || modulatory-ach || [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> VTA)]
 
|-
 
|-
−
| [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_TG_VTG|LMC.HT.TG.VTG]] || Ventral Tegmental Nucleus || excitatory-glu || (unknown reference)
+
| || [[BrainRegionFEC_HT_PPN_RMTG|FEC.HT.PPN.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (RMTG -> VTA)]
 
|}
 
|}
  
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<img src="http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg" alt="unavailable">
 
<img src="http://img.springerimages.com/Images/Springer/PUB=Springer-Verlag-Berlin-Heidelberg/JOU=00359/VOL=2005.191/ISU=3/ART=2004_565/MediaObjects/WATER_s00359-004-0565-9fhc1.jpg" alt="unavailable">
 +
 +
* [http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg Both LHb and MHb control the dopaminergic and serotonergic systems] - see [http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Reference]
 +
 +
<img src="http://www.nature.com/neuro/journal/v17/n9/images/nn.3779-F2.jpg" alt="unavailable">
  
 
* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
 
* [http://www.scholarpedia.org/w/images/thumb/2/2d/Hb-connections-small.jpg/800px-Hb-connections-small.jpg Habenula Connections] - see [http://www.scholarpedia.org/article/Habenula Reference]
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* http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
 
* http://www.nature.com/nrn/journal/v5/n1/fig_tab/nrn1299_F4.html
 
* http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
 
* http://www.springerimages.com/Images/LifeSciences/1-10.1007_s00359-004-0565-9-0
 +
* http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html
 
* http://www.scholarpedia.org/article/Habenula
 
* http://www.scholarpedia.org/article/Habenula

Revision as of 20:50, 20 August 2015

Ventral Tegmental Area

@@Home -> BiologicalLifeResearch -> BrainAreaLMC -> BrainRegionLMC_MM_VTA

This page covers biological details of component Ventral Tegmental Area. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Midbrain Mesencephalon -> Ventral Tegmental Area (LMC.MM.VTA) (see Mind Maps)
  • Type: nucleus
  • Brain area: Lower Brain - Modulatory Contol Area
  • Role: relay
  • Function: Respond to novel stimuli, unexpected rewards, and reward predictive sensory cues

(generated)

Components

(generated)


Component items:

  • Ventral Tegmental Nucleus (LMC.MM.VTG): moderates hippocampal-driven rhythmic firing frequency in medial mammillary
  • Parabrachial Pigmented Area
  • Paranigral Nucleus
  • Parafasciculus Retroflexus Area

Connectivity

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LMC.MM.VTA.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)
FAM.FT.BNST Bed Nucleus of Stria Terminalis excitatory-glu (unknown reference)
FEC FEC.FT.ACC.CORE Nucleus Accumbens Core inhibitory-gaba Reward circuit of human brain (NACC -> VTA, abstract)
FEC.FT.VP.VM Ventral Pallidum Ventromedial inhibitory-gaba Craving (VPAL -> VTA, abstract)
FEC.HT.PPN.IPD Interpeduncular Nucleus modulatory-ach Both LHb and MHb control the dopaminergic and serotonergic systems (IPN -> VTA)
FEC.HT.PPN.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba Amygdala and its network (RMTG -> VTA)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FT.AM.CEC Central Amygdaloid Nucleus, capsular subdivision modulatory-da Reward circuit of human brain (VTA -> AM, abstract)
FEC FEC.FT.ACC.SH Nucleus Accumbens Shell modulatory-da Craving (VTA -> NACC, abstract)
FMM FMM.FD.MB.MMB Medial Mammillary Nucleus modulatory-da Mammillary bodies: two memory systems in one (VTN -> MMB)
FMM.FT.HC.CA1D Distal CA1 of Hippocampus modulatory-da Reward circuit of human brain (VTA -> HC, abstract)
FMM.NC.PH.LEC Lateral Entorhinal Cortex modulatory-da Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)
LAC LAC.FD.HT.PO Preoptic Nucleus modulatory-da Physiology and pathophysiology of lower urinary tract (VTA -> MPOA)
LAC.FD.HT.PRM Premammillary Nucleus modulatory-da (unknown reference)
LAC.FD.HT.PV Paraventricular Nucleus modulatory-da Physiology and pathophysiology of lower urinary tract (VTA -> PVN)
NDM NDM.NC.AL.DACG Dorsal Anterior Cingulate Area modulatory-da (unknown reference)
NDM.NC.AL.FPC Lateral Frontopolar Cortex modulatory-da Amygdala and its network (VTA -> MPFC, abstract)

Thirdparty Circuits

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References

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