BrainCenterNC INS
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Insular Cortex
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This page covers biological details of component group Insular Cortex. Component group is part of aHuman target integrated biological model.
- Top-down path to center: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) (see Mind Maps)
- Function: Visceral representation, pain, habits
- Notes to function: Interoception, merges tactile and auditory streams
(generated)
Components
(generated)
Component items:
- Posterior Insular Cortex (NCP.NC.INS.PIC): Awareness and sensation of pain
- Anterior Insular Cortex (NCP.NC.INS.AIC): Risky and moral decision making, articulation
- Anterior Temporal Lobe (NCP.NC.INS.HR): Relaying blood pressure and blood chemistry information to brain
- Peripaleocortical Claustral (NCP.NC.INS.PPC): Relays proprioception
Connectivity
(generated)
Internal Regions Connections:
| Source Region | Target Region | Reference |
| Posterior Insular Cortex (NCP.NC.INS.PIC) | Anterior Insular Cortex (NCP.NC.INS.AIC) | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
| Peripaleocortical Claustral (NCP.NC.INS.PPC) | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
External Connections:
External Inbound Center Connections:
| Source Center | Sample Link | Reference |
| Central Extended Amygdala (FAM.FT.CEAM) | FAM.FT.EPF -> NCP.NC.INS.AIC | Gustatory sensory system of rat and macaque (EnP -> Iav, abstract) |
| Cognitive Thalamus (FD.TH.CR) | NCP.FD.TH.MDC -> NCP.NC.INS.AIC | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) |
| Sensory Thalamus (FD.TH.SR) | NSA.FD.TH.VPL -> NCP.NC.INS.HR | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) |
| Pontine Reticular Formation (HT.RF) | LPC.HT.PRF.PB -> NCP.NC.INS.PIC | Gustatory sensory system of rat and macaque (PB -> Gud, abstract) |
| Rhinal Cortex (NC.PHA.RH) | NSA.NC.PH.PIR -> NCP.NC.INS.AIC | Gustatory sensory system of rat and macaque (PiR -> Iav, abstract) |
| Superior Parietal Lobule (NC.SPL) | NPE.NC.SPL.SA -> NCP.NC.INS.PIC | (unknown reference) |
| Superior Temporal Gyrus (NC.STG) | NCP.NC.TPC -> NCP.NC.INS.AIC | Directed Effort Network (tPole -> Insula, abstract) |
External Outbound Center Connections:
| Target Center | Sample Link | Reference |
| Amygdala (FAM.FT.AM) | NCP.NC.INS.PIC -> FAM.FT.AM.BM | (unknown reference) |
| Retrosubicular Area (FMM.NC.PHA.RS) | NCP.NC.INS.PPC -> FMM.NC.PH.PRS | (unknown reference) |
| Anterior Cingulate Area (NC.ACG) | NCP.NC.INS.AIC -> NDM.NC.AL.VACG | Amygdalar disruption of prefrontal cortex (INS -> ACG, abstract) |
| Lateral Prefrontal Cortex (NC.AL.LPFC) | NCP.NC.INS.AIC -> NDM.NC.AL.IPG | Directed Effort Network (Insula -> fPole, abstract) |
| Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) | NCP.NC.INS.PPC -> NDM.NC.AL.FPC | Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract) |
| Rhinal Cortex (NC.PHA.RH) | NCP.NC.INS.AIC -> FMM.NC.PH.PER | Gustatory sensory system of rat and macaque (Iav -> PrC, abstract) |
