BrainRegionNDM NC AL VMPFC
Ventromedial Prefrontal Cortex
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This page covers biological details of component Ventromedial Prefrontal Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Medial Prefrontal Cortex (NC.AL.MPFC) -> Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC) (see Mind Maps)
- Type: cortex
- Brain area: Neocortical Brain - Decision Making Area
- Brodmann ID: 11
- Role: cortex.generic
- Function: Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment
- Notes to function: lower MPFC, primary connections to limbic and sensory cortices; Reward mediated behaviours
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| FAM | FAM.FT.SEP.DBB | Diagonal Band of Broca | inhibitory-gaba | (unknown reference) |
| FMM | FMM.FT.HC.CA1D | Distal CA1 of Hippocampus | excitatory-glu | Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract) |
| NDM | NDM.FD.TH.PV | Paraventricular Nucleus of Thalamus | excitatory-glu | Saccadic Vision (Thalamus -> FrontalCortex, abstract) |
| NDM.NC.AL.DLPFCR | Rostral Mid-Dorsolateral Prefrontal Cortex | feedforward-glu | Fear regulation (dlPFC -> vmPFC, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FAM | FAM.FT.AM.ITC | Intercalated Amygdaloid Nuclei | excitatory-glu | (unknown reference) |
| FAM.FT.AM.LADL | Dorsolateral Amygdaloid Nucleus | excitatory-glu | (unknown reference) |
Thirdparty Circuits
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- Fear regulation - see Reference
map: B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (Parvicellular Basal Amygdaloid Nucleus (FAM.FT.AM.BP), Magnocellular Basal Amygdaloid Nucleus (FAM.FT.AM.BM)), CE=Central Amygdala,FAM.FT.AM.CEA (Central Amygdaloid Nucleus, capsular subdivision (FAM.FT.AM.CEC), Central Amygdaloid Nucleus, lateral subdivision (FAM.FT.AM.CEL), Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM)), Hippocampus=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), Hypothalamus=Hypothalamus,FD.HT, ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC, LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC
References
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