BrainRegionLPC SC VH ONF
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Onuf's Nucleus
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This page covers biological details of component Onuf's Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Spinal Cord -> Anterior/Ventral Horn (SC.VH) -> Lamina IX (SC.VH.L9) -> Onuf's Nucleus (LPC.SC.VH.ONF) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Peripheral Control Area (LPC)
- Area circuit: Control Body Special Flexors (MBFS)
- Role: flexor.nucleus
- Function: Maintenance of urination and defecation, muscular contraction during orgasm
- Notes to function:
- From Barrington's Nucleus
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| LAC | LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | uncertain | (unknown reference) |
| LAC.HT.BR | Barrington's Nucleus | excitatory-glu | uncertain | Schematic overview of spinobulbospinal micturition reflex pathway (BAR -> ONF) | |
| LRC | LRC.HL.RA | Retroambigualis Nucleus | excitatory-glu | uncertain | (unknown reference) |
| NMA | NMA.NC.MC | Motor Cortex | excitatory-glu | uncertain | Cerebellum functional divisions (CTX -> SCM, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| TEA | TARGET.TEA.GENITALIA | Genitalia | bulbospongiosus-muscle | (none) | (unknown reference) |
| TARGET.TEA.RECTUM | Rectum | corrugator-cutis-ani-muscle | (none) | (unknown reference) | |
| TARGET.TEA.URETER | Ureter | external-urethral-sphincter-female | (none) | (unknown reference) |
Thirdparty Circuits
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- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Schematic overview of spinobulbospinal micturition reflex pathway - see Reference (CM.BARRINGTON)
BAR=Barrington's Nucleus,LAC.HT.BR IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML ONF=Onuf's Nucleus,LPC.SC.VH.ONF PAG=Periaqueductal Gray Matter,LMC.MM.PAG PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS
References
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