BrainRegionLRC MM CJ
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Cajal Nucleus
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This page covers biological details of component Cajal Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Midbrain Mesencephalon -> Reflexes Nuclei of Midbrain Mesencephalon (MM.REF) -> Visual Reflexes Nuclei of Midbrain Mesencephalon (MM.REF.VIS) -> Supraoculomotor Area (VBA.MM.SOA) -> Cajal Nucleus (LRC.MM.CJ) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Motor Reflex Area (LRC)
- Area circuit: Frontal Visual Reflexes (LRF)
- Role: subcortical.motor.flexor
- Function: Integration of head and eye movements, controls downward vertical gaze
- Comments: Relay of extrapyramidal control for automatic movements
- Notes to function:
- Projects to CN3, CN4 nuclei, rotation of body about its long axis, Project to vestibular nuclei
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| LPC | LPC.HL.VCOCH | Ventral Cochlear Nucleus | excitatory-glu | uncertain | (unknown reference) |
| LRC | LRC.MM.SC.DEEP | Deep Superior Colliculus | excitatory-glu | uncertain | Summary of eye movement control (SC -> riMLF, abstract) |
| NPE | NPE.NC.IPS.LIP | Lateral Intraparietal Sulcus | excitatory-glu | uncertain | Vision Components (VAC -> SOA, abstract) |
| NPE.NC.OCC.V3D | Dorsal Associative Visual Cortex | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (VAC -> SupraOculomotor, abstract) | |
| NPE.NC.PMC.AFEF | Anterior Frontal Eye Field | excitatory-glu | uncertain | Summary of eye movement control (FEF -> riMLF, abstract) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Role | Reference |
| LPC | LPC.MM.OCN | Oculomotor Nucleus | excitatory-glu | uncertain | Eye blink reflex and pupillary light reflex (SupraOculomotor -> Oculomotor, abstract) |
| LPC.MM.TRH | Trochlear Nucleus | excitatory-glu | uncertain | (unknown reference) |
Thirdparty Circuits
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- Eye blink reflex and pupillary light reflex - see Reference (CP.SACCADIC-MOTOR-CONTROL)
Abducens=Abducens Nucleus,LPC.HT.ABD Ciliary=Ciliary Ganglion,LAC.PN.PSYM.CLG EWN=Edinger-Westphal Nucleus,LAC.MM.EWN EYE=Eye,TARGET.TSA.EYE Facial=Facial Motor Nucleus,LPC.HT.FCM Oculomotor=Oculomotor Nucleus,LPC.MM.OCN Pretectum=Pretectum,MM.PT (see Reflexes Nuclei of Midbrain Mesencephalon) PrincipalTrigeminal=Principal Trigeminal Nucleus,LPC.HT.PN.PTR RF=Pontine Reticular Formation,HT.RF SpinalTrigeminal=Spinal Trigeminal Nucleus,LPC.HL.TGS.STR SupraOculomotor=Supraoculomotor Area,VBA.MM.SOA (see Reflexes Nuclei of Midbrain Mesencephalon) VAC=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe)
- Saccades and smooth movements (unknown reference) (CP.SACCADIC-VOLUNTARY-AND-PURSUIT)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex) DLPN=Oral Pontine Reticular Nucleus,LRC.HT.PRF.RPO Extrastriate=Associative Visual Cortex,NPE.NC.OCC.V3 (see Occipital Lobe) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PPC=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SN=Substantia Nigra,FEC.FT.SN (see Basal Ganglia) Striate=Primary Visual Cortex,NSA.NC.OCC.V1 TEF=Inferotemporal Area,NSA.NC.IT VGC=Cajal Nucleus,LRC.MM.CJ Vestibular=Lateral Vestibular Nucleus,LPC.HT.LVBN
- Summary of eye movement control - see Reference (CP.EYE-FIELDS)
DLPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (see Lateral Prefrontal Cortex) FEF=Frontal Eye Field,NMA.NC.PMC.FEF (see Premotor Cortex) PEF=Posterior Eye Field,NPE.NC.IPS.PEF (see Intraparietal Sulcus) PPRF=Paramedian Pontine Reticular Formation,HT.PRF.PPRF (see Pontine Reticular Formation) SC=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon) SEF=Supplementary Eye Field,NPE.NC.SMC.SEF riMLF=Cajal Nucleus,LRC.MM.CJ
References
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