BrainCenterNC AL OMPFC
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Orbitomedial Prefrontal Cortex
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This page covers biological details of component group Orbitomedial Prefrontal Cortex. Component group is part of aHuman target integrated biological model.
- Top-down path to center: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) (see Mind Maps)
- Function: High-level Motivational Functions
(generated)
Components
(generated)
Component items:
- Orbitofrontal Cortex (NC.AL.OPFC): Personality
- Lateral Frontopolar Cortex (NDM.NC.AL.FPC): Emotion Regulation
- Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFC): Prefrontal associational integration
- Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR): Integral conscious selection of novelty
- Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS): Gustatory and auditory selection of novelty
- Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM): Somatosensory selection of novelty
- Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL): Visual selection of novelty
- Medial Prefrontal Cortex (NC.AL.MPFC): Response Selection
- Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC): Ongoing Extroverted Attention to Select Appropriate Response
- Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC): Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment
Connectivity
(generated)
Internal Regions Connections:
| Source Region | Target Region | Reference |
| Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) | Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR) | Regulation of Social Brain (MPFC -> OFC, abstract) |
| Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM) | Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) | Regulation of Social Brain (MPFC -> OFC, abstract) |
| Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR) | Regulation of Social Brain (MPFC -> OFC, abstract) | |
| Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS) | Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL) | Regulation of Social Brain (MPFC -> OFC, abstract) |
External Connections:
External Inbound Center Connections:
| Source Center | Reference |
| Central Extended Amygdala (FAM.FT.CEAM) | Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract) |
| Septal Nuclei (FAM.FT.SEP) | (unknown reference) |
| Thalamus (FD.TH) | Saccadic Vision (Thalamus -> FrontalCortex, abstract) |
| Hippocampal Formation (FMM.FT.HF) | Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract) |
| Ventral Tegmental Area (LMC.MM.VTA) | Amygdala and its network (VTA -> MPFC, abstract) |
| Lateral Prefrontal Cortex (NC.AL.LPFC) | (unknown reference) |
| Insular Cortex (NC.INS) | Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract) |
| Medial Parietal Lobule (NC.MPL) | Prefrontal Cortex (PFC) in emotional behavior (PCA -> OPFC, abstract) |
| Parietal Operculum (NC.PO) | Global visual system (ParietalCortex -> FrontalCortex, abstract) |
| Superior Parietal Lobule (NC.SPL) | Cortico-Cortical Connectivity (SA -> PFC, abstract) |
External Outbound Center Connections:
| Target Center | Reference |
| Amygdala (FAM.FT.AM) | (unknown reference) |
| Septal Nuclei (FAM.FT.SEP) | (unknown reference) |
| Hypothalamus (FD.HT) | Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract) |
| Thalamus (FD.TH) | (unknown reference) |
| Subthalamus Area (FEC.FD.STA) | (unknown reference) |
| Basal Ganglia (FEC.FT.BG) | Affective basal ganglia circuit (OMPFC -> NACC, abstract) |
| Anterior Cingulate Area (NC.ACG) | (unknown reference) |
| Lateral Prefrontal Cortex (NC.AL.LPFC) | Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract) |
