Difference between revisions of "BrainRegionLAC FD HT SCN"

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<pre style="color: green">Suprachiasmatic Nucleus</pre>
 
<pre style="color: green">Suprachiasmatic Nucleus</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_SCN]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaLAC]] -> [[BrainRegionLAC_FD_HT_SCN]]
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* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> [[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus]] (LAC.FD.HT.SCN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Top-down path to region''': Forebrain Diencephalon -> [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> [[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus]] (LAC.FD.HT.SCN) (see [[OverallMindMaps|Mind Maps]])
 
* '''Type''': nucleus
 
* '''Type''': nucleus
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]]
+
* '''Quality''': L0
* '''Role''': relay
+
* '''Brain area''': [[BrainAreaLAC|Lower Brain - Autonomous Control Area]] (LAC)
 +
* '''Area circuit''': Daily Cycle Autonomic Control (LADC)
 +
* '''Role''': processor.autonomic
 
* '''Function''': Regulate the circadian cycle, 24-hour rhythms
 
* '''Function''': Regulate the circadian cycle, 24-hour rhythms
 
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference'''
+
| '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_RT|LPC.FD.RT]] || Retina || excitatory-glu || [http://www.rci.rutgers.edu/~uzwiak/AnatPhys/Vision.htm Targets of retina neurons (Retina -> HT, abstract)]
+
| [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_FD_RT|LPC.FD.RT]] || Retinal Nucleus || excitatory-glu || uncertain ||[http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Effect of light on pupil diameter (RET -> SCN)]
 
|-
 
|-
| || [[BrainRegionLPC_FD_TH_PV|LPC.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || (unknown reference)
+
| [[BrainAreaNDM|NDM]] || [[BrainRegionNDM_FD_TH_PV|NDM.FD.TH.PV]] || Paraventricular Nucleus of Thalamus || excitatory-glu || uncertain ||(unknown reference)
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference'''
+
| '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference'''
 
|-
 
|-
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> DMN)]
+
| [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> DMN)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_PO|LAC.FD.HT.PO]] || Preoptic Nucleus || excitatory-glu || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)]
+
|  || [[BrainRegionLAC_FD_HT_MPO|LAC.FD.HT.MPO]] || Median Preoptic Nucleus || excitatory-glu || uncertain || [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)]
 
|-
 
|-
|  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionLAC_FD_HT_PV|LAC.FD.HT.PV]] || Paraventricular Nucleus || excitatory-glu || uncertain || [http://www.pnas.org/content/103/32/12150/F7.expansion.html Food-entrainable circadian oscillator (SCN -> PVH)]
 
|-
 
|-
|  || [[BrainRegionLAC_PN_SYM_SCG|LAC.PN.SYM.SCG]] || Superior Cervical Ganglion || excitatory-glu || (unknown reference)
+
|  || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] || Ventrolateral Preoptic Nucleus || excitatory-glu || uncertain || (unknown reference)
 
|-
 
|-
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_PT_NOT|LRC.MM.PT.NOT]] || Nucleus of Optic Tract || excitatory-glu || (unknown reference)
+
| [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_MM_PT_NOT|LRC.MM.PT.NOT]] || Nucleus of Optic Tract || excitatory-glu || uncertain || (unknown reference)
 
|}
 
|}
  
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* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference]
+
* [http://www.pnas.org/content/103/32/12150/F7.large.jpg Food-entrainable circadian oscillator] - see [http://www.pnas.org/content/103/32/12150/F7.expansion.html Reference] (CP.FOOD-OCSILLATOR)
 +
 
 +
DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
NTS=[[BrainRegionLPC_HL_SOL|Solitary Nucleus,LPC.HL.SOL]]
 +
PBN=[[BrainRegionLPC_HT_PRF_PB|Parabrachial Nucleus,LPC.HT.PRF.PB]]
 +
PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/8f1f58bb00bedda8aee035b59f4b1a61.jpg" alt=alt="unavailable" style="max-width: 100%;" height=300>
 +
 
 +
* [http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png Intrahypothalamic connections important for neural control of food intake and energy balance] - see [http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf Reference] (CL.INTRAHYPOTHALAMIC)
 +
 
 +
AH=[[BrainRegionLAC_FD_HT_AH|Anterior Hypothalamic Nucleus,LAC.FD.HT.AH]]
 +
ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 +
DMN=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
MPOA=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
PA=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SCH=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
SON=[[BrainRegionLAC_FD_HT_SO|Supraoptic Nucleus,LAC.FD.HT.SO]]
 +
VMN=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/812cda92ff47d048aeb22ce670a9a9fb.png" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://www.frontiersin.org/files/Articles/31465/fnint-06-00094-r2/image_m/fnint-06-00094-g002.jpg Effect of light on pupil diameter] - see [http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full Reference] (CP.PUPIL-REFLEX)
 +
 
 +
DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
EW=[[BrainRegionLAC_MM_EWN|Edinger-Westphal Nucleus,LAC.MM.EWN]]
 +
EYE=[[BrainRegionTARGET_TSA_EYE|Eye,TARGET.TSA.EYE]]
 +
GC=[[BrainRegionLAC_PN_PSYM_CLG|Ciliary Ganglion,LAC.PN.PSYM.CLG]]
 +
IML=[[BrainRegionLAC_SC_IZ_CSC|Ciliospinal Center,LAC.SC.IZ.CSC]]
 +
LC=[[BrainRegionLMC_HT_LC|Locus Coeruleus,LMC.HT.LC]]
 +
OPN=[[BrainRegionLRC_MM_PT_PON|Pretectal Olivary Nucleus,LRC.MM.PT.PON]]
 +
PVN=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
RET=[[BrainRegionLPC_FD_RT|Retinal Nucleus,LPC.FD.RT]]
 +
SCG=[[BrainRegionLAC_PN_SYM_SCG|Superior Cervical Ganglion,LAC.PN.SYM.SCG]]
 +
SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/1cde10342c1a8c5667b42d9df87c4f50.jpg" alt=alt="unavailable" style="max-width: 100%;">
 +
 
 +
* [http://www.dana.org/uploadedImages/Images/Content_Images/SenBodyFunc2_PR2007_cont.jpg Eating and sleeping to survive] - see [http://www.dana.org/Publications/ReportDetails.aspx?id=44217 Reference] (CP.DMH-CYCLES)
  
<img src="http://usvn.ahuman.org/svn/ahwiki/images/wiki/research/biomodel/intrahypothalamic.png" alt="unavailable">
+
ARC=[[BrainRegionLAC_FD_HT_AR|Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR]]
 +
DMH=[[BrainRegionLAC_FD_HT_DM|Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM]]
 +
LHA=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]]
 +
MPO=[[BrainRegionLAC_FD_HT_MPO|Median Preoptic Nucleus,LAC.FD.HT.MPO]]
 +
PVH=[[BrainRegionLAC_FD_HT_PV|Paraventricular Nucleus,LAC.FD.HT.PV]]
 +
SCN=[[BrainRegionLAC_FD_HT_SCN|Suprachiasmatic Nucleus,LAC.FD.HT.SCN]]
 +
VLPO=[[BrainRegionLAC_FD_HT_VLPO|Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO]]
 +
VMH=[[BrainRegionLAC_FD_HT_VM|Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM]]
 +
<img src="http://ahuman.org/svn/ahwiki/images/ext/aaf05c2cb0453d5f112754ade7c03956.jpg" alt=alt="unavailable" style="max-width: 100%;">
  
  
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 +
* http://www.pnas.org/content/103/32/12150/F7.expansion.html
 
* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
 
* http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
 +
* http://journal.frontiersin.org/article/10.3389/fnint.2012.00094/full
 +
* http://www.dana.org/Publications/ReportDetails.aspx?id=44217

Latest revision as of 18:28, 28 April 2019

Suprachiasmatic Nucleus

@@Home -> BiologicalLifeResearch -> BrainAreaLAC -> BrainRegionLAC_FD_HT_SCN


This page covers biological details of component Suprachiasmatic Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Chiasmatic Area (LAC.FD.HT.CHS) -> Suprachiasmatic Nucleus (LAC.FD.HT.SCN) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Autonomous Control Area (LAC)
  • Area circuit: Daily Cycle Autonomic Control (LADC)
  • Role: processor.autonomic
  • Function: Regulate the circadian cycle, 24-hour rhythms

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Components

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Component items:

  • Dorsomedial Suprachiasmatic Nucleus
  • Ventrolateral Suprachiasmatic Nucleus
  • Ventral Suprachiasmatic Nucleus

Connectivity

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LAC.FD.HT.SCN.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Role Reference
LPC LPC.FD.RT Retinal Nucleus excitatory-glu uncertain Effect of light on pupil diameter (RET -> SCN)
NDM NDM.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu uncertain (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Role Reference
LAC LAC.FD.HT.DM Dorsomedial Hypothalamic Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> DMN)
LAC.FD.HT.MPO Median Preoptic Nucleus excitatory-glu uncertain Intrahypothalamic connections important for neural control of food intake and energy balance (SCH -> MPOA)
LAC.FD.HT.PV Paraventricular Nucleus excitatory-glu uncertain Food-entrainable circadian oscillator (SCN -> PVH)
LAC.FD.HT.VLPO Ventrolateral Preoptic Nucleus excitatory-glu uncertain (unknown reference)
LRC LRC.MM.PT.NOT Nucleus of Optic Tract excitatory-glu uncertain (unknown reference)

Thirdparty Circuits

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DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
NTS=Solitary Nucleus,LPC.HL.SOL
PBN=Parabrachial Nucleus,LPC.HT.PRF.PB
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH
ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO
PA=Paraventricular Nucleus,LAC.FD.HT.PV
SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
SON=Supraoptic Nucleus,LAC.FD.HT.SO
VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM

DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
EW=Edinger-Westphal Nucleus,LAC.MM.EWN
EYE=Eye,TARGET.TSA.EYE
GC=Ciliary Ganglion,LAC.PN.PSYM.CLG
IML=Ciliospinal Center,LAC.SC.IZ.CSC
LC=Locus Coeruleus,LMC.HT.LC
OPN=Pretectal Olivary Nucleus,LRC.MM.PT.PON
PVN=Paraventricular Nucleus,LAC.FD.HT.PV
RET=Retinal Nucleus,LPC.FD.RT
SCG=Superior Cervical Ganglion,LAC.PN.SYM.SCG
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN

ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM
LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN
MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO
PVH=Paraventricular Nucleus,LAC.FD.HT.PV
SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO
VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM


References

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