BrainRegionLMC HL RP MG

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Raphe Magnus Nucleus

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This page covers biological details of component Raphe Magnus Nucleus. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Hindbrain Myelencephalon -> Medullary Reticular Formation (HL.RF) -> Medullary Reticular Formation, Midline Column (HL.RF.MID) -> Raphe Nuclei of Medulla (LMC.HL.RP) -> Raphe Magnus Nucleus (LMC.HL.RP.MG) (see Mind Maps)
  • Type: nucleus
  • Quality: L0
  • Brain area: Lower Brain - Modulatory Contol Area (LMC)
  • Area circuit: Serotonin - Feelings of Well-Being and Happiness (5HT)
  • Role: processor.autonomic
  • Function: Inhibit head and spinal pain
  • Notes to function:
    • B3, contacts with enkephalenic neurons in substantia gelatinosa

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Components

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  • no child items defined

Connectivity

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LMC.HL.RP.MG.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.LHB.MED Lateral Habenula Medial Part excitatory-glu Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> MRN, abstract)
FEC FEC.HT.TG.IPD Interpeduncular Nucleus modulatory-ach Connectivity map of the habenula (IPN -> Raphe, abstract)
FEC.HT.TG.RMTG Rostromedial Tegmental Nucleus inhibitory-gaba Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> MRN, abstract)
LAC LAC.FD.HT.LTN Lateral Hypothalamic Nucleus excitatory-glu (unknown reference)
LAC.FD.HT.PV Paraventricular Nucleus excitatory-glu (unknown reference)
LMC LMC.MM.PAG Periaqueductal Gray Matter modulatory-enk Connectivity map of the habenula (PAG -> Raphe, abstract)
LRC LRC.MM.SCNF Subcuneiform Nucleus excitatory-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
LPC LPC.SC.PH.LSG Lower Substantia Gelatinosa modulatory-5ht (unknown reference)
LPC.SC.PH.USG Upper Substantia Gelatinosa modulatory-5ht (unknown reference)

Thirdparty Circuits

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  • no circuits defined

References

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  • no references defined