BrainRegionNCP NC INS PIC
Posterior Insular Cortex
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This page covers biological details of component Posterior Insular Cortex. Region is part of aHuman target integrated biological model.
- Top-down path to region: Cerebral Cortex -> Temporal Lobe (NC.LOBE.TEMP) -> Insular Cortex (NC.INS) -> Posterior Insular Cortex (NCP.NC.INS.PIC) (see Mind Maps)
- Type: cortex
- Brain area: Neocortical Brain - Conscious Personality Area
- Brodmann ID: 13
- Role: cortex.sensory.primary
- Function: Awareness and sensation of pain
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Reference |
| LPC | LPC.HT.PRF.PB | Parabrachial Nucleus | excitatory-glu | Gustatory sensory system of rat and macaque (PB -> Gud, abstract) |
| NCP | NCP.FD.TH.VPI | Ventral Posteroinferior Nucleus | excitatory-glu | Pain matrix (TH.VPI -> INS) |
| NCP.FD.TH.VPM | Ventral Posteromedial Nucleus | excitatory-glu | Amygdalar disruption of prefrontal cortex (TH -> INS, abstract) | |
| NCP.NC.SPL.SA | Somatosensory Association Cortex | feedforward-glu | (unknown reference) |
Outbound Region Connections:
| Target Area | Target Region | Target Name | Type | Reference |
| FAM | FAM.FT.AM.BM | Magnocellular Basal Amygdaloid Nucleus | excitatory-glu | Afferent pain pathways (Insula -> AMY, abstract) |
| NCP | NCP.NC.INS.AIC | Anterior Insular Cortex | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
| NCP.NC.INS.PPC | Peripaleocortical Claustral | feedforward-glu | Gustatory sensory system of rat and macaque (Iav -> IadIap, abstract) |
Thirdparty Circuits
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map: EnP=Endopiriform Nucleus,FAM.FT.EPF, Gud=Insular Cortex,NC.INS, Gug=Insular Cortex,NC.INS, HF=Hippocampal Formation,FMM.FT.HF, IadIap=Insular Cortex,NC.INS, Iav=Insular Cortex,NC.INS, NST=Solitary Nucleus,LPC.HL.SOL, PB=Parabrachial Nucleus,LPC.HT.PRF.PB, PiR=Piriform Cortex,NSA.NC.PH.PIR, PrC=Perirhinal Cortex,FMM.NC.PH.PER, VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
map: ACC=Anterior Cingulate Cortex,NC.AL.ACG (Ventral Anterior Cingulate Area (NDM.NC.AL.VACG), Dorsal Anterior Cingulate Area (NDM.NC.AL.DACG), Subgenual Cingulate Cortex (NCP.NC.AL.SGCG)), AMY=Amygdala,FAM.FT.AM, BG=Basal Ganglia,FEC.FT.BG, Cerebellum=Cerebellar Complex,LLC.HT.CRC, Insula=Insular Cortex,NC.INS, PAG=Periaqueductal Gray Matter,LMC.MM.PAG, PB=Parabrachial Nucleus,LPC.HT.PRF.PB, PFC=Prefrontal Cortex,NC.AL.PFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL), Inferior Prefrontal Gyrus (NDM.NC.AL.IPG), Broca's Area Pars Opercularis (NPE.NC.BRA.PO), Broca's Area Pars Triangularis (NPE.NC.BRA.PT), Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL), Dorsomedial Prefrontal Cortex (NDM.NC.AL.DMPFC), Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC)), S1=Primary Somatosensory Cortex,NCP.NC.PG.S1, S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2, SC=Posterior/Dorsal Horn,BMA.SC.PH, Thalamus=Sensory Thalamus,FD.TH.SR
- Pain matrix - see Reference
map: INS=Posterior Insular Cortex,NCP.NC.INS.PIC, S1=Primary Somatosensory Cortex,NCP.NC.PG.S1, TH.VPI=Ventral Posteroinferior Nucleus,NCP.FD.TH.VPI, TH.VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL, TH.VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
References
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