BrainRegionNDM NC AL FPC

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Lateral Frontopolar Cortex

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This page covers biological details of component Lateral Frontopolar Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Orbitofrontal Cortex (NC.AL.OPFC) -> Lateral Frontopolar Cortex (NDM.NC.AL.FPC) (see Mind Maps)
  • Type: cortex
  • Brain area: Neocortical Brain - Decision Making Area
  • Brodmann ID: 10
  • Role: processor
  • Function: Emotion Regulation
  • Notes to function: Frontopolar area, contains ILC - infralimbic cortex

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Components

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Connectivity

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NDM.NC.AL.FPC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
LMC LMC.FT.NBM Basal Nucleus of Meynert modulatory-ach Physiology and pathophysiology of lower urinary tract (NBM -> MPFC, abstract)
LMC.MM.VTA Ventral Tegmental Area modulatory-da Amygdala and its network (VTA -> MPFC, abstract)
NCP NCP.NC.INS.PPC Peripaleocortical Claustral feedforward-glu Amygdalar disruption of prefrontal cortex (INS -> MPFC, abstract)
NDM NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus excitatory-glu Amygdala and its network (MD -> MPFC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FT.AM.BM Magnocellular Basal Amygdaloid Nucleus excitatory-glu (unknown reference)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu Amygdala and its network (MPFC -> BLN, abstract)
FAM.FT.SEP.SH Septohippocampal Nucleus excitatory-glu (unknown reference)
FEC FEC.FT.ACC.CORE Nucleus Accumbens Core excitatory-glu Affective basal ganglia circuit (OMPFC -> NACC, abstract)
FEC.FT.SNR.MED Substantia Nigra Pars Reticulata Medial excitatory-glu Global visual system (FrontalCortex -> BGA, abstract)
LAC LAC.FD.HT.RCH Retrochiasmatic Nucleus excitatory-glu Prefrontal Cortex (PFC) in emotional behavior (OPFC -> HT, abstract)
NDM NDM.NC.AL.DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex feedforward-glu Prefrontal Cortex (PFC) in emotional behavior (OPFC -> LPFC, abstract)
NDM.NC.AL.VACG Ventral Anterior Cingulate Area feedforward-glu Role for serotonin in moral behavior (OMPFC -> ACG, abstract)

Thirdparty Circuits

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References

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