BrainRegionNDM NC AL VMPFC

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Ventromedial Prefrontal Cortex

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This page covers biological details of component Ventromedial Prefrontal Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Orbitomedial Prefrontal Cortex (NC.AL.OMPFC) -> Medial Prefrontal Cortex (NC.AL.MPFC) -> Ventromedial Prefrontal Cortex (NDM.NC.AL.VMPFC) (see Mind Maps)
  • Type: cortex
  • Brain area: Neocortical Brain - Decision Making Area
  • Brodmann ID: 11
  • Role: cortex.generic
  • Function: Ongoing Introverted Attention with Regard to Emotions and Feelings, Reward or Punishment
  • Notes to function: lower MPFC, primary connections to limbic and sensory cortices; Reward mediated behaviours

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Components

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  • no child items defined

Connectivity

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NDM.NC.AL.VMPFC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FT.SEP.DBB Diagonal Band of Broca inhibitory-gaba (unknown reference)
FMM FMM.FT.HC.CA1D Distal CA1 of Hippocampus excitatory-glu Gating of medial prefrontal activity by the entorhinal cortex (HC -> MPFC, abstract)
NDM NDM.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu Saccadic Vision (Thalamus -> FrontalCortex, abstract)
NDM.NC.AL.DLPFCR Rostral Mid-Dorsolateral Prefrontal Cortex feedforward-glu Fear regulation (dlPFC -> vmPFC, abstract)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FT.AM.ITC Intercalated Amygdaloid Nuclei excitatory-glu (unknown reference)
FAM.FT.AM.LADL Dorsolateral Amygdaloid Nucleus excitatory-glu (unknown reference)

Thirdparty Circuits

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map: B=Basal Amygdaloid Nucleus,FAM.FT.AM.B (Parvicellular Basal Amygdaloid Nucleus (FAM.FT.AM.BP), Magnocellular Basal Amygdaloid Nucleus (FAM.FT.AM.BM)), CE=Central Amygdala,FAM.FT.AM.CEA (Central Amygdaloid Nucleus, capsular subdivision (FAM.FT.AM.CEC), Central Amygdaloid Nucleus, lateral subdivision (FAM.FT.AM.CEL), Medial Central Amygdaloid Nucleus (FAM.FT.AM.CEM)), Hippocampus=Hippocampus,FMM.FT.HC (Dentate Gyrus (FMM.FT.HC.DG), Proximal CA1 of Hippocampus (FMM.FT.HC.CA1P), Middle CA1 of Hippocampus (FMM.FT.HC.CA1M), Distal CA1 of Hippocampus (FMM.FT.HC.CA1D), Dorsolateral Cornu Ammonis of Hippocampus (FMM.FT.HC.CA2), Proximal CA3 of Hippocampus (FMM.FT.HC.CA3P), Middle CA3 of Hippocampus (FMM.FT.HC.CA3M), Distal CA3 of Hippocampus (FMM.FT.HC.CA3D)), Hypothalamus=Hypothalamus,FD.HT, ITC=Intercalated Amygdaloid Nuclei,FAM.FT.AM.ITC, LA=Lateral Amygdaloid Nucleus,FAM.FT.AM.LA (Dorsolateral Amygdaloid Nucleus (FAM.FT.AM.LADL), Ventrolateral Amygdaloid Nucleus (FAM.FT.AM.LAVL), Ventromedial Amygdaloid Nucleus (FAM.FT.AM.LAVM)), Striatum=Striatum,FEC.FT.ST (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH), Ventral Putamen (FEC.FT.PU.VT), Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), dlPFC=Mid-Dorsolateral Prefrontal Cortex,NDM.NC.AL.DLPFC (Rostral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCR), Lateral Mid-Dorsolateral Prefrontal Cortex (NDM.NC.AL.DLPFCL)), vmPFC=Ventromedial Prefrontal Cortex,NDM.NC.AL.VMPFC unavailable


References

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