Difference between revisions of "BrainCenterFAM FD HB"

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<pre style="color: green">Habenula</pre>
 
<pre style="color: green">Habenula</pre>
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainCenterFAM_FD_HB]]
 
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainCenterFAM_FD_HB]]
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'''Component items''':
 
'''Component items''':
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* '''Lateral Habenula''' (LAC.FD.LHB): Encoding negative feedback, direct; motivational control of behavior; pain processing, reward, motivation, and learning
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* '''Lateral Habenula''' (FAM.FD.LHB): Encoding negative feedback, direct; motivational control of behavior; pain processing, reward, motivation, and learning
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** [[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part]]: Encoding negative feedback, direct, Septal
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** [[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part]] (FAM.FD.LHB.MED): Encoding negative feedback, direct, Septal
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** [[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part]]: Encoding negative feedback, direct, Pallidal
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** [[BrainRegionFAM_FD_LHB_LT|Lateral Habenula Lateral Part]] (FAM.FD.LHB.LT): Encoding negative feedback, direct, Pallidal
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* [[BrainRegionFAM_FD_MHB|Medial Habenula]]: Encoding negative feedback, indirect
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* [[BrainRegionFAM_FD_MHB|Medial Habenula]] (FAM.FD.MHB): Encoding negative feedback, indirect
  
 
= Connectivity =
 
= Connectivity =
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'''Internal Regions Connections:'''
 
'''Internal Regions Connections:'''
  
 +
<img src="http://ahuman.org/svn/ahwiki/images/dot/CENTER.FAM.FD.HB_internals.dot.png" alt="unavailable" style="max-width: 100%;">
  
  
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| '''Source Region''' || '''Target Region''' || '''Reference'''
 
| '''Source Region''' || '''Target Region''' || '''Reference'''
 
|-
 
|-
−
| [[BrainRegionFAM_FD_MHB|Medial Habenula]] || [[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part]] || (unknown reference)
+
| [[BrainRegionFAM_FD_MHB|Medial Habenula]] (FAM.FD.MHB) || [[BrainRegionFAM_FD_LHB_MED|Lateral Habenula Medial Part]] (FAM.FD.LHB.MED) || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (M -> L, abstract)]
 
|}
 
|}
 +
 +
'''External Connections:'''
 +
 +
<img src="http://ahuman.org/svn/ahwiki/images/dot/CENTER.FAM.FD.HB_externals.dot.png" alt="unavailable" style="max-width: 100%;">
  
 
'''External Inbound Center Connections:'''
 
'''External Inbound Center Connections:'''
  
 
{| class=wikitable width=80%
 
{| class=wikitable width=80%
−
| '''Source Center''' || '''Reference'''
+
| '''Source Center''' || '''Sample Link''' || '''Reference'''
 
|-
 
|-
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| [[BrainCenterBGA_FT_BG|Basal Ganglia]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (GPi -> LHb, abstract)]
+
| [[BrainCenterFAM_FT_CEAM|Central Extended Amygdala]] (FAM.FT.CEAM) || [[BrainRegionFAM_FT_EPF|FAM.FT.EPF]] -> [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]]||[http://journal.frontiersin.org/article/10.3389/fnhum.2013.00826/full Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL)]
 
|-
 
|-
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| [[BrainCenterFAM_FT_EXTAM|Extended Amygdala]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (S -> MHb, abstract)]
+
| [[BrainCenterFAM_FT_SEP|Septal Nuclei]] (FAM.FT.SEP) || [[BrainRegionFAM_FT_SEP_LT|FAM.FT.SEP.LT]] -> [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)]
 
|-
 
|-
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| [[BrainCenterHP_RF|Pontine Reticular Formation]] || (unknown reference)
+
| [[BrainCenterFD_HT|Hypothalamus]] (FD.HT) || [[BrainRegionLAC_FD_HT_VLPO|LAC.FD.HT.VLPO]] -> [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]]||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
 
|-
 
|-
−
| [[BrainCenterHP_TG|Pontine Tegmental Nuclei]] || (unknown reference)
+
| [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) || [[BrainRegionFEC_FT_GPI_DS|FEC.FT.GPI.DS]] -> [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]]||[http://www.scholarpedia.org/article/Habenula Habenula Connections (GPi -> LHb, abstract)]
 
|-
 
|-
−
| [[BrainCenterHTA_FD_HT|Hypothalamus]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LPO -> LHb, abstract)]
+
| [[BrainRegionLMC_HT_LC|Locus Coeruleus]] (LMC.HT.LC) || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] -> [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]]||[http://www.nature.com/nrn/journal/v11/n6/fig_tab/nrn2849_F7.html Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)]
−
|-
+
−
| [[BrainCenterMM_RF|Mesencephalic Reticular Formation]] || (unknown reference)
+
 
|}
 
|}
  
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{| class=wikitable width=80%
 
{| class=wikitable width=80%
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| '''Target Center''' || '''Reference'''
+
| '''Target Center''' || '''Sample Link''' || '''Reference'''
 +
|-
 +
| [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] -> [[BrainRegionFEC_FT_SNC_LT|FEC.FT.SNC.LT]]||[http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)]
 +
|-
 +
| [[BrainCenterHL_RF|Medullary Reticular Formation]] (HL.RF) || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] -> [[BrainRegionLMC_HL_RP_MG|LMC.HL.RP.MG]]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> MRN, abstract)]
 
|-
 
|-
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| [[BrainCenterBGA_FT_BG|Basal Ganglia]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> SNc, abstract)]
+
| [[BrainCenterHT_TG|Pontine Tegmental Nuclei]] (HT.TG) || [[BrainRegionFAM_FD_LHB_LT|FAM.FD.LHB.LT]] -> [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbL -> RMTg)]
 
|-
 
|-
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| [[BrainCenterHP_TG|Pontine Tegmental Nuclei]] || [http://www.surgicalneurologyint.com/article.asp?issn=2152-7806;year=2012;volume=3;issue=2;spage=40;epage=46;aulast=Langevin Amygdala and its network (LHB -> RMTG, abstract)]
+
| [[BrainRegionLMC_MM_VTA|Ventral Tegmental Area]] (LMC.MM.VTA) || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] -> [[BrainRegionLMC_MM_VTA|LMC.MM.VTA]]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)]
 
|-
 
|-
−
| [[BrainCenterMM_RF|Mesencephalic Reticular Formation]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (LHb -> MR, abstract)]
+
| [[BrainCenterMM_RF|Mesencephalic Reticular Formation]] (MM.RF) || [[BrainRegionFAM_FD_LHB_MED|FAM.FD.LHB.MED]] -> [[BrainRegionLMC_MM_RP_DRN|LMC.MM.RP.DRN]]||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)]
 
|-
 
|-
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| [[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands]] || [http://www.scholarpedia.org/article/Habenula Habenula Connections (MHb -> PB)]
+
| [[BrainRegionTARGET_TEA_ENDOCRINE|Endocrine Glands]] (TARGET.TEA.ENDOCRINE) || [[BrainRegionFAM_FD_MHB|FAM.FD.MHB]] -> [[BrainRegionTARGET_TEA_ENDOCRINE|TARGET.TEA.ENDOCRINE]]||[http://www.scholarpedia.org/article/Habenula Habenula Connections (MHb -> PB)]
 
|}
 
|}

Latest revision as of 18:52, 28 November 2018

Habenula

@@Home -> BiologicalLifeResearch -> BrainCenterFAM_FD_HB

This page covers biological details of component group Habenula. Component group is part of aHuman target integrated biological model.

  • Top-down path to center: Forebrain Diencephalon -> Habenula (FAM.FD.HB) (see Mind Maps)
  • Function: Encoding negative feedback

(generated)

Components

(generated)


Component items:

  • Lateral Habenula (FAM.FD.LHB): Encoding negative feedback, direct; motivational control of behavior; pain processing, reward, motivation, and learning
  • Medial Habenula (FAM.FD.MHB): Encoding negative feedback, indirect

Connectivity

(generated)


Internal Regions Connections:

unavailable


Source Region Target Region Reference
Medial Habenula (FAM.FD.MHB) Lateral Habenula Medial Part (FAM.FD.LHB.MED) Connectivity map of the habenula (M -> L, abstract)

External Connections:

unavailable

External Inbound Center Connections:

Source Center Sample Link Reference
Central Extended Amygdala (FAM.FT.CEAM) FAM.FT.EPF -> FAM.FD.LHB.LT Regulation of the rapid eye movement (REM) sleep by habenular projection (EPN -> LHbL)
Septal Nuclei (FAM.FT.SEP) FAM.FT.SEP.LT -> FAM.FD.LHB.MED Both LHb and MHb control the dopaminergic and serotonergic systems (LS -> LHbM)
Hypothalamus (FD.HT) LAC.FD.HT.VLPO -> FAM.FD.LHB.LT Habenula Connections (LPO -> LHb, abstract)
Basal Ganglia (FEC.FT.BG) FEC.FT.GPI.DS -> FAM.FD.LHB.LT Habenula Connections (GPi -> LHb, abstract)
Locus Coeruleus (LMC.HT.LC) LMC.HT.LC -> FAM.FD.LHB.LT Contribution of nAChR subunits to nicotine withdrawal symptoms (LC -> LHB, abstract)

External Outbound Center Connections:

Target Center Sample Link Reference
Basal Ganglia (FEC.FT.BG) FAM.FD.LHB.MED -> FEC.FT.SNC.LT Habenula Connections (LHb -> SNc, abstract)
Medullary Reticular Formation (HL.RF) FAM.FD.LHB.MED -> LMC.HL.RP.MG Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> MRN, abstract)
Pontine Tegmental Nuclei (HT.TG) FAM.FD.LHB.LT -> FEC.HT.TG.RMTG Both LHb and MHb control the dopaminergic and serotonergic systems (LHbL -> RMTg)
Ventral Tegmental Area (LMC.MM.VTA) FAM.FD.LHB.MED -> LMC.MM.VTA Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> VTA)
Mesencephalic Reticular Formation (MM.RF) FAM.FD.LHB.MED -> LMC.MM.RP.DRN Both LHb and MHb control the dopaminergic and serotonergic systems (LHbM -> DRN)
Endocrine Glands (TARGET.TEA.ENDOCRINE) FAM.FD.MHB -> TARGET.TEA.ENDOCRINE Habenula Connections (MHb -> PB)
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