Difference between revisions of "BrainRegionLPC HT PRF PB"
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* '''Type''': nucleus | * '''Type''': nucleus | ||
* '''Quality''': L0 | * '''Quality''': L0 | ||
| − | * '''Brain area''': [[BrainAreaLPC|Lower Brain - Peripheral Control Area]] | + | * '''Brain area''': [[BrainAreaLPC|Lower Brain - Peripheral Control Area]] (LPC) |
| + | * '''Area circuit''': Pain Sensations (SP) | ||
* '''Role''': processor.affective | * '''Role''': processor.affective | ||
* '''Function''': Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception | * '''Function''': Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception | ||
| Line 34: | Line 35: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_IPAC_MED|FAM.FT.IPAC.MED]] || Medial Interstitial Anterior Commissural Nucleus || excitatory-glu || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_IPAC_MED|FAM.FT.IPAC.MED]] || Medial Interstitial Anterior Commissural Nucleus || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
| − | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (SOL -> PB)] | + | | [[BrainAreaLPC|LPC]] || [[BrainRegionLPC_HL_SOL|LPC.HL.SOL]] || Solitary Nucleus || excitatory-glu || uncertain ||[http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (SOL -> PB)] |
|- | |- | ||
| − | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG|NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || [http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] | + | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_NC_AL_SGCG|NCP.NC.AL.SGCG]] || Subgenual Cingulate Cortex || excitatory-glu || uncertain ||[http://openagrosrl.com/www/page/292/ Motor neurons control (CTX -> PRF, abstract)] |
|} | |} | ||
| Line 46: | Line 47: | ||
{| class=wikitable width=80% | {| class=wikitable width=80% | ||
| − | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
| − | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEL|FAM.FT.AM.CEL]] || Central Amygdaloid Nucleus, lateral subdivision || excitatory-glu || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (PB -> AM, abstract)] | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEL|FAM.FT.AM.CEL]] || Central Amygdaloid Nucleus, lateral subdivision || excitatory-glu || uncertain || [http://neuropolitics.org/defaultmay10.asp Amygdalar disruption of prefrontal cortex (PB -> AM, abstract)] |
|- | |- | ||
| − | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)] | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> NAc, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)] | + | | || [[BrainRegionFEC_FT_PU_LT|FEC.FT.PU.LT]] || Dorsal Putamen Lateral || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)] |
|- | |- | ||
| − | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || excitatory-glu || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)] | + | | || [[BrainRegionFEC_FT_PU_MED|FEC.FT.PU.MED]] || Dorsal Putamen Medial || excitatory-glu || uncertain || [http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html Bowels control brain: gut hormones and obesity (PBN -> DS, abstract)] |
|- | |- | ||
| − | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || [http://www.pnas.org/content/103/32/12150/F7.expansion.html Food-entrainable circadian oscillator (PBN -> DMH)] | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_DM|LAC.FD.HT.DM]] || Dorsomedial Hypothalamic Nucleus || excitatory-glu || uncertain || [http://www.pnas.org/content/103/32/12150/F7.expansion.html Food-entrainable circadian oscillator (PBN -> DMH)] |
|- | |- | ||
| − | | || [[BrainRegionLAC_HL_VGN|LAC.HL.VGN]] || Vagus Nucleus || excitatory-glu || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (PBN -> DVM)] | + | | || [[BrainRegionLAC_HL_VGN|LAC.HL.VGN]] || Vagus Nucleus || excitatory-glu || uncertain || [http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders Physiology and pathophysiology of lower urinary tract (PBN -> DVM)] |
|- | |- | ||
| − | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_FD_TH_VPI|NCP.FD.TH.VPI]] || Ventral Posteroinferior Nucleus || excitatory-glu || (unknown reference) | + | | [[BrainAreaNCP|NCP]] || [[BrainRegionNCP_FD_TH_VPI|NCP.FD.TH.VPI]] || Ventral Posteroinferior Nucleus || excitatory-glu || uncertain || (unknown reference) |
|- | |- | ||
| − | | || [[BrainRegionNCP_FD_TH_VPM|NCP.FD.TH.VPM]] || Ventral Posteromedial Nucleus || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (PB -> VPMpc)] | + | | || [[BrainRegionNCP_FD_TH_VPM|NCP.FD.TH.VPM]] || Ventral Posteromedial Nucleus || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (PB -> VPMpc)] |
|- | |- | ||
| − | | || [[BrainRegionNCP_NC_INS_PIC|NCP.NC.INS.PIC]] || Posterior Insular Cortex || excitatory-glu || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (PB -> Gud, abstract)] | + | | || [[BrainRegionNCP_NC_INS_PIC|NCP.NC.INS.PIC]] || Posterior Insular Cortex || excitatory-glu || uncertain || [http://www.sciencedirect.com/science/article/pii/S0149763401000215 Gustatory sensory system of rat and macaque (PB -> Gud, abstract)] |
|} | |} | ||
Latest revision as of 18:30, 28 April 2019
Parabrachial Nucleus
@@Home -> BiologicalLifeResearch -> BrainAreaLPC -> BrainRegionLPC_HT_PRF_PB
This page covers biological details of component Parabrachial Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Hindbrain Metencephalon -> Pontine Reticular Formation (HT.RF) -> Pontine Reticular Formation, Lateral Column (HT.RF.LAT) -> Parabrachial Nucleus (LPC.HT.PRF.PB) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Lower Brain - Peripheral Control Area (LPC)
- Area circuit: Pain Sensations (SP)
- Role: processor.affective
- Function: Source of short-latency nociceptive input; sense of physiological condition of body well-being or interoception
- Notes to function:
- major relay site for visceral afferents ascending through ventrobasal thalamus and terminating in insular cortex
(generated)
Components
(generated)
Component items:
- Subbrachial Nucleus
- Lateral Parabrachial Nucleus
- External Lateral Parabrachial Nucleus
- Medial Parabrachial Nucleus
Connectivity
(generated)
Inbound Region Connections:
| Source Area | Source Region | Source Name | Type | Role | Reference |
| FAM | FAM.FT.IPAC.MED | Medial Interstitial Anterior Commissural Nucleus | excitatory-glu | uncertain | (unknown reference) |
| LPC | LPC.HL.SOL | Solitary Nucleus | excitatory-glu | uncertain | Amygdalar disruption of prefrontal cortex (SOL -> PB) |
| NCP | NCP.NC.AL.SGCG | Subgenual Cingulate Cortex | excitatory-glu | uncertain | Motor neurons control (CTX -> PRF, abstract) |
Outbound Region Connections:
Thirdparty Circuits
(generated)
- Gustatory sensory system of rat and macaque - see Reference (CP.GUSTATORY-OLFACTORY)
EnP=Endopiriform Nucleus,FAM.FT.EPF Gud=Insular Cortex,NC.INS Gug=Insular Cortex,NC.INS HF=Hippocampal Formation,FMM.FT.HF IadIap=Insular Cortex,NC.INS Iav=Insular Cortex,NC.INS NST=Solitary Nucleus,LPC.HL.SOL PB=Parabrachial Nucleus,LPC.HT.PRF.PB PiR=Piriform Cortex,NSA.NC.PH.PIR PrC=Perirhinal Cortex,FMM.NC.PH.PER VPMpc=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
- Food-entrainable circadian oscillator - see Reference (CP.FOOD-OCSILLATOR)
DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN NTS=Solitary Nucleus,LPC.HL.SOL PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVH=Paraventricular Nucleus,LAC.FD.HT.PV SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN
- Bowels control brain: gut hormones and obesity - see Reference (CP.BOWELS)
AMY=Amygdala,FAM.FT.AM ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR DS=Dorsal Striatum,FEC.FT.DST (see Basal Ganglia) LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN ME=Endocrine Glands,TARGET.TEA.ENDOCRINE NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) NTS=Solitary Nucleus,LPC.HL.SOL OFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PVN=Paraventricular Nucleus,LAC.FD.HT.PV VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM VTA=Ventral Tegmental Area,LMC.MM.VTA
- Physiology and pathophysiology of lower urinary tract - see Reference (CM.ONUF)
CN=Caudate Nucleus,FEC.FT.CN (see Basal Ganglia) DVM=Vagus Nucleus,LAC.HL.VGN IMG=Inferior Mesenteric Ganglion,LAC.PN.SYM.IMG IML=Intermediolateral Nucleus,LAC.SC.IZ.IML LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO NBM=Basal Nucleus of Meynert,LMC.FT.NBM ONF=Onuf's Nucleus,LPC.SC.VH.ONF PBN=Parabrachial Nucleus,LPC.HT.PRF.PB PEL=Pelvic Peripheral Ganglion,LAC.PN.PSYM.PPG PU=Dorsal Putamen Lateral,FEC.FT.PU.LT PVN=Paraventricular Nucleus,LAC.FD.HT.PV SNC=Substantia Nigra Pars Compacta Lateral,FEC.FT.SNC.LT SPS=Sacral Parasympathetic Nucleus,LAC.SC.IZ.SPS VTA=Ventral Tegmental Area,LMC.MM.VTA ZI=Subthalamic Nucleus Caudal,BGA.FD.STN.ZI
- Amygdalar disruption of prefrontal cortex - see Reference (CF.AM-DISRUPTION)
ACG=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AM=Amygdala,FAM.FT.AM HC=Hippocampus,FMM.FT.HC (see Hippocampal Formation) HT.L=Lateral Hypothalamic Area,LAC.FD.HT.LT (see Hypothalamus) HT.PV=Paraventricular Nucleus,LAC.FD.HT.PV INS=Insular Cortex,NC.INS LC=Locus Coeruleus,LMC.HT.LC MPFC=Orbitofrontal Cortex,NC.AL.OPFC (see Orbitomedial Prefrontal Cortex) PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PUT=Endocrine Glands,TARGET.TEA.ENDOCRINE SOL=Solitary Nucleus,LPC.HL.SOL TH=Thalamus,FD.TH
- Afferent pain pathways - see Reference (CF.PAIN-PATH)
ACC=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area) AMY=Amygdala,FAM.FT.AM BG=Basal Ganglia,FEC.FT.BG Cerebellum=Cerebellar Complex,LLC.HT.CRC Insula=Insular Cortex,NC.INS PAG=Periaqueductal Gray Matter,LMC.MM.PAG PB=Parabrachial Nucleus,LPC.HT.PRF.PB PFC=Prefrontal Cortex,NC.AL.PFC S1=Primary Somatosensory Cortex,NCP.NC.PG.S1 S2=Secondary Somatosensory Cortex,NCP.NC.PG.S2 SC=Posterior/Dorsal Horn,BMA.SC.PH Thalamus=Sensory Thalamus,FD.TH.SR
References
(generated)
- http://www.sciencedirect.com/science/article/pii/S0149763401000215
- http://www.pnas.org/content/103/32/12150/F7.expansion.html
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://www.intechopen.com/books/computational-intelligence-in-electromyography-analysis-a-perspective-on-current-applications-and-future-challenges/sphincter-emg-for-diagnosing-multiple-system-atrophy-and-related-disorders
- http://neuropolitics.org/defaultmay10.asp
- http://www.nature.com/nrn/journal/v14/n7/fig_tab/nrn3516_F2.html
