Difference between revisions of "BrainRegionFEC FT SNC MED"
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<pre style="color: green">Substantia Nigra Pars Compacta Medial</pre> | <pre style="color: green">Substantia Nigra Pars Compacta Medial</pre> | ||
@@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_SNC_MED]] | @@[[Home]] -> [[BiologicalLifeResearch]] -> [[BrainAreaFEC]] -> [[BrainRegionFEC_FT_SNC_MED]] | ||
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Region is part of aHuman target integrated biological model. | Region is part of aHuman target integrated biological model. | ||
− | * '''Top-down path to region''': Forebrain Telencephalon -> Basal Ganglia ( | + | * '''Top-down path to region''': Forebrain Telencephalon -> [[BrainCenterFEC_FT_BG|Basal Ganglia]] (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> [[BrainRegionFEC_FT_SNC_MED|Substantia Nigra Pars Compacta Medial]] (FEC.FT.SNC.MED) (see [[OverallMindMaps|Mind Maps]]) |
* '''Type''': nucleus | * '''Type''': nucleus | ||
− | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] | + | * '''Quality''': L0 |
− | * '''Role''': | + | * '''Brain area''': [[BrainAreaFEC|Forebrain - Execution Control Area]] (FEC) |
+ | * '''Area circuit''': Motor Motivational Salience (FECLM) | ||
+ | * '''Role''': basal.ganglia.nigracompacta | ||
* '''Function''': motivational loop | * '''Function''': motivational loop | ||
+ | * '''Notes to function''': | ||
+ | ** VP, ventral circuits | ||
(generated) | (generated) | ||
= Components = | = Components = | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Reference''' | + | | '''Source Area''' || '''Source Region''' || '''Source Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_BNST|FAM.FT.BNST]] || Bed Nucleus of Stria Terminalis || excitatory-glu || uncertain ||(unknown reference) |
|- | |- | ||
− | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || inhibitory-gaba || (unknown reference) | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_CORE|FEC.FT.ACC.CORE]] || Nucleus Accumbens Core || inhibitory-gaba || uncertain ||(unknown reference) |
|- | |- | ||
− | | || [[BrainRegionFEC_FT_GPI_RM|FEC.FT.GPI.RM]] || Globus Pallidus Internal Rostromedial || inhibitory-gaba || [https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] | + | | || [[BrainRegionFEC_FT_GPI_RM|FEC.FT.GPI.RM]] || Globus Pallidus Internal Rostromedial || inhibitory-gaba || uncertain ||[https://www.google.ru/search?hl=rutbo=ptbm=bksq=isbn:0080887988 Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract)] |
|- | |- | ||
− | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || (unknown reference) | + | | || [[BrainRegionFEC_FT_SNR_MED|FEC.FT.SNR.MED]] || Substantia Nigra Pars Reticulata Medial || inhibitory-gaba || uncertain ||(unknown reference) |
|- | |- | ||
− | | [[BrainAreaLMC|LMC]] || [[ | + | | || [[BrainRegionFEC_HT_TG_RMTG|FEC.HT.TG.RMTG]] || Rostromedial Tegmental Nucleus || inhibitory-gaba || uncertain ||[http://www.nature.com/neuro/journal/v17/n9/fig_tab/nn.3779_F2.html Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract)] |
+ | |- | ||
+ | | [[BrainAreaLMC|LMC]] || [[BrainRegionLMC_HT_LC|LMC.HT.LC]] || Locus Coeruleus || modulatory-ne || uncertain ||(unknown reference) | ||
|} | |} | ||
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{| class=wikitable width=80% | {| class=wikitable width=80% | ||
− | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Reference''' | + | | '''Target Area''' || '''Target Region''' || '''Target Name''' || '''Type''' || '''Role''' || '''Reference''' |
|- | |- | ||
− | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || modulatory-da || (unknown reference) | + | | [[BrainAreaFAM|FAM]] || [[BrainRegionFAM_FT_AM_CEM|FAM.FT.AM.CEM]] || Medial Central Amygdaloid Nucleus || modulatory-da || uncertain || (unknown reference) |
|- | |- | ||
− | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || ( | + | | [[BrainAreaFEC|FEC]] || [[BrainRegionFEC_FT_ACC_SH|FEC.FT.ACC.SH]] || Nucleus Accumbens Shell || modulatory-da || uncertain || [http://jn.physiology.org/content/107/10/2633 Connectivity map of the habenula (SNc -> CPu, abstract)] |
|- | |- | ||
− | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || modulatory-da || (unknown reference) | + | | [[BrainAreaLAC|LAC]] || [[BrainRegionLAC_FD_HT_SUM|LAC.FD.HT.SUM]] || Supramammillary Nucleus || modulatory-da || uncertain || (unknown reference) |
|- | |- | ||
− | | [[BrainAreaLRC|LRC]] || [[ | + | | [[BrainAreaLRC|LRC]] || [[BrainRegionLRC_HT_PRF_PVR|LRC.HT.PRF.PVR]] || Parvocellular Reticular Nucleus || modulatory-da || uncertain || (unknown reference) |
|} | |} | ||
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(generated) | (generated) | ||
− | * | + | * [http://www.endurance-education.com/home/aragorn/www/endurance/htdocs/wp-content/uploads/Stephenson-Jones-2012-Fig-9-1024x489.png Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey] - see [http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs Reference] (CM.SN-PPN) |
+ | |||
+ | GPe=Globus Pallidus External,FEC.FT.GPE (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | GPi=Globus Pallidus Internal,FEC.FT.GPI (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PPN=[[BrainRegionLMC_HT_TG_PPN|Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN]] | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | STN=Subthalamic Nucleus,FEC.FD.STN (see [[BrainCenterFEC_FD_STA|Subthalamus Area]]) | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/ae877872fea7af03677243fd8481c11d.png" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
+ | * [http://d2avczb82rh8fa.cloudfront.net/content/jn/107/10/2633/F1.large.jpg Connectivity map of the habenula] - see [http://jn.physiology.org/content/107/10/2633 Reference] (CF.HB-CONN) | ||
+ | |||
+ | CPu=Striatum,FEC.FT.ST (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | EP=[[BrainRegionFAM_FT_EPF|Endopiriform Nucleus,FAM.FT.EPF]] | ||
+ | Hippo=Hippocampus,FMM.FT.HC (see [[BrainCenterFMM_FT_HF|Hippocampal Formation]]) | ||
+ | IPN=[[BrainRegionFEC_HT_TG_IPD|Interpeduncular Nucleus,FEC.HT.TG.IPD]] | ||
+ | L=Lateral Habenula,FAM.FD.LHB (see [[BrainCenterFAM_FD_HB|Habenula]]) | ||
+ | LH=[[BrainRegionLAC_FD_HT_LTN|Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN]] | ||
+ | M=[[BrainRegionFAM_FD_MHB|Medial Habenula,FAM.FD.MHB]] | ||
+ | NAc=Accumbens Nucleus,FEC.FT.ACC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | PAG=[[BrainRegionLMC_MM_PAG|Periaqueductal Gray Matter,LMC.MM.PAG]] | ||
+ | Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see [[BrainCenterHL_RF|Medullary Reticular Formation]]) | ||
+ | SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see [[BrainCenterFEC_FT_BG|Basal Ganglia]]) | ||
+ | Septum=[[BrainCenterFAM_FT_SEP|Septal Nuclei,FAM.FT.SEP]] | ||
+ | VTA=[[BrainRegionLMC_MM_VTA|Ventral Tegmental Area,LMC.MM.VTA]] | ||
+ | <img src="http://ahuman.org/svn/ahwiki/images/ext/213e030f063f9640f8ace79244e622d1.jpg" alt=alt="unavailable" style="max-width: 100%;"> | ||
+ | |||
= References = | = References = | ||
(generated) | (generated) | ||
− | * | + | * http://www.endurance-education.com/endurance-education-com/does-only-our-brainstem-select-our-motor-programs |
+ | * http://jn.physiology.org/content/107/10/2633 |
Latest revision as of 18:26, 28 April 2019
Substantia Nigra Pars Compacta Medial
@@Home -> BiologicalLifeResearch -> BrainAreaFEC -> BrainRegionFEC_FT_SNC_MED
This page covers biological details of component Substantia Nigra Pars Compacta Medial. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Substantia Nigra (FEC.FT.SN) -> Substantia Nigra Pars Compacta (FEC.FT.SNC) -> Substantia Nigra Pars Compacta Medial (FEC.FT.SNC.MED) (see Mind Maps)
- Type: nucleus
- Quality: L0
- Brain area: Forebrain - Execution Control Area (FEC)
- Area circuit: Motor Motivational Salience (FECLM)
- Role: basal.ganglia.nigracompacta
- Function: motivational loop
- Notes to function:
- VP, ventral circuits
(generated)
Components
(generated)
- no child items defined
Connectivity
(generated)
Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Role | Reference |
FAM | FAM.FT.BNST | Bed Nucleus of Stria Terminalis | excitatory-glu | uncertain | (unknown reference) |
FEC | FEC.FT.ACC.CORE | Nucleus Accumbens Core | inhibitory-gaba | uncertain | (unknown reference) |
FEC.FT.GPI.RM | Globus Pallidus Internal Rostromedial | inhibitory-gaba | uncertain | Prefrontal Cortex (PFC) in motor behavior (GP -> SN, abstract) | |
FEC.FT.SNR.MED | Substantia Nigra Pars Reticulata Medial | inhibitory-gaba | uncertain | (unknown reference) | |
FEC.HT.TG.RMTG | Rostromedial Tegmental Nucleus | inhibitory-gaba | uncertain | Both LHb and MHb control the dopaminergic and serotonergic systems (RMTg -> SNc, abstract) | |
LMC | LMC.HT.LC | Locus Coeruleus | modulatory-ne | uncertain | (unknown reference) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Role | Reference |
FAM | FAM.FT.AM.CEM | Medial Central Amygdaloid Nucleus | modulatory-da | uncertain | (unknown reference) |
FEC | FEC.FT.ACC.SH | Nucleus Accumbens Shell | modulatory-da | uncertain | Connectivity map of the habenula (SNc -> CPu, abstract) |
LAC | LAC.FD.HT.SUM | Supramammillary Nucleus | modulatory-da | uncertain | (unknown reference) |
LRC | LRC.HT.PRF.PVR | Parvocellular Reticular Nucleus | modulatory-da | uncertain | (unknown reference) |
Thirdparty Circuits
(generated)
- Summary of the organization of the substantia nigra pars reticulata and pedunculopontine nucleus in lamprey - see Reference (CM.SN-PPN)
GPe=Globus Pallidus External,FEC.FT.GPE (see Basal Ganglia) GPi=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia) PPN=Pedunculopontine Tegmental Nuclei,LMC.HT.TG.PPN SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) SNr=Substantia Nigra Pars Reticulata,FEC.FT.SNR (see Basal Ganglia) STN=Subthalamic Nucleus,FEC.FD.STN (see Subthalamus Area)
- Connectivity map of the habenula - see Reference (CF.HB-CONN)
CPu=Striatum,FEC.FT.ST (see Basal Ganglia) EP=Endopiriform Nucleus,FAM.FT.EPF Hippo=Hippocampus,FMM.FT.HC (see Hippocampal Formation) IPN=Interpeduncular Nucleus,FEC.HT.TG.IPD L=Lateral Habenula,FAM.FD.LHB (see Habenula) LH=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN M=Medial Habenula,FAM.FD.MHB NAc=Accumbens Nucleus,FEC.FT.ACC (see Basal Ganglia) PAG=Periaqueductal Gray Matter,LMC.MM.PAG Raphe=Raphe Nuclei of Medulla,LMC.HL.RP (see Medullary Reticular Formation) SNc=Substantia Nigra Pars Compacta,FEC.FT.SNC (see Basal Ganglia) Septum=Septal Nuclei,FAM.FT.SEP VTA=Ventral Tegmental Area,LMC.MM.VTA
References
(generated)