BrainRegionFEC FT GPI LT

Globus Pallidus Internal Lateral

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This page covers biological details of component Globus Pallidus Internal Lateral. Region is part of aHuman target integrated biological model.

• Top-down path to region: Forebrain Telencephalon -> Basal Ganglia (FEC.FT.BG) -> Globus Pallidus (FEC.FT.GP) -> Dorsal Pallidum (FEC.FT.DP) -> Globus Pallidus Internal (FEC.FT.GPI) -> Globus Pallidus Internal Lateral (FEC.FT.GPI.LT) (see Mind Maps)
• Type: nucleus
• Brain area: Forebrain - Execution Control Area
• Role: basal.ganglia.suppress
• Function: Motor flexor loop
• Notes to function: output nuclei of basal ganglia to neocortex, leg, arm, face; lateral - leg, medial - arm, ventral - face

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FEC	FEC.FD.STN.LT	Subthalamic Nucleus Lateral	excitatory-glu	Basal Ganglia Activity (STN -> GPi, abstract)
	FEC.FT.GPE.LT	Globus Pallidus External Lateral	inhibitory-gaba	(unknown reference)
	FEC.FT.PU.LT	Dorsal Putamen Lateral	inhibitory-gaba	Habenula Connections (CPu -> GPi, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
FEC	FEC.FD.TH.CM	Centromedian Nucleus of Thalamus	inhibitory-gaba	Thalamocortical relationships (sCM -> CM, abstract)
NMA	NMA.FD.TH.VL	Ventral Lateral Nucleus	inhibitory-gaba	Thalamocortical relationships (s2VL -> VL, abstract)

Thirdparty Circuits

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• Thalamocortical relationships - see Reference (CL.THALAMUS-PROJECTIONS)

A=Anterior Nucleus of Thalamus,FD.TH.AN (see Cognitive Thalamus)
CM=Centromedian Nucleus of Thalamus,FEC.FD.TH.CM
LD=Lateral Dorsal Nucleus of Thalamus,FMM.FD.TH.LD
LGN=Lateral Geniculate Nucleus,NSA.FD.LGN
LP=Lateral Posterior Nucleus of Thalamus,NPE.FD.TH.LP
MD=Mediodorsal Nucleus of Thalamus,FD.TH.MD (see Cognitive Thalamus)
MGN=Medial Geniculate Body,NSA.FD.TH.MGB
P=Ventral Posterior Nuclei,NSA.FD.TH.VP (see Sensory Thalamus)
VA=Ventral Anterior Nucleus,NMA.FD.TH.VA
VL=Ventral Lateral Nucleus,NMA.FD.TH.VL
VPL=Ventral Posterolateral Nucleus,NCP.FD.TH.VPL
VPM=Ventral Posteromedial Nucleus,NCP.FD.TH.VPM
pA=Posterior Cingulate Cortex,NCP.NC.MPL.PSCG
pCM=Dorsal Putamen,FEC.FT.DPU (see Basal Ganglia)
pLD=Anterior Cingulate Cortex,NC.AL.ACG (see Anterior Cingulate Area)
pLGN=Primary Visual Cortex,NSA.NC.OCC.V1
pLP=Superior Parietal Lobule,NC.SPL
pMD=Prefrontal Cortex,NC.AL.PFC
pMGN=Primary Auditory Cortex,NSA.NC.TTG.A1
pP=Insular Cortex,NC.INS
pVA=Supplementary Motor Cortex,NMA.NC.SMC
pVL=Motor Cortex,NMA.NC.MC
pVPL=Primary Somatosensory Cortex,NCP.NC.PG.S1
pVPM=Precentral Cortex,NCP.NC.PO.PCC
s1A=Subiculum,FMM.FT.HF.SUB (see Hippocampal Formation)
s1MD=Septal Nuclei,FAM.FT.SEP
s1P=Central Cervical Nucleus,LPC.SC.IZ.CCV
s1VL=Dentate Nucleus,LLC.HT.CR.DN
s2A=Mammillary Body,FD.MB (see Hypothalamus)
s2MD=Piriform Cortex,NSA.NC.PH.PIR
s2P=Principal Trigeminal Nucleus,LPC.HT.PN.PTR
s2VL=Basal Ganglia,FEC.FT.BG
s3MD=Prefrontal Cortex,NC.AL.PFC
sCM=Globus Pallidus Internal,FEC.FT.GPI (see Basal Ganglia)
sLD=Superior Parietal Lobule,NC.SPL
sLP=Superior Colliculus,MM.SC (see Reflexes Nuclei of Midbrain Mesencephalon)
sVA=Basal Ganglia,FEC.FT.BG
sVPL=Marginal Nucleus,LPC.SC.PH.MG (see Posterior/Dorsal Horn)
sVPM=Solitary Nucleus,LPC.HL.SOL

References

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• http://what-when-how.com/neuroscience/the-thalamus-and-cerebral-cortex-integrative-systems-part-2/