BrainRegionLAC FD HT VM
Ventromedial Hypothalamic Nucleus
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This page covers biological details of component Ventromedial Hypothalamic Nucleus. Region is part of aHuman target integrated biological model.
- Top-down path to region: Forebrain Diencephalon -> Hypothalamus (FD.HT) -> Anterior Hypothalamus Area (LAC.FD.HT.AHT) -> Tuberal Area (LAC.FD.HT.TUB) -> Ventromedial Hypothalamic Nucleus (LAC.FD.HT.VM) (see Mind Maps)
- Type: nucleus
- Brain area: Lower Brain - Autonomous Control Area
- Role: processor.autonomic
- Function: Satiety, control of eating
- Notes to function: medial of tuberculum
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Components
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- no child items defined
Connectivity
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Inbound Region Connections:
Source Area | Source Region | Source Name | Type | Reference |
FAM | FAM.FT.AM.MPV | Medial Posterior Ventral Amygdaloid Nucleus | inhibitory-gaba | Role for serotonin in moral behavior (AMY -> HYP, abstract) |
FMM | FMM.FT.HF.SUBP | Proximal Subiculum | excitatory-glu | (unknown reference) |
LAC | LAC.FD.HT.AH | Anterior Hypothalamic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (AH -> VMN) |
LAC.FD.HT.AR | Arcuate Nucleus of Hypothalamus | excitatory-glu | Schematic of hypothalamic circuitry underlying satiety (ARC -> VMH) | |
LAC.FD.HT.PRM | Premammillary Nucleus | excitatory-glu | (unknown reference) |
Outbound Region Connections:
Target Area | Target Region | Target Name | Type | Reference |
FAM | FAM.FT.BNST | Bed Nucleus of Stria Terminalis | excitatory-glu | (unknown reference) |
FEC | FEC.FD.STN.CD | Subthalamic Nucleus Caudal | excitatory-glu | (unknown reference) |
FEC.FT.ACC.SH | Nucleus Accumbens Shell | excitatory-glu | Bowels control brain: gut hormones and obesity (VMN -> NAc, abstract) | |
LAC | LAC.FD.HT.DM | Dorsomedial Hypothalamic Nucleus | excitatory-glu | Intrahypothalamic connections important for neural control of food intake and energy balance (VMN -> DMN) |
LAC.FD.HT.LTN | Lateral Hypothalamic Nucleus | excitatory-glu | Glucose-sensing neural network (VMH -> LHA) | |
LAC.FD.HT.PV | Paraventricular Nucleus | excitatory-glu | Glucose-sensing neural network (VMH -> PVH) | |
LAC.FD.HT.VLPO | Ventrolateral Preoptic Nucleus | excitatory-glu | (unknown reference) | |
LPC | LPC.HL.SOL | Solitary Nucleus | excitatory-glu | Bowels control brain: gut hormones and obesity (VMN -> NTS) |
Thirdparty Circuits
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map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, PVH=Paraventricular Nucleus,LAC.FD.HT.PV, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: AMY=Amygdala,FAM.FT.AM, ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DS=Dorsal Striatum,FEC.FT.DST (Caudate Nucleus Head (FEC.FT.CN.HD), Caudate Nucleus Body (FEC.FT.CN.BD), Caudate Nucleus Tail (FEC.FT.CN.TL), Dorsal Putamen Lateral (FEC.FT.PU.LT), Dorsal Putamen Medial (FEC.FT.PU.MED)), LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, ME=Endocrine Glands,TARGET.TEA.ENDOCRINE, NAc=Accumbens Nucleus,FEC.FT.ACC (Nucleus Accumbens Core (FEC.FT.ACC.CORE), Nucleus Accumbens Shell (FEC.FT.ACC.SH)), NTS=Solitary Nucleus,LPC.HL.SOL, OFC=Orbitofrontal Cortex,NC.AL.OPFC (Lateral Frontopolar Cortex (NDM.NC.AL.FPC), Most Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCR), Sulcal Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCS), Medial Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCM), Lateral Rostral Orbitofrontal Cortex (NDM.NC.AL.ROFCL)), PBN=Parabrachial Nucleus,LPC.HT.PRF.PB, PVN=Paraventricular Nucleus,LAC.FD.HT.PV, VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM, VTA=Ventral Tegmental Area,LMC.MM.VTA
- Intrahypothalamic connections important for neural control of food intake and energy balance - see Reference
map: AH=Anterior Hypothalamic Nucleus,LAC.FD.HT.AH, ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMN=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, MPOA=Median Preoptic Nucleus,LAC.FD.HT.MPO, PA=Paraventricular Nucleus,LAC.FD.HT.PV, SCH=Suprachiasmatic Nucleus,LAC.FD.HT.SCN, SON=Supraoptic Nucleus,LAC.FD.HT.SO, VMN=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, NTS=Solitary Nucleus,LPC.HL.SOL, PVN=Paraventricular Nucleus,LAC.FD.HT.PV, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: ARC=Arcuate Nucleus of Hypothalamus,LAC.FD.HT.AR, DMH=Dorsomedial Hypothalamic Nucleus,LAC.FD.HT.DM, LHA=Lateral Hypothalamic Nucleus,LAC.FD.HT.LTN, MPO=Median Preoptic Nucleus,LAC.FD.HT.MPO, PVH=Paraventricular Nucleus,LAC.FD.HT.PV, SCN=Suprachiasmatic Nucleus,LAC.FD.HT.SCN, VLPO=Ventrolateral Preoptic Nucleus,LAC.FD.HT.VLPO, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
map: PAG=Periaqueductal Gray Matter,LMC.MM.PAG, VMH=Ventromedial Hypothalamic Nucleus,LAC.FD.HT.VM
References
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- http://ajpregu.physiology.org/content/302/2/R215
- http://www.nature.com/nrendo/journal/v6/n8/fig_tab/nrendo.2010.93_F1.html
- http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.122.2314rep=rep1type=pdf
- http://neuroscience.uth.tmc.edu/s4/chapter04.html
- http://www.dana.org/Publications/ReportDetails.aspx?id=44217
- http://www.jneurosci.org/content/20/4/1589/F9.expansion