BrainRegionNPE NC BRA PO

Broca's Area Pars Opercularis

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This page covers biological details of component Broca's Area Pars Opercularis. Region is part of aHuman target integrated biological model.

• Top-down path to region: Cerebral Cortex -> Anterior Lobe (NC.LOBE.ANT) -> Prefrontal Cortex (NC.AL.PFC) -> Lateral Prefrontal Cortex (NC.AL.LPFC) -> Ventrolateral Prefrontal Cortex (NC.AL.VLPFC) -> Broca's Area (NPE.NC.PFC.BRA) -> Broca's Area Pars Opercularis (NPE.NC.BRA.PO) (see Mind Maps)
• Type: cortex
• Quality: L0
• Brain area: Neocortical Brain - Unimodal Execution Area (NPE)
• Area circuit: Execution by Auditory Inputs (AES)
• Brodmann ID: 44
• Role: cortex.generic
• Function: Speech Engine
• Notes to function:
  • Orbital Inferior Frontal Gyrus

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
NCP	NCP.NC.TPC	Temporopolar Cortex	feedforward-glu	Language-Related Regions (TC -> BA45, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LLC	LLC.HT.PRF.RTMG	Pontine Reticulotegmental Nucleus	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
LRC	LRC.HT.PRF.RPO	Oral Pontine Reticular Nucleus	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
NPE	NPE.NC.PMC.AFEF	Anterior Frontal Eye Field	feedforward-glu	Cortical Auditory System (IFC44 -> PMC8, abstract)

Thirdparty Circuits

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• Cortical Auditory System - see Reference (CP.CORTICAL-AUDITORY-SYSTEM)

AC22=Wernicke's area A4,NSA.NC.STG.A4
Belt42=Auditory Association Area,NSA.NC.TTG.A2
Core41=Primary Auditory Cortex,NSA.NC.TTG.A1
IFC44=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IFC45=Broca's Area,NPE.NC.PFC.BRA (see Lateral Prefrontal Cortex)
IPL40=Supramarginal Gyrus,NC.IPL.SMG (see Inferior Parietal Lobule)
PMC6=Ventral Premotor Cortex,MCA.NC.VPMC (see Premotor Cortex)
PMC8=Anterior Frontal Eye Field,NPE.NC.PMC.AFEF
STS22=Wernicke's area A3,NSA.NC.STG.A3

• Motor neurons control - see Reference (CM.CR-MN)

CR=Cerebellum,LLC.HT.CR (see Cerebellar Complex)
CTX=Anterior Lobe,NC.LOBE.ANT
EAMN=Anterior/Ventral Horn,SC.VH
EGMN=Anterior/Ventral Horn,SC.VH
FAMN=Anterior/Ventral Horn,SC.VH
FG=Fastigual Nucleus,LRC.HT.CR.FG
IP=Interposed Nucleus,LLC.HT.CR.IP (see Cerebellar Complex)
LT=Dentate Nucleus,LLC.HT.CR.DN
MRF=Medullary Reticular Formation,HL.RF
PRF=Pontine Reticular Formation,HT.RF
RD=Red Nucleus,LLC.MM.RD
VB=Vestibular Nuclei,LPC.HT.VBN

References

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• http://www.nature.com/neuro/journal/v12/n6/fig_tab/nn.2331_F5.html
• http://openagrosrl.com/www/page/292/