BrainRegionLLC HT PRF RTMG

Pontine Reticulotegmental Nucleus

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This page covers biological details of component Pontine Reticulotegmental Nucleus. Region is part of aHuman target integrated biological model.

• Top-down path to region: Hindbrain Metencephalon -> Pontine Reticular Formation (HT.RF) -> Pontine Reticular Formation, Lateral Column (HT.RF.LAT) -> Pontine Reticulotegmental Nucleus (LLC.HT.PRF.RTMG) (see Mind Maps)
• Type: nucleus
• Brain area: Lower Brain - Locomotion Control Area
• Role: processor.automatic
• Function: Mediate saccadic eye movements
• Notes to function: Inactivation leads to deficit of expression, but not learning

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Components

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• no child items defined

Connectivity

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Inbound Region Connections:

Source Area	Source Region	Source Name	Type	Reference
FMM	FMM.FD.MB.LMB	Lateral Mammillary Nucleus	excitatory-glu	Mammillary Body (LMB -> RTG)
	FMM.FD.MB.MMB	Medial Mammillary Nucleus	excitatory-glu	Mammillary Body (MMB -> RTG)
LPC	LPC.HL.TGS.STR	Spinal Trigeminal Nucleus	excitatory-glu	Eye blink reflex and pupillary light reflex (SpinalTrigeminal -> RF, abstract)
LRC	LRC.MM.SC.DEEP	Deep Superior Colliculus	excitatory-glu	Geniculate and Extyrageniculate Paths (SC -> RF, abstract)
	LRC.MM.SC.INT	Intermediate Superior Colliculus	excitatory-glu	Geniculate and Extyrageniculate Paths (SC -> RF, abstract)
NDM	NDM.NC.AL.VACG	Ventral Anterior Cingulate Area	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
NMA	NMA.NC.MC	Motor Cortex	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
	NMA.NC.SMC.F3	Supplementary Motor Area	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)
NPE	NPE.NC.BRA.PO	Broca's Area Pars Opercularis	excitatory-glu	Motor neurons control (CTX -> PRF, abstract)

Outbound Region Connections:

Target Area	Target Region	Target Name	Type	Reference
LRC	LRC.HT.CR.FN	Cerebellar Flocconodular Lobe	inhibitory-gaba	(unknown reference)
	LRC.HT.CR.VM	Cerebellar Vermis	inhibitory-gaba	(unknown reference)

Thirdparty Circuits

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• Mammillary Body (unknown reference)

• Horizontal saccades and smooth pursuit movements - see Reference

References

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• http://www.sciencedirect.com/science/article/pii/S0006899301025987