BrainRegionFMM NC PH LEC

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Lateral Entorhinal Cortex

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This page covers biological details of component Lateral Entorhinal Cortex. Region is part of aHuman target integrated biological model.

  • Top-down path to region: Cerebral Cortex -> Parahippocampal Lobe (NC.LOBE.PH) -> Anterior Parahippocampal Gyrus (FMM.NC.PHA) -> Rhinal Cortex (NC.PHA.RH) -> Entorhinal Cortex (FMM.NC.PH.ET) -> Lateral Entorhinal Cortex (FMM.NC.PH.LEC) (see Mind Maps)
  • Type: cortex
  • Brain area: Forebrain - Memory Management Area
  • Brodmann ID: 28
  • Role: processor
  • Function: Memory consolidation, emotional aspects
  • Notes to function: non-spatial input to HC; process information about individual items and locations based on a local frame of reference, primarily using external sensory input; it provides the hippocampus with information about content of experience

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Components

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Connectivity

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FMM.NC.PH.LEC.dot.png

Inbound Region Connections:

Source Area Source Region Source Name Type Reference
FAM FAM.FD.TH.PT Paratenial Nucleus of Thalamus excitatory-glu Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)
FAM.FT.AM.BP Parvicellular Basal Amygdaloid Nucleus excitatory-glu Principal Connections of Hippocampus (AM -> EC, abstract)
FMM FMM.FT.HF.SUBD Distal Subiculum excitatory-glu Attractor Network in Hippocampus (SUB -> EC, abstract)
FMM.NC.PH.PER Perirhinal Cortex feedforward-glu Visual Path to Hippocampus (PRPH -> ER, abstract)
LMC LMC.MM.VTA Ventral Tegmental Area modulatory-da Combining Novelty, Motivational Salience, and Reward to Control Attention and Learning (VTA -> EC, abstract)
LPC LPC.FD.TH.PV Paraventricular Nucleus of Thalamus excitatory-glu Contributions of Diencephalon to Recognition Memory (MID -> EC, abstract)
NSA NSA.NC.IT.TE Inferotemporal Cortex feedforward-glu McNaughton Spatial Processing Network (ITCortex -> EnthCortex, abstract)
NSA.NC.PH.PIR Piriform Cortex feedforward-glu KIV model of cortico-hippocampal formation with subcortical projections for motor actions (PC -> EC, abstract)
NSA.NC.STG.A3 Wernicke's area A3 feedforward-glu (unknown reference)
NSA.NC.STG.A4 Wernicke's area A4 feedforward-glu (unknown reference)

Outbound Region Connections:

Target Area Target Region Target Name Type Reference
FAM FAM.FT.AM.AB Accessory Basal Amygdaloid Nucleus excitatory-glu Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)
FAM.FT.AM.LAVM Ventromedial Amygdaloid Nucleus excitatory-glu Simplified model of hippocampal formation anatomy (EC -> Amyg, abstract)
FEC FEC.FT.ACC.CORE Nucleus Accumbens Core excitatory-glu Nucleus Accumbens (EC -> NACC, abstract)
FMM FMM.FT.HC.CA1D Distal CA1 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (ET -> CA1, abstract)
FMM.FT.HC.CA2 Dorsolateral Cornu Ammonis of Hippocampus excitatory-glu Amygdala and its network (EC -> HC, abstract)
FMM.FT.HC.CA3P Proximal CA3 of Hippocampus excitatory-glu Neuronal projections in the hippocampus (ET -> CA3, abstract)
FMM.FT.HC.DG Dentate Gyrus excitatory-glu Neuronal projections in the hippocampus (ET -> DG, abstract)
FMM.FT.HF.SUBP Proximal Subiculum excitatory-glu Visual Path to Hippocampus (ER -> H, abstract)
NDM NDM.FD.TH.MDM Medial Mediodorsal Nucleus of Thalamus excitatory-glu Contributions of Diencephalon to Recognition Memory (EC -> MDmc, abstract)

Thirdparty Circuits

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References

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